Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Randall, Valerie"'
Autor:
Miranda, Benjamin H., Charlesworth, Matthew R., Tobin, Desmond J., Sharpe, David T., Randall, Valerie A.
Yes
Male sex hormones-androgens-regulate male physique development. Without androgen signaling, genetic males appear female. During puberty, increasing androgens harness the hair follicle's unique regenerative ability to replace many tiny vellus
Male sex hormones-androgens-regulate male physique development. Without androgen signaling, genetic males appear female. During puberty, increasing androgens harness the hair follicle's unique regenerative ability to replace many tiny vellus
Externí odkaz:
http://hdl.handle.net/10454/14146
Autor:
Khidhir, Karzan Ghafur, Woodward, D.F., Farjo, N.P., Farjo, B.K., Tang, E.S., Wang, J.W., Randall, Valerie A., Picksley, Stephen M.
Balding causes widespread psychological distress but is poorly controlled. The commonest treatment, minoxidil, was originally an antihypertensive drug that promoted unwanted hair. We hypothesized that another serendipitous discovery, increased eyelas
Externí odkaz:
http://hdl.handle.net/10454/7237
BACKGROUND: Alopecia causes widespread psychological distress, but is relatively poorly controlled. The development of new treatments is hampered by the lack of suitable human hair follicle models. Although intermediate and vellus hair follicles are
Externí odkaz:
http://hdl.handle.net/10454/6098
Hair disorders cause psychological distress but are generally poorly controlled; more effective treatments are required. Despite the long-standing use of minoxidil for balding, its mechanism is unclear; suggestions include action on vasculature or fo
Externí odkaz:
http://hdl.handle.net/10454/6190
Autor:
Randall, Valerie A., Jenner, Tracey J., Hibberts, Nigel A., De Oliveira, Isabel O., Vafaee, Tayyebeh
Androgens stimulate many hair follicles to alter hair colour and size via the hair growth cycle; in androgenetic alopecia tiny, pale hairs gradually replace large, pigmented ones. Since stem cell factor (SCF) is important in embryonic melanocyte migr
Externí odkaz:
http://hdl.handle.net/10454/6148
Autor:
Hamada, K., Randall, Valerie A.
BACKGROUND: Androgenetic alopecia, or male pattern baldness, is a common, progressive disorder where large, terminal scalp hairs are gradually replaced by smaller hairs in precise patterns until only tiny vellus hairs remain. This balding can cause a
Externí odkaz:
http://hdl.handle.net/10454/3600
Autor:
Davies, Gareth C., Thornton, M. Julie, Jenner, Tracey J., Chen, Yi-Ju, Hansen, J.B., Carr, R.D., Randall, Valerie A.
Although ATP-sensitive potassium (K(ATP)) channel openers, e.g., minoxidil and diazoxide, can induce hair growth, their mechanisms require clarification. Improved drugs are needed clinically. but the absence of a good bioassay hampers research. K(ATP
Externí odkaz:
http://hdl.handle.net/10454/4017
Autor:
Olsen, E.A., Hordinsky, M.K., Price, V.H., Roberts, J.L., Shapiro, J., Canfield, D., Duvic, M., King, L.E. Jr., McMichael, A.J., Randall, Valerie A., Turner, M.L., Sperling, L., Whiting, D.A., Norris, D.
Alopecia areata is an immunologically mediated disease characterized by extreme variability not only in the time of initial onset of hair loss but in the duration, extent and pattern of hair loss during any given episode of active loss. These variabl
Externí odkaz:
http://hdl.handle.net/10454/4042
Red deer stags produce an androgen-dependent mane of long hairs only in the breeding season; in the non-breeding season, when circulating androgen levels are low, the neck hair resembles the rest of the coat. This study was designed to determine whet
Externí odkaz:
http://hdl.handle.net/10454/2946
Autor:
Olsen, Elise A., Hordinsky, Maria K., Price, Vera H., Roberts, Janet L., Shapiro, Jerry, Canfield, Doug, Duvic, Madeleine, King, Lloyd E., Jr., McMichael, Amy J., Randall, Valerie A., Turner, Maria L., Sperling, Leonard, Whiting, David A., Norris, David
Publikováno v:
In Journal of the American Academy of Dermatology 2004 51(3):440-447