In vitro activity of thienyl-2-nitropropene compounds against Trypanosoma cruzi

Autor: Cristina Herrera, Gabriel A Vallejos, Randall Loaiza, Rodrigo Zeledón, Andrea Urbina, Silvia Sepúlveda-Boza

Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 104, Iss 7, Pp 980-985 (2009)

The in vitro activity of four 2-nitropropene derivatives, 1-(3-benzothienyl)-2-nitropropene (N1), 1-(3-thienyl)-2-nitropropene (N2), 1-(5-bromo-2-thienyl)-2-nitropropene (N3) and 1-(4-bromo-2-thienyl)-2-nitropropene (N4), were tested against cultures

Externí odkaz: https://doaj.org/article/dc276b6cd39c4adda167c23541891714

Increased Fibroblast Metabolic Activity of Collagen Scaffolds via the Addition of Propolis Nanoparticles

Autor: Jeimmy González-Masís, Jorge M. Cubero-Sesin, Yendry R. Corrales-Ureña, Sara González-Camacho, Nohelia Mora-Ugalde, Mónica Baizán-Rojas, Randall Loaiza, José Roberto Vega-Baudrit, Rodolfo J. Gonzalez-Paz

Publikováno v: Materials
Volume 13
Issue 14
Materials Vol 13 No. 14 1-13 2020
Repositorio UNA
Universidad Nacional de Costa Rica
instacron:UNA
Materials, Vol 13, Iss 3118, p 3118 (2020)

Propolis natural extracts have been used since ancient times due to their antioxidant, anti-inflammatory, antiviral, and antimicrobial activities. In this study, we produced scaffolds of type I collagen, extracted from Wistar Hanover rat tail tendons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::199564e16de811dbac4277dda1d20ff5

Role of extracellular histones in the cardiomyopathy of sepsis

Autor: Markus Bosmann, Peter A. Ward, Randall Loaiza, Florian Gebhard, Mark W. Russell, Lawrence Jajou, José Jalife, J. Vidya Sarma, Todd J. Herron, Héctor H. Valdivia, Miriam Kalbitz, Firas S. Zetoune, Markus Huber-Lang, Fatemeh Fattahi, Jamison J. Grailer, Katherine Campbell

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29(5)

The purpose of this study was to define the relationship in polymicrobial sepsis (in adult male C57BL/6 mice) between heart dysfunction and the appearance in plasma of extracellular histones. Procedures included induction of sepsis by cecal ligation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ae683cab873630a9554df2a474f415
https://pubmed.ncbi.nlm.nih.gov/25681459

Heterogeneity of ryanodine receptor dysfunction in a mouse model of catecholaminergic polymorphic ventricular tachycardia

Autor: José Jalife, Michael J. Ackerman, Nancy A. Benkusky, Héctor H. Valdivia, Sami F. Noujaim, Timothy A. Hacker, Randall Loaiza, Patricia P. Powers

Publikováno v: Circulation research. 112(2)

Rationale: Most cardiac ryanodine receptor (RyR2) mutations associated with catecholaminergic polymorphic ventricular tachycardia (CPVT) are postulated to cause a distinctive form of Ca 2+ release dysfunction. Considering the spread distribution of C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29886246672708389a84aace57ddce51
https://pubmed.ncbi.nlm.nih.gov/23152493

Partial and Controlled Depletion of Sarcoplasmic Reticulum (SR) Calcium Prevents Spontaneous Calcium Release and Tachyarrhythmias in a Mouse Model of CPVT

Autor: Liang Xiao, Georgina B. Gurrola, Carmen R. Valdivia, Héctor H. Valdivia, Randall Loaiza, Jifeng Zhang

Publikováno v: Heart Rhythm. 10:1741-1742

Background SR Ca 2+ ([Ca 2+ ]SR) overload during β-adrenergic stimulation precipitates spontaneous Ca 2+ release (SCR) and tachyarrhythmias in cardiomyocytes harboring catecholaminergic polymorphic ventricular tachycardia (CPVT)-linked RyR2 mutation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::943720888942f6d155bb3f36cba3d9ff
https://doi.org/10.1016/j.hrthm.2013.09.014