Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Randall CP"'
Autor:
Nass, NM, Farooque, S, Hind, C, Wand, ME, Randall, CP, Sutton, JM, Seipke, RF, Rayner, C, O'Neill, AJ
Of the thousands of natural product antibiotics discovered to date, only a handful have been developed for the treatment of bacterial infection. The clinically unexploited majority likely include compounds with untapped potential as antibacterial dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::aaa13654eefef2e3ad1065055c215d49
Autor:
Gupta, A, Monteferrante, C, Rasina, D, Leitis, G, Randall, CP, Tomlinson, JH, Jirgensons, A, Goessens, WHF, Hays, JP, O'Neill, AJ
GSK2251052 is a broad-spectrum antibacterial inhibitor of leucyl tRNA-synthetase (LeuRS) that has been evaluated in Phase II clinical trials. Here we report the identification of a clinical isolate of Staphylococcus aureus that exhibits reduced susce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::81faca4bc1891e0c427f9dc1c33da3c1
Autor:
Galarion LH; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK., Mitchell JK; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK., Randall CP; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK., O'Neill AJ; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
Publikováno v:
The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2023 Mar 02; Vol. 78 (3), pp. 646-655.
Autor:
Galarion LH; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK., Mohamad M; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK., Alzeyadi Z; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK., Randall CP; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK., O'Neill AJ; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
Publikováno v:
The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2021 May 12; Vol. 76 (6), pp. 1467-1471.
Autor:
Kime L; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Randall CP; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Banda FI; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Coll F; Infection Biology Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom., Wright J; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Richardson J; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Empel J; Department of Epidemiology and Clinical Microbiology, National Medicines Institute, Warsaw, Poland., Parkhill J; Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom., O'Neill AJ; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom a.j.oneill@leeds.ac.uk.
Publikováno v:
MBio [mBio] 2019 Oct 29; Vol. 10 (5). Date of Electronic Publication: 2019 Oct 29.
Autor:
Randall CP; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Gupta A; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Utley-Drew B; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Lee SY; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., Morrison-Williams G; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom., O'Neill AJ; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom a.j.oneill@leeds.ac.uk.
Publikováno v:
MSphere [mSphere] 2018 Dec 12; Vol. 3 (6). Date of Electronic Publication: 2018 Dec 12.
Autor:
Charlton MH; Oxford Drug Design Ltd., Oxford Centre for Innovation, New Road, Oxford, OX1 1BY. U.K., Aleksis R; Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV-1006, Latvia., Saint-Leger A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac, 10, 08028 Barcelona, Catalonia, Spain.; ICREA, Pg. Lluís Company 23, 08010 Barcelona, Catalonia, Spain., Gupta A; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, U.K., Loza E; Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV-1006, Latvia., Ribas de Pouplana L; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac, 10, 08028 Barcelona, Catalonia, Spain.; ICREA, Pg. Lluís Company 23, 08010 Barcelona, Catalonia, Spain., Kaula I; Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV-1006, Latvia., Gustina D; Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV-1006, Latvia., Madre M; Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV-1006, Latvia., Lola D; Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV-1006, Latvia., Jaudzems K; Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV-1006, Latvia., Edmund G; Oxford Drug Design Ltd., Oxford Centre for Innovation, New Road, Oxford, OX1 1BY. U.K., Randall CP; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, U.K., Kime L; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, U.K., O'Neill AJ; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, U.K., Goessens W; Erasmus University Medical Center Rotterdam, Department of Medical Microbiology and Infectious Diseases, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands., Jirgensons A; Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV-1006, Latvia., Finn PW; Oxford Drug Design Ltd., Oxford Centre for Innovation, New Road, Oxford, OX1 1BY. U.K.; Department of Applied Computing, University of Buckingham, Hunter Street, Buckingham, MK18 1EG, U.K.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2018 Jan 18; Vol. 9 (2), pp. 84-88. Date of Electronic Publication: 2018 Jan 18 (Print Publication: 2018).
Autor:
Nass NM; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Farooque S; School of Chemistry, University of Leeds, Leeds, LS2 9JT, UK., Hind C; Public Health England, National Infection Service, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Wand ME; Public Health England, National Infection Service, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Randall CP; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Sutton JM; Public Health England, National Infection Service, Porton Down, Salisbury, Wiltshire, SP4 0JG, UK., Seipke RF; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Rayner CM; School of Chemistry, University of Leeds, Leeds, LS2 9JT, UK., O'Neill AJ; Antimicrobial Research Centre and School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK. a.j.oneill@leeds.ac.uk.
Publikováno v:
Scientific reports [Sci Rep] 2017 Dec 12; Vol. 7 (1), pp. 17419. Date of Electronic Publication: 2017 Dec 12.
Autor:
Elkrewi E; Antimicrobial Research Centre and School of Molecular and Cellular Biology, University of Leeds, Leeds LS29JT, UK., Randall CP; Antimicrobial Research Centre and School of Molecular and Cellular Biology, University of Leeds, Leeds LS29JT, UK., Ooi N; Antimicrobial Research Centre and School of Molecular and Cellular Biology, University of Leeds, Leeds LS29JT, UK., Cottell JL; Department of Microbiology, Northampton General Hospital NHS Trust, Cliftonville, Northampton NN15BD, UK., O'Neill AJ; Antimicrobial Research Centre and School of Molecular and Cellular Biology, University of Leeds, Leeds LS29JT, UK.
Publikováno v:
The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2017 Nov 01; Vol. 72 (11), pp. 3043-3046.
Autor:
Renzoni A; Service of Infectious Diseases, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland., Von Dach E; Infection Control Program, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland., Landelle C; Hospital Hygiene Unit, Grenoble Alpes University Hospital, Grenoble, France., Diene SM; Genomic Research Laboratory, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland., Manzano C; Service of Infectious Diseases, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland., Gonzales R; Los Angeles Biomedical Research Institute at Harbor-UCLA, Torrance, California, USA., Abdelhady W; Los Angeles Biomedical Research Institute at Harbor-UCLA, Torrance, California, USA., Randall CP; Antimicrobial Research Centre, University of Leeds, Leeds, United Kingdom., Bonetti EJ; Genomic Research Laboratory, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland., Baud D; Genomic Research Laboratory, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland., O'Neill AJ; Antimicrobial Research Centre, University of Leeds, Leeds, United Kingdom., Bayer A; Los Angeles Biomedical Research Institute at Harbor-UCLA, Torrance, California, USA.; Geffen School of Medicine at UCLA, Los Angeles, California, USA., Cherkaoui A; Service of Infectious Diseases, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland., Schrenzel J; Genomic Research Laboratory, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland., Harbarth S; Service of Infectious Diseases, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland.; Infection Control Program, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland., François P; Genomic Research Laboratory, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland patrice.francois@genomic.ch.
Publikováno v:
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2017 Sep 22; Vol. 61 (10). Date of Electronic Publication: 2017 Sep 22 (Print Publication: 2017).