Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Randall G. Stehle"'
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 38:532-536
A sensitive liquid chromatographic method with electrochemistry (LC/EC) was developed for the determination of trace of minoxidil in hamster skin follicles after topical administration of the ear using various formulations. The minoxidil in the sebac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f9e7de740845ab77253334d5697aab
https://doi.org/10.1016/j.jpba.2005.01.032
https://doi.org/10.1016/j.jpba.2005.01.032
Autor:
Richard A. Nugent, Donn G. Wishka, Lester A. Dolak, Azhwarsamy Jeganathan, Eric P. Seest, Laurice A. Kopta, Randall G. Stehle, Joel Morris, Wendy L. White, Stephen T. Schlachter, Janice M. Friis, Susan M. Poppe, Wade J. Adams, Murphy Michael J, David R. Graber, Robert A. Olmsted, Fusen Han, John D. Hosley, Cleek Gary J, Richard L. Voorman, Poel Toni-Jo, and W. Gary Tarpley, William Watt, Keiser Bj, Y. Yagi, Kevin Stefanski, Richard C. Thomas, Steven M. Swaney, Thomas M. Castle
Publikováno v:
Journal of Medicinal Chemistry. 41:1357-1360
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2821bb7f749a376a1a2d6c7a50b95408
https://doi.org/10.1021/jm9801049
https://doi.org/10.1021/jm9801049
Autor:
Carolyn Biles, Keiser Bj, David B. Evans, Joel Morris, Richard L. Voorman, Raymond A. Morge, Satish K. Sharma, Laurice A. Kopta, John D. Hosley, Janice M. Friis, W G Tarpley, Wade J. Adams, Kevin Stefanski, Donna L. Romero, Randall G. Stehle, Donn G. Wishka, Richard C. Thomas, Y. Yagi, T. J. Poel, Robert A. Olmsted
Publikováno v:
Journal of Medicinal Chemistry. 39:3769-3789
A novel class of bis(heteroaryl)piperazine (BHAP) analogs which possesses the ability to inhibit NNRTI (non-nucleoside reverse transcriptase inhibitor) resistant recombinant HIV-1 reverse transcriptase (RT) and NNRTI resistant variants of HIV-1 has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01ee3a1aeac60f7c3685b5ac0d3ab3a
https://doi.org/10.1021/jm960158n
https://doi.org/10.1021/jm960158n
Autor:
Kevin Haley, Randall G. Stehle, Guang Wei Lu, Susan Ciotti, Roy Haskell, Daniel Du, Conglin Fan, Jessica Cervantes, Michael M. Morgen, Franz Lembke, Dan Smithey
Publikováno v:
International Journal of Pharmaceutics.
This study explored the utility of topically applied polymeric nanoparticle suspensions to target delivery of poorly water-soluble drugs to hair follicles. Several formulations of amorphous drug/polymer nanoparticles were prepared from ethyl cellulos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6883c3ad3ace288f16b005b10bd8fbab
https://doi.org/10.1016/j.ijpharm.2011.06.019
https://doi.org/10.1016/j.ijpharm.2011.06.019
Autor:
Kevin J Stefanski, Allen E. Buhl, Heinrich J. Schostarez, Bharat V. Kamdar, Marshall N. Brunden, Lisa Marie Thomasco, Garland A. Johnson, Kathy L. Shull, Daniel J. Waldon, Randall G. Stehle, A. R. Diani, Michael J. Mulholland, Theresa M. Schwartz, Steven J. Conrad, Robert C. Gadwood, Marc F. Kubicek
Publikováno v:
Journal of Investigative Dermatology. 98:315-319
The opening of intracellular potassium channels has been suggested as a mechanism regulating hair growth. Enhancing the flux of potassium ions is a mechanism shared by several structurally diverse antihypertensive agents including minoxidil sulfate (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c37d9c08572de8fad1039b8845b74a
https://doi.org/10.1111/1523-1747.ep12499788
https://doi.org/10.1111/1523-1747.ep12499788
Autor:
T.O. Oesterling, Randall G. Stehle
Publikováno v:
Journal of Pharmaceutical Sciences. 66:1590-1595
The stability of prostaglandin El and dinoprostone was investigated at the extremes of the pH range (≤ 3 and ≥ 10) in the sequence prostaglandin E → prostaglandin A → prostaglandin B. The degradation rate is first order with hydrogen-ion and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7770c29ea9c0a8e5167e949cacc9694
https://doi.org/10.1002/jps.2600661123
https://doi.org/10.1002/jps.2600661123
Autor:
Randall G. Stehle
Publisher Summary This chapter discusses the physical chemistry, stability, and handling of prostaglandins E 2 , F 2α , D 2 , and I 2 . The molecular configuration of crystalline PGE 2 has been assessed by X-ray diffraction and appears to have the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e41e4a03ff30a865e0077236aace0d7
https://doi.org/10.1016/0076-6879(82)86216-2
https://doi.org/10.1016/0076-6879(82)86216-2
Autor:
T.O. Oesterling, W.L. Miller, Walter Morozowich, Randall G. Stehle, S.L. Douglas, J.R. Weeks, C.F. Lawson
Publikováno v:
Journal of pharmaceutical sciences. 68(7)
Dinoprostone para-substituted phenyl esters were synthesized in attempt to improve the solid-state stability of the parent prostaglandin. A phenol series covering a wide melting-point range was employed, and a linear relationship was observed between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de8d60a1ff3fbc28b2f84f9abfb3bbe
https://pubmed.ncbi.nlm.nih.gov/458598
https://pubmed.ncbi.nlm.nih.gov/458598
Autor:
Randall G. Stehle, William I. Higuchi
Publikováno v:
Journal of pharmaceutical sciences. 61(12)
A diffusional model describing steady-state transport of neutral compounds and ionizing weak acids and bases in the three-phase (water-oil-water) system is presented. The present study applies this model, consisting of three barriers in series, to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5917092ee43ad207556db565d35ee59
https://pubmed.ncbi.nlm.nih.gov/4638098
https://pubmed.ncbi.nlm.nih.gov/4638098
Autor:
Randall G. Stehle, William I. Higuchi
Publikováno v:
Journal of Pharmaceutical Sciences. 56:1367-1368
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd597bd296efbe4b345139d7e0c3685
https://doi.org/10.1002/jps.2600561040
https://doi.org/10.1002/jps.2600561040