Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Randall L. Kincaid"'
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2189 (2008)
Synonymous codon replacement can change protein structure and function, indicating that protein structure depends on DNA sequence. During heterologous protein expression, low expression or formation of insoluble aggregates may be attributable to diff
Externí odkaz:
https://doaj.org/article/63bc402c9cde4d6499cee17d30938bfc
Autor:
Randall L. Kincaid
Publikováno v:
Phage Therapy: A Practical Approach ISBN: 9783030267353
The treatment of bacterial infections using bacteriophage has been utilized for nearly a century in the Republic of Georgia, the former Soviet Union and more recently in Poland. However, its use as a medical intervention in the United States has not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ccd6510734d4c98b490ce8fd0fce543
https://doi.org/10.1007/978-3-030-26736-0_7
https://doi.org/10.1007/978-3-030-26736-0_7
The power of basic research lies not only in its contribution to knowledge, but also in its potential for translation, adapting and developing work done in the laboratory to create innovative, novel approaches to prevent and control public health thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea614ec7c5748725bc66735f19dc149d
https://doi.org/10.1016/b978-0-12-805360-7.00015-0
https://doi.org/10.1016/b978-0-12-805360-7.00015-0
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 11, p e0004107 (2015)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf6e3e767c2d351c077db36e2ab36a66
http://europepmc.org/articles/PMC4652900?pdf=render
http://europepmc.org/articles/PMC4652900?pdf=render
Publikováno v:
Journal of Biological Chemistry. 275:35442-35447
Syk is an important protein-tyrosine kinase in immunoreceptor signaling. FceRI aggregation in mast cells induces tyrosine phosphorylation and increased enzymatic activity of Syk. The two adjacent tyrosines in the Syk activation loop are thought to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba73894701ceb90bfe636698520ff903
https://doi.org/10.1074/jbc.m004549200
https://doi.org/10.1074/jbc.m004549200
Publikováno v:
Biochemical Journal. 323:577-591
This review attempts to summarize what is known about tau phosphorylation in the context of both normal cellular function and dysfunction. However, conceptions of tau function continue to evolve, and it is likely that the regulation of tau distributi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56158ce9dc9e5a9a826aaf13373b1c68
https://doi.org/10.1042/bj3230577
https://doi.org/10.1042/bj3230577
Autor:
Randall L. Kincaid
Publikováno v:
Journal of Allergy and Clinical Immunology. 96:1170-1177
In this article I offer my own perspective on regulation of the immune system, which emphasizes some of the intracellular signaling events that underlie these biologic responses. Although this article highlights work that my collaborators and I have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71bd0bd58d9f0d2a568336bcc0dbad5
https://doi.org/10.1016/s0091-6749(95)70202-4
https://doi.org/10.1016/s0091-6749(95)70202-4
Autor:
Melvin L. Billingsley, John Q. Trojanowski, Marie L. Schmidt, C. Ellis, J. Martin, Virginia M.-Y. Lee, Randall L. Kincaid
Publikováno v:
Experimental Neurology. 126:178-184
Aberrant phosphorylation of tau is linked to formation of the paired helical filaments (PHF) seen in Alzheimer's disease. Protein kinases such as mitogen-activated protein kinase, and calcium-regulated protein kinases may, in part, be responsible for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56dc99bcfc207e355d695ea90552204a
https://doi.org/10.1006/exnr.1994.1056
https://doi.org/10.1006/exnr.1994.1056
Publikováno v:
International Immunology. 6:179-188
We have studied the TCR mediated signal transduction pathways involved in transcriptional regulation of the mouse IL-4 gene. The sequences extending from base pair -766 to +63 of the IL-4 gene were inserted upstream of a luciferase indicator gene. Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df58d0dd87886f76c16a4c4b3294bd35
https://doi.org/10.1093/intimm/6.2.179
https://doi.org/10.1093/intimm/6.2.179
Autor:
K. Ueki, Randall L. Kincaid
Publikováno v:
Journal of Biological Chemistry. 268:6554-6559
Two mammalian genes for the Ca(2+)-binding regulatory subunit of the calmodulin-dependent protein phosphatase (calcineurin) were identified recently, suggesting unique associations with tissue-specific catalytic subunits. The murine brain (beta 1) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::952ac64a60e2e1c63266ad10382bd789
https://doi.org/10.1016/s0021-9258(18)53286-5
https://doi.org/10.1016/s0021-9258(18)53286-5