Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Randall D. Wolcott"'
Autor:
Craig D Tipton, Randall D Wolcott, Nicholas E Sanford, Clint Miller, Gita Pathak, Talisa K Silzer, Jie Sun, Derek Fleming, Kendra P Rumbaugh, Todd D Little, Nicole Phillips, Caleb D Phillips
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008511 (2020)
The clinical importance of microbiomes to the chronicity of wounds is widely appreciated, yet little is understood about patient-specific processes shaping wound microbiome composition. Here, a two-cohort microbiome-genome wide association study is p
Externí odkaz:
https://doaj.org/article/4bc8fb4acb0341d69769beed7f7b5973
Autor:
Sarah J Morgan, Soyeon I Lippman, Gilbert E Bautista, Joe J Harrison, Christopher L Harding, Larry A Gallagher, Ann-Chee Cheng, Richard Siehnel, Sumedha Ravishankar, Marcia L Usui, John E Olerud, Philip Fleckman, Randall D Wolcott, Colin Manoil, Pradeep K Singh
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007511 (2019)
While much is known about acute infection pathogenesis, the understanding of chronic infections has lagged. Here we sought to identify the genes and functions that mediate fitness of the pathogen Pseudomonas aeruginosa in chronic wound infections, an
Externí odkaz:
https://doaj.org/article/04a0e9429ad1465aa981669a15696103
Autor:
Craig D Tipton, Nicholas E Sanford, Jake A Everett, Rebecca A Gabrilska, Randall D Wolcott, Kendra P Rumbaugh, Caleb D Phillips
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221565 (2019)
Chronic wound infections are increasingly recognized to be dynamic and polymicrobial in nature, necessitating the development of wound models which reflect the complexities of infection in a non-healing wound. Wound slough isolated from human chronic
Externí odkaz:
https://doaj.org/article/65e6a7dcd03e4e6fb646d74b08a9fdfe
Autor:
Randall D. Wolcott
Publikováno v:
Clinical Microbiology Newsletter. 42:181-186
This review describes what is currently known regarding the interplay of microbial biofilms and the chronic illness known as Alzheimer's disease. Additionally, a view into the future of clinical microbiology as it responds to assessment of biofilms i
Biofilm exacerbates antibiotic resistance: Is this a current oversight in antimicrobial stewardship?
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 9, Iss 1, Pp 1-5 (2020)
Antimicrobial Resistance and Infection Control
Antimicrobial Resistance and Infection Control
Objective To raise awareness of the role of environmental biofilm in the emergence and spread of antibiotic resistance and its consideration in antimicrobial stewardship. Background Antibiotic resistance is a major threat to public health. Overuse of
Autor:
Randall G Cook, Gregory S. Schultz, Randall D. Wolcott, Kevin Y. Woo, Eric Johnson, Curtis E. Jones, Michel H.E. Hermans, Richard Simman, John P. Kennedy, Dot Weir
Publikováno v:
Journal of wound care. 29(Sup7)
Biofilms play a central role in the chronicity of non-healing lesions such as venous leg ulcers and diabetic foot ulcers. Therefore, biofilm management and treatment is now considered an essential part of wound care. Many antimicrobial treatments, wh
Autor:
Trevor Dalton, Scot E Dowd, Randall D Wolcott, Yan Sun, Chase Watters, John A Griswold, Kendra P Rumbaugh
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27317 (2011)
Chronic wound infections are typically polymicrobial; however, most in vivo studies have focused on monospecies infections. This project was designed to develop an in vivo, polymicrobial, biofilm-related, infected wound model in order to study multis
Externí odkaz:
https://doaj.org/article/8c443670ca774ca48632a80ed85f0d8a
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3326 (2008)
BACKGROUND: Diabetic extremity ulcers are associated with chronic infections. Such ulcer infections are too often followed by amputation because there is little or no understanding of the ecology of such infections or how to control or eliminate this
Externí odkaz:
https://doaj.org/article/319aa3a78a9d429c94ee86effc1f8e15
Autor:
David Leaper, Masahiro Tachi, Gregory S. Schultz, Thomas Bjarnsholt, Randall D. Wolcott, Garth A. James, Paul Stoodley, Andrew J. McBain, Theresa Swanson, Matthew Malone
Publikováno v:
Wound Repair and Regeneration. 25:744-757
Background: Despite a growing consensus that biofilms contribute to a delay in the healing of chronic wounds, conflicting evidence pertaining to their identification and management can lead to uncertainty regarding treatment. This, in part, has been
Autor:
Randall D. Wolcott, Caleb D. Phillips, Tigga Kingston, Richard A. Wolcott, Craig D. Tipton, Marilyn E. Mathew
Publikováno v:
Wound Repair and Regeneration. 25:673-679
Polymicrobial bacterial infection is an important factor contributing to wound chronicity. Consequently, clinicians frequently adopt a biofilm-based wound care approach, in which wounds are treated utilizing DNA sequencing information about microbial