Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Randall C. Cutlip"'
Autor:
Randall C. Cutlip, Jürgen A. Richt, Eric M. Nicholson, Janice M. Miller, Robert A. Kunkle, Justin J. Greenlee, Marcus E. Kehrli, Amir N. Hamir
Publikováno v:
Journal of Veterinary Diagnostic Investigation. 23:407-420
Prion diseases or transmissible spongiform encephalopathies (TSEs) of animals include scrapie of sheep and goats; transmissible mink encephalopathy (TME); chronic wasting disease (CWD) of deer, elk and moose; and bovine spongiform encephalopathy (BSE
Autor:
Janice M. Miller, Randall C. Cutlip, Eric M. Nicholson, T. Baron, A. G. Biacabe, Brian W. Brunelle, Robert A. Kunkle, Jürgen A. Richt, Amir N. Hamir
Publikováno v:
Journal of Animal Science. 85:3142-3147
Two regulatory region polymorphisms in the prion gene of cattle have been reported to have an association with resistance to classical bovine spon- giform encephalopathy (BSE). However, it is not known if this association also applies to other transm
Autor:
Juergen A. Richt, Amir N. Hamir, Janice M. Miller, Robert A. Kunkle, Melanie J. Chaplin, Randall C. Cutlip, Allen L. Jenny, M.J. Stack
Publikováno v:
Journal of Veterinary Diagnostic Investigation. 16:316-321
This is a final report of an experimental transmission of sheep scrapie agent by intracerebral inoculation to Rocky Mountain elk ( Cervus elaphus nelsoni). It documents results obtained in experimental ( n = 6) and control ( n = 2) elk. During the fi
Publikováno v:
Veterinary Pathology. 41:78-81
Transmissible spongiform encephalopathies (TSEs) are fatal neurologic diseases. Infection by the causative agent, a prion, induces accumulations of an abnormal form of prion protein (PrPres) in tissues of nervous and lymphoid systems. Presence of cha
Autor:
Janice M. Miller, Katherine I. O'Rourke, Noelle E. Cockett, S. J. Ryder, Steven M. Parish, Allen L. Jenny, Randall C. Cutlip, Gerald A. H. Wells, Donald P. Knowles, Amir N. Hamir, Timothy V. Baszler, Thomas E. Besser
Publikováno v:
Journal of Clinical Microbiology. 38:3254-3259
Ovine scrapie is a member of the transmissible spongiform encephalopathies (TSEs), a heterogeneous family of fatal neurologic disorders characterized by deposition of an abnormal isoform (prion protein [PrP] PrP-Sc) of a cellular sialoglycoprotein in
Publikováno v:
Research in Veterinary Science. 87:329-331
The minimum intravenous infectious dose for ovine progressive pneumonia virus (OPPV) WLC1 was determined using twenty-four 6 month-old lambs. Twelve groups of two 6 month-old lambs were inoculated intravenously (i.v.) with tissue culture fluid contai
Publikováno v:
Journal of Comparative Pathology. 119:277-292
Summary Six sheep, aged 6–8 months and seronegative for pestivirus, were inoculatedintranasally, through the tracheal wall, and intrabronchially with a non-cytopathogenic isolate of bovine viral diarrhoe virus (ncpBVDV). Infected sheep were killed
Publikováno v:
Journal of Comparative Pathology. 118:163-167
Summary Ten lambs aged 8 weeks were inoculated intratracheally through the tracheal wall with lipopolysaccharide from Pasteurella haemolytica A1 and examined in chronological sequence by light and electron microscopy for pulmonary lesions. An acute f
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 697:223-229
Scrapie in sheep and in goats is the prototype of a group of transmissible spongiform encephalopathies (TSE). A feature of these diseases is the accumulation in the brain of rod shaped fibrils that form from an aggregated protein that is a protease-r
Publikováno v:
Journal of Microcolumn Separations. 7:521-527
Transmissible spongiform encephalopathies of animals and humans are infectious diseases that cause progressive degenerative disorders of the central nervous system. These diseases are caused by an accumulation in the lysosymes of a modified normal ce