Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Randall D. York"'
Publikováno v:
Molecular and Cellular Biology. 23:5005-5017
The origin recognition complex (ORC) plays a central role in eukaryotic DNA replication. Here we describe a unique ORC-like complex in Tetrahymena thermophila, TIF4, which bound in an ATP-dependent manner to sequences required for cell cycle-controll
Autor:
Philip J.S. Stork, Randall D. York, Edwin W. McCleskey, Savraj S. Grewal, Paula E. Stenberg, Derek C. Molliver
Publikováno v:
Molecular and Cellular Biology. 20:8069-8083
Neurotrophins promote multiple actions on neuronal cells including cell survival and differentiation. The best-studied neurotrophin, nerve growth factor (NGF), is a major survival factor in sympathetic and sensory neurons and promotes differentiation
Publikováno v:
Current Opinion in Neurobiology. 9:544-553
Extracellular-signal-regulated kinases (ERKs) are emerging as important regulators of neuronal function. Recent advances have increased our understanding of ERK signalling at the molecular level. In particular, it has become evident that multiple sec
Publikováno v:
Journal of Biological Chemistry. 273:8240-8247
Induction of neuronal differentiation of the rat pheochromocytoma cell line, PC12 cells, by nerve growth factor (NGF) requires activation of the mitogen-activated protein (MAP) kinase or extracellular signal-regulated kinase (ERK). cAMP-dependent pro
Publikováno v:
Cell. 89(1):73-82
Cyclic adenosine monophosphate (cAMP) has tissue-specific effects on growth, differentiation, and gene expression. We show here that cAMP can activate the transcription factor Elk-1 and induce neuronal differentiation of PC12 cells via its activation
Publikováno v:
Contemporary Neuroscience ISBN: 9781588295293
The concept of cell cycle-related neuronal death (CRND) has now been in the literature for more than a decade. The first evidence linking the loss of cell cycle control with neuronal death arose from studies in transgenic mice in which cell cycle pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3928d24d746d26b56ceb97086d7bb225
https://doi.org/10.1007/978-1-59745-021-8_21
https://doi.org/10.1007/978-1-59745-021-8_21
Publikováno v:
Experimental hematology. 28(3)
Objective To identify tyrosine phosphorylated proteins that interact with CrkL in Bcr-Abl–expressing cells and analyze the function of that association. Materials and Methods Immunoprecipitation of CrkL was performed on lysates from parental cells
Autor:
Randall D. York, Philip J.S. Stork, Savraj S. Grewal, Gary Banker, Angela Horgan, Ginger S. Withers
Publikováno v:
The Journal of biological chemistry. 275(5)
Activity-dependent regulation of neuronal events such as cell survival and synaptic plasticity is controlled by increases in neuronal calcium levels. These actions often involve stimulation of intracellular kinase signaling pathways. For example, the
Autor:
Hong Yao, Randall D. York, Cindy L. Ellig, Tara J. Dillon, Philip J.S. Stork, Edwin W. McCleskey, Stephani P. Eckert
Publikováno v:
Nature. 392(6676)
Activation of mitogen-activated protein (MAP) kinase (also known as extracellular-signal-regulated kinase, or ERK)1 by growth factors can trigger either cell growth or differentiation. The intracellular signals that couple growth factors to MAP kinas
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 25:S309-S309