Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Randall, Kaye"'
Publikováno v:
Pain Management. 12:25-33
Tolperisone is a nonopioid, centrally acting muscle relaxant in clinical development in the USA for the treatment of symptoms associated with acute, painful muscles spasms of the back. CLN-301, RESUME-1, is a 14-day double-blind, randomized, placebo-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce77adfab952b84a9a2109a7fd8696f2
https://doi.org/10.2217/pmt-2021-0041
https://doi.org/10.2217/pmt-2021-0041
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics
What is known and objective Tolperisone is a centrally acting muscle relaxant under development in the United States as a treatment for acute and painful symptoms of muscle spasms. The objective of this three‐way, randomized, blinded, three‐perio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b089e71a402321e60ed1e1bf01f405ea
https://doi.org/10.1111/jcpt.13165
https://doi.org/10.1111/jcpt.13165
High-throughput screening of chemical libraries is traditionally utilized to identify potential drug candidates. A time-saving alternative to this resource-intensive process is to find new uses for existing drugs. The development of Nuedexta, a combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::522afaee1986b71ea3f4fad0f7263bc6
https://doi.org/10.1016/b978-0-12-816475-4.00001-x
https://doi.org/10.1016/b978-0-12-816475-4.00001-x
Autor:
Karen Aboody, Olubankole Aladesuyi Arogundade, Giovanni Appendino, Weiqi Bao, Marco A.S. Baptista, Danielle Beaulieu, Frank Bennett, Emma Brand, Don Cleveland, Stanley L. Cohan, Jonavelle Cuerdo, Jim DeMesa, David L. Ennist, Meryem Guler, Nada Hindiyeh, Hanna Hovren, Yiyun Henry Huang, Hongmei Jia, Jie Jiang, Brian K. Kaspar, Petra Kaufmann, Randall Kaye, Jeffery W. Kelly, Mike Keymer, Doo Yeon Kim, Kiren Kresa-Reahl, Ikjae Lee, Melanie Leitner, Stefanie N. Linch, Elisabeth B. Lucassen, Timothy Miller, Rachael Mooney, Gaetano Morello, Eduardo Muñoz, Michael Murray, Hoi Wa Ngai, Joseph Park, Dustin Pierce, Jana Portnow, Evan T. Powers, Luisa Quinti, John Ravits, Meghan Romba, Rajesh Sampath, S. Pablo Sardi, Mark Schactman, Mohammad Shahnawaz, Richard A. Smith, Kyle E. Smoot, Claudio Soto, Clive N. Svendsen, Soshana P. Svendsen, Rudolph E. Tanzi, Albert A. Taylor, Gil I. Wolfe, Clinton B. Wright, Gerald Yakatan, Neta Zach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc3421a84af02dbf2e438ec95985c79e
https://doi.org/10.1016/b978-0-12-816475-4.09992-4
https://doi.org/10.1016/b978-0-12-816475-4.09992-4
Publikováno v:
Journal of Pain Research
Objective Use of skeletal muscle relaxants (SMRs) for acute muscle spasm is confounded by central nervous system adverse events (AEs), including somnolence. Tolperisone is an SMR that does not appear to be associated with somnolence. The aim of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d687e95811bf3b066963244cefb4e1c4
https://pubmed.ncbi.nlm.nih.gov/33262641
https://pubmed.ncbi.nlm.nih.gov/33262641
Autor:
Erik P, Pioro, Benjamin Rix, Brooks, Jeffrey, Cummings, Randolph, Schiffer, Ronald A, Thisted, Daniel, Wynn, Adrian, Hepner, Randall, Kaye, Carlos Alejandro, Vrech
Publikováno v:
Annals of Neurology. 68:693-702
Objective: To evaluate dextromethorphan combined with ultra low-dose quinidine (DMq) for treating pseudobulbar affect (PBA) in patients with amyotrophic lateral sclerosis (ALS) or multiple sclerosis (MS). Methods: In a 12-week randomized, double-blin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870ba9b6bb924885e4bc045ed866db64
https://doi.org/10.1002/ana.22093
https://doi.org/10.1002/ana.22093