Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Randal S Tibbetts"'
Autor:
Sang Hwa Kim, Kye D Nichols, Eric N Anderson, Yining Liu, Nandini Ramesh, Weiyan Jia, Connor J Kuerbis, Mark Scalf, Lloyd M Smith, Udai Bhan Pandey, Randal S Tibbetts
Publikováno v:
eLife, Vol 12 (2023)
Mutations in the ubiquitin (Ub) chaperone Ubiquilin 2 (UBQLN2) cause X-linked forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) through unknown mechanisms. Here, we show that aggregation-prone, ALS-associated mutants of U
Externí odkaz:
https://doaj.org/article/72192ff0353948d194af3bd44b77dd3a
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57214 (2013)
Cytosolic aggregation of the nuclear RNA-binding protein TDP-43 is a histopathologic signature of degenerating neurons in amyotrophic lateral sclerosis (ALS), and mutations in the TARDBP gene encoding TDP-43 cause dominantly inherited forms of this c
Externí odkaz:
https://doaj.org/article/c645b9604db14decae0770f39639484e
Autor:
Naval P Shanware, Lihong Zhan, John A Hutchinson, Sang Hwa Kim, Leah M Williams, Randal S Tibbetts
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12173 (2010)
Activating transcription factor 1 (ATF1) and the closely related proteins CREB (cyclic AMP resonse element binding protein) and CREM (cyclic AMP response element modulator) constitute a subfamily of bZIP transcription factors that play critical roles
Externí odkaz:
https://doaj.org/article/70967b6e9d904f0facf833fe18b14c88
Autor:
Sang Hwa Kim, Kye D Nichols, Eric N Anderson, Yining Liu, Nandini Ramesh, Weiyan Jia, Connor J Kuerbis, Mark Scalf, Lloyd M Smith, Udai Bhan Pandey, Randal S Tibbetts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a77aa698625c7c0e8c7654a9322d01a6
https://doi.org/10.7554/elife.84382.sa2
https://doi.org/10.7554/elife.84382.sa2
Autor:
Sang Hwa Kim, Kye D. Nichols, Eric N. Anderson, Yining Liu, Nandini Ramesh, Weiyan Jia, Connor J. Kuerbis, Mark Scalf, Lloyd M. Smith, Udai Bhan Pandey, Randal S. Tibbetts
Mutations in the ubiquitin (Ub) chaperoneUbiquilin 2 (UBQLN2)cause X-linked forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) through unknown mechanisms. Here we show that aggregation-prone, ALS-associated mutants of UBQL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0915a23ffbcce291bacd5fdfb0ccfa0e
https://doi.org/10.1101/2022.10.31.514355
https://doi.org/10.1101/2022.10.31.514355
Autor:
Peter Tonzi, Tony T. Huang, Sang Hwa Kim, Weiyan Jia, Randal S. Tibbetts, Robert J. Milliken, William M. Guns, Adam M. Mastrocola, Lloyd M. Smith, Mark Scalf, Lu Liu
Fused in sarcoma (FUS) encodes a low complexity RNA-binding protein with diverse roles in transcriptional activation and RNA processing. While oncogenic fusions of FUS and transcription factor DNA-binding domains are associated with soft tissue sarco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01734e7f7a6d7f33846bb028f7a9fc1
Autor:
Adam S. Mastrocola, Weiyan Jia, Peter Tonzi, William M. Guns, Lu Liu, Robert J. Millikin, Randal S. Tibbetts, Sang Hwa Kim, Tony T. Huang, Mark Scalf, Lloyd M. Smith
Publikováno v:
The Journal of Biological Chemistry
Fused in sarcoma (FUS) encodes an RNA-binding protein with diverse roles in transcriptional activation and RNA splicing. While oncogenic fusions of FUS and transcription factor DNA-binding domains are associated with soft tissue sarcomas, dominant mu
Publikováno v:
The Journal of Biological Chemistry
The cAMP response element-binding protein (CREB) is an important regulator of cell growth, metabolism, and synaptic plasticity. CREB is activated through phosphorylation of an evolutionarily conserved Ser residue (S133) within its intrinsically disor
Autor:
Anthony T. Trinh, Michele Campaigne Larsen, Pierre R. Bushel, Colin R. Jefcoate, Randal S. Tibbetts, Sang Hwa Kim, Adam S. Mastrocola
Publikováno v:
Nucleic Acids Research
cAMP response element binding protein (CREB) is a key regulator of glucose metabolism and synaptic plasticity that is canonically regulated through recruitment of transcriptional coactivators. Here we show that phosphorylation of CREB on a conserved