Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Randall D. Reif"'
Publikováno v:
Journal of Chemical Education. 93:2084-2088
Integrative, research-based experiences have shown tremendous potential as effective pedagogical approaches. Pharmaceutical development is an exciting field that draws heavily on organic chemistry and biochemistry techniques. A capstone drug synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60b1ab645b2cf95f67d43f389df6cc77
https://doi.org/10.1021/acs.jchemed.6b00048
https://doi.org/10.1021/acs.jchemed.6b00048
Publikováno v:
Analytical and Bioanalytical Chemistry. 397:3387-3396
The temporal dynamics of Fas-induced apoptosis is elucidated. Jurkat cells are captured on the affinity surface of a microdevice coated with anti-CD95, an antibody known to induce apoptosis in cells via the extrinsic (caspase 8) pathway. The timing o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb66af1589563c3686b21da82fb0a638
https://doi.org/10.1007/s00216-010-3567-1
https://doi.org/10.1007/s00216-010-3567-1
Publikováno v:
Analytical and Bioanalytical Chemistry. 396:1177-1185
Early detection of apoptotic cells via caspase activity is demonstrated with fast response time. Fluorescence correlation spectroscopy (FCS) is used to identify the presence of a cleaved fluorogenic probe based on the fluorescence of rhodamine 110 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63114675393e23b5bfff977584af99b
https://doi.org/10.1007/s00216-009-3298-3
https://doi.org/10.1007/s00216-009-3298-3
Publikováno v:
Analytica Chimica Acta. 651:85-90
The ability to quickly measure flow parameters in microfluidic devices is critical for micro total analysis system (μTAS) applications. Macrofluidic methods to assess flow suffer from limitations that have made conventional methods unsuitable for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47be459472ef20a120c98010e7bb9920
https://doi.org/10.1016/j.aca.2009.08.007
https://doi.org/10.1016/j.aca.2009.08.007
Publikováno v:
Analytical and Bioanalytical Chemistry. 395:787-795
A microfluidic device is designed and demonstrated for the simultaneous capture and induction of apoptosis in Jurkat cells. In this unique case, the cell capture event initiates a biological process. The device features a single channel made from pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2444240fcffd975c050a2edf65b83b8c
https://doi.org/10.1007/s00216-009-3024-1
https://doi.org/10.1007/s00216-009-3024-1
Publikováno v:
TrAC Trends in Analytical Chemistry. 26:884-894
In recent years, single-molecule detection has evolved from focusing on detecting a single molecule to examining molecular interactions in various systems. This review discusses the recent progress of single-molecule-fluorescence detection with respe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50b6ce8fef664ce6f0793dba7b4b4c70
https://doi.org/10.1016/j.trac.2007.09.003
https://doi.org/10.1016/j.trac.2007.09.003
Publikováno v:
Analytical and Bioanalytical Chemistry. 395:2411-2413
Differential mobility cytometry (DMC) has recently been established as a powerful method to capture cells and study adhesion processes. DMC uses an oscillation system and cell affinity chromatography to monitor cells as they adhere to a surface. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8591ece3dfed16ff008887234a427db3
https://doi.org/10.1007/s00216-009-3154-5
https://doi.org/10.1007/s00216-009-3154-5
Publikováno v:
Analytica chimica acta. 598(1)
A method for investigation of photobleaching and saturation of single molecules by fluorophore recrossing events in a laser beam is described. The diffraction-limited probe volumes encountered in single-molecule detection (SMD) produce high excitatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403a37c48f4894e01bfce571484a57a5
https://pubmed.ncbi.nlm.nih.gov/17693317
https://pubmed.ncbi.nlm.nih.gov/17693317
Publikováno v:
Analytical Methods. 2:996
Apoptosis, or programmed cell death, has been shown to play a role in a number of diseases, including heart disease and cancer. Apoptosis is also a vital cellular process that helps to regulate tissue growth, fetal development, immune response, and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e0912b64a25a43984b34c4a7303a867
https://doi.org/10.1039/c0ay00247j
https://doi.org/10.1039/c0ay00247j