Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Randall B. Lauffer"'
Autor:
Randall B. Lauffer
Publikováno v:
Iron and Human Disease ISBN: 9781351073899
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a9060ea05bec02dcfb793a19a24ac83
https://doi.org/10.1201/9781351073899-20
https://doi.org/10.1201/9781351073899-20
Autor:
Marga Spiller, Normand J. Cloutier, Randall B. Lauffer, Peter Caravan, Thomas J. Mcmurry, Jeffrey J. Ellison, Jaclyn M. Chasse, Claudio Luchinat, Giacomo Parigi, Sarah A. McDermid
Publikováno v:
Inorganic Chemistry. 46:6632-6639
The amphiphilic gadolinium complex MS-325 ((trisodium-{(2-(R)-[(4,4-diphenylcyclohexyl) phosphonooxymethyl] diethylenetriaminepentaacetato) (aquo)gadolinium(III)}) is a contrast agent for magnetic resonance angiography (MRA). MS-325 consists of two s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f61c279916d9ab9687d5fbb57cefac4
https://doi.org/10.1021/ic700686k
https://doi.org/10.1021/ic700686k
Autor:
Randall B. Lauffer, Thomas J. McMurry, Zhaoda Zhang, Marga Spiller, Matthew T. Greenfield, Peter Caravan
Publikováno v:
Angewandte Chemie International Edition. 44:6766-6769
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a9930a61fffda8dea3040f86056fa4
https://doi.org/10.1002/anie.200502245
https://doi.org/10.1002/anie.200502245
Autor:
Sarah A. McDermid, John C. Amedio, Matthew T. Greenfield, Arnold M. Raitsimring, Peter Caravan, Marga Spiller, Normand J. Cloutier, Randall B. Lauffer, Thomas J. McMurry, Stephen U. Dunham, Stephan G. Zech, Richard J. Looby
Publikováno v:
Chemistry - A European Journal. 11:5866-5874
The synthesis of a novel ligand, based on N-methyl-diethylenetriaminetetraacetate and containing a diphenylcyclohexyl serum albumin binding group (L1) is described and the coordination chemistry and biophysical properties of its Gd(III) complex Gd-L1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf30a66549f61dd180a265b82a46fe9
https://doi.org/10.1002/chem.200500338
https://doi.org/10.1002/chem.200500338
Autor:
Andrea J. Wiethoff, Randall B. Lauffer, Philip B. Graham, Rolf W. Günther, Edward C. Parsons, Elmar Spuentrup, Robert M. Weisskoff, Warren J. Manning, René M. Botnar, Marcus Katoh, Arno Buecker, George Katsimaglis
Publikováno v:
Circulation. 110:1463-1466
Background— The advent of fibrin-binding molecular magnetic resonance (MR) contrast agents and advances in coronary MRI techniques offers the potential for direct imaging of coronary thrombosis. We tested the feasibility of this approach using a ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a88c0a26f631593c3fc3952637ef92
https://doi.org/10.1161/01.cir.0000134960.31304.87
https://doi.org/10.1161/01.cir.0000134960.31304.87
Autor:
Ronald M. Supkowski, William DeW. Horrocks, Richard J. Looby, Thomas J. McMurry, Randall B. Lauffer, Jeff W.M. Bulte, John C. Amedio, Sarah A. McDermid, Normand J. Cloutier, Matthew T. Greenfield, Peter Caravan, Stephen U. Dunham
Publikováno v:
Journal of the American Chemical Society. 124:3152-3162
MS-325 is a novel blood pool contrast agent for magnetic resonance imaging currently undergoing clinical trials to assess blockage in arteries. MS-325 functions by binding to human serum albumin (HSA) in plasma. Binding to HSA serves to prolong plasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ada0ace5b3191a314e80bf237e2b9a9
https://doi.org/10.1021/ja017168k
https://doi.org/10.1021/ja017168k
Autor:
Alexander Nivorozhkin, Peter Caravan, Andrew Kolodziej, Matthew T. Greenfield, Randall B. Lauffer, Thomas J. McMurry
Publikováno v:
Angewandte Chemie. 113:2987-2990
Clinically relevant relaxivity enhancement of a magnetic resonance imaging (MRI) contrast agent has been achieved by using prodrug Gd3+ complexes (see picture, DTPA=diethylenetriaminepentaaceto). Enzymatic cleavage of lysine residues from the prodrug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd8e744b1c32c5fc88da68f96d0f448
https://doi.org/10.1002/1521-3757(20010803)113:15<2987::aid-ange2987>3.0.co
https://doi.org/10.1002/1521-3757(20010803)113:15<2987::aid-ange2987>3.0.co
Autor:
Mark B.M. Hofman, Samuel A. Wickline, Randall B. Lauffer, Stefan Fischer, Kofi Adzamli, Sándor J. Kovács, Robert E. Henson, Jan De Becker, Christine H. Lorenz
Publikováno v:
Magnetic Resonance in Medicine. 41:360-367
The ability of a blood pool contrast agent to enhance MR coronary angiography was defined. The proximal coronary vessels of pigs were imaged before and after administration of Gd-DTPA bound covalently to bovine serum albumin (0.2 mmol/kg). The contra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cc0662486ee8f4bd497542b64cfd715
https://doi.org/10.1002/(sici)1522-2594(199902)41:2<360::aid-mrm21>3.0.co
https://doi.org/10.1002/(sici)1522-2594(199902)41:2<360::aid-mrm21>3.0.co
Publikováno v:
ChemInform. 30
A. Water Exchange 2326 B. Proton Exchange 2327 C. Electronic Relaxation 2327 D. Relaxivity 2331 E. Outerand Second-Sphere Relaxivity 2334 F. Methods of Improving Relaxivity 2336 V. Macromolecular Conjugates 2336 A. Introduction 2336 B. General Conjug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d95463940ce7210d86159fd80f0ac69d
https://doi.org/10.1002/chin.199947322
https://doi.org/10.1002/chin.199947322
Publikováno v:
Magnetic Resonance in Medicine. 17:164-178
Binding of potential blood pool and hepatobiliary paramagnetic iron(III) contrast agents, rac- and meso-Fe(5-Br-EHPG)- (iron(III) N,N'-ethylenebis [(5-bromo-2-hydroxyphenyl)glycinate]) and Fe(5-Br-HBED)- (iron(III) N,N'-bis-(5-bromo-2-hydroxybenzyl)e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7995d23f5608f7fa61d71bad205f0e7
https://doi.org/10.1002/mrm.1910170120
https://doi.org/10.1002/mrm.1910170120