Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Randall J. Mack"'
Autor:
Neil Singla, MD, Matthew Bindewald, MD, Sonia Singla, DO, David Leiman, MD, Harold Minkowitz, MD, Stewart W. McCallum, MD, Randall J. Mack, BS, Rosemary Keller, PhD, CRNP, Alex Freyer, PharmD, Wei Du, PhD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 6, Iss 6, p e1846 (2018)
Background:. A nanocrystal intravenous (IV) formulation of meloxicam is being studied with the aim of providing postoperative analgesia. Methods:. This randomized, multicenter, double-blind, placebo-controlled trial evaluated meloxicam IV 30 mg or pl
Externí odkaz:
https://doaj.org/article/5df992a1935b46138678c83cfeb09ac4
Autor:
Jonathan S. Jahr, Alex Freyer, Stewart W. McCallum, Randall J Mack, Sue Hobson, Wei Du, Shawn Searle, Kim Minger
Publikováno v:
Clinical pharmacology in drug development, vol 9, iss 7
Clinical Pharmacology in Drug Development
Clinical Pharmacology in Drug Development
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are effective treatments for pain but may induce bleeding events due to platelet dysfunction associated with inhibition of cyclooxygenase (COX)‐1 impairing thromboxane production. An intravenous nanoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b18cb4268f0371db46b44bdf75898b5
https://doi.org/10.1002/cpdd.772
https://doi.org/10.1002/cpdd.772
Autor:
Stewart W. McCallum, Kipling P Sharpe, Randall J Mack, Richard D Berkowitz, William A Tyndall, David Boyer, Wei Du
Publikováno v:
Journal of Pain Research. 13:221-229
Objective A Phase 3 randomized multicenter, double-blind, placebo-controlled trial (NCT02720692) compared once-daily intravenous (IV) meloxicam 30 mg to placebo, when added to the standard of care pain management regimens, in adults with moderate-to-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae35b102875c4631a076d27cc371c529
https://doi.org/10.2147/jpr.s216219
https://doi.org/10.2147/jpr.s216219
Autor:
Neil Singla, Randall J Mack, Stewart W. McCallum, Tong J. Gan, Sue Hobson, Eugene R. Viscusi, Wei Du, Sergio D. Bergese
Publikováno v:
Regional Anesthesia & Pain Medicine. 44:360-368
Background and objectivesTo describe the safety and tolerability of intravenous meloxicam compared with placebo across all phase II/III clinical trials.MethodsSafety data and opioid use from subjects with moderate to severe postoperative pain who rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a56d365dda203ead32ac0f9a206b9ea
https://doi.org/10.1136/rapm-2018-100184
https://doi.org/10.1136/rapm-2018-100184
Autor:
Richard D Berkowitz, Richard Steinfeld, Erin Coyle, Wei Du, Alex Freyer, Alexander P. Sah, Libby Black, Randall J Mack, Stewart W. McCallum
Publikováno v:
Pain Medicine: The Official Journal of the American Academy of Pain Medicine
ObjectiveTo evaluate the effect of perioperative meloxicam IV 30 mg on opioid consumption in primary total knee arthroplasty (TKA).DesignMulticenter, randomized, double-blind, placebo-controlled trial.SubjectsIn total, 181 adults undergoing elective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43de5b3543ab4b723156f1f96771e752
https://pubmed.ncbi.nlm.nih.gov/33502533
https://pubmed.ncbi.nlm.nih.gov/33502533
Publikováno v:
Pain management. 11(3)
Meloxicam for intravenous use (meloxicam iv.) is a nanocrystal formulation with improved dissolution properties and shortened time to peak plasma concentrations versus oral meloxicam. In Phase III and IIIb trials, 30 mg once daily relieved pain follo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99cbd76b674fe9ea05ad3300d11928c4
https://pubmed.ncbi.nlm.nih.gov/33291975
https://pubmed.ncbi.nlm.nih.gov/33291975
Autor:
Libby Black, Wei Du, Stewart W. McCallum, Alex Freyer, Jorge E. Marcet, Swapna U. Karkare, Randall J Mack, Vamshi Ruthwik Anupindi, Drishti Shah, Jennifer D. Silinsky
Publikováno v:
Pain management. 11(1)
Aim: Evaluate safety/efficacy of intravenous meloxicam in a colorectal enhanced recovery after surgery protocol. Methods: Adults undergoing primary open or laparoscopic colorectal surgery with bowel resection and/or anastomosis received meloxicam IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850419e51232572ab98f702718ae2375
https://pubmed.ncbi.nlm.nih.gov/33094682
https://pubmed.ncbi.nlm.nih.gov/33094682
Autor:
Campbell P Howard, Alex Freyer, Randall J Mack, Wei Du, Stewart W. McCallum, Deborah R Tunick, Ira J. Gottlieb
Publikováno v:
Journal of Pain Research
Objective This randomized, double-blind, placebo-controlled study evaluated the safety and efficacy of an intravenous (IV) nanocrystal formulation of meloxicam in subjects with moderate-to-severe pain following a standardized unilateral bunionectomy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a1422764b21230d02bae9462adf708
http://europepmc.org/articles/PMC5819580
http://europepmc.org/articles/PMC5819580
Publikováno v:
Anesthesia and Analgesia
BACKGROUND: An intravenous (IV) formulation of meloxicam was developed for moderate-to-severe pain management. This study evaluated the safety and efficacy of meloxicam IV after open abdominal hysterectomy. Meloxicam IV is an investigational product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df640a00fc44c8839fe728d5915e0a36
https://pubmed.ncbi.nlm.nih.gov/31094806
https://pubmed.ncbi.nlm.nih.gov/31094806
Autor:
Stewart W. McCallum, Randall J Mack, Swapna U. Karkare, Vamshi Ruthwik Anupindi, Teresa Galas, Libby Black, Wei Du, Conor P. Delaney, Jennifer D. Silinsky, Alex Freyer, Drishti Shah
Publikováno v:
Gastroenterology. 158:S-1512
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a9a32452fd34e845ffd9c99fe068286
https://doi.org/10.1016/s0016-5085(20)34449-8
https://doi.org/10.1016/s0016-5085(20)34449-8