Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Randal J. Nonneman"'
Autor:
Domenic H. Cerri, Daniel L. Albaugh, Lindsay R. Walton, Brittany Katz, Tzu-Wen Wang, Tzu-Hao Harry Chao, Weiting Zhang, Randal J. Nonneman, Jing Jiang, Sung-Ho Lee, Amit Etkin, Catherine N. Hall, Garret D. Stuber, Yen-Yu Ian Shih
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract The striatum, known as the input nucleus of the basal ganglia, is extensively studied for its diverse behavioral roles. However, the relationship between its neuronal and vascular activity, vital for interpreting functional magnetic resonanc
Externí odkaz:
https://doaj.org/article/7f2843290a2d4421b7c9e76dab4e7dfd
Autor:
Paola Giusti-Rodríguez, James G. Xenakis, James J. Crowley, Randal J. Nonneman, Daniela M. DeCristo, Allison Ryan, Corey R. Quackenbush, Darla R. Miller, Ginger D. Shaw, Vasyl Zhabotynsky, Patrick F. Sullivan, Fernando Pardo Manuel de Villena, Fei Zou
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 3165-3177 (2020)
Schizophrenia is an idiopathic disorder that affects approximately 1% of the human population, and presents with persistent delusions, hallucinations, and disorganized behaviors. Antipsychotics are the standard pharmacological treatment for schizophr
Externí odkaz:
https://doaj.org/article/5f8d499338a344dbb93bdab1443f738f
Autor:
Andrew P. Morgan, Chen-Ping Fu, Chia-Yu Kao, Catherine E. Welsh, John P. Didion, Liran Yadgary, Leeanna Hyacinth, Martin T. Ferris, Timothy A. Bell, Darla R. Miller, Paola Giusti-Rodriguez, Randal J. Nonneman, Kevin D. Cook, Jason K. Whitmire, Lisa E. Gralinski, Mark Keller, Alan D. Attie, Gary A. Churchill, Petko Petkov, Patrick F. Sullivan, Jennifer R. Brennan, Leonard McMillan, Fernando Pardo-Manuel de Villena
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 2, Pp 263-279 (2016)
Genotyping microarrays are an important resource for genetic mapping, population genetics, and monitoring of the genetic integrity of laboratory stocks. We have developed the third generation of the Mouse Universal Genotyping Array (MUGA) series, Gig
Externí odkaz:
https://doaj.org/article/7b77e12c8fb14a99aaee429fcfb94338
Autor:
Domenic H. Cerri, Daniel L. Albaugh, Lindsay R. Walton, Brittany Katz, Tzu-Wen Wang, Tzu-Hao Harry Chao, Weiting Zhang, Randal J. Nonneman, Jing Jiang, Sung-Ho Lee, Amit Etkin, Catherine N. Hall, Garret D. Stuber, Yen-Yu Ian Shih
SummaryThe striatum is the primary input nucleus of the basal ganglia, widely studied for its complex roles in health and disease. Functional magnetic resonance imaging (fMRI) studies are essential for discerning striatal function, however the relati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a41f945f2a4a418491e7d25d7ef3bc41
https://doi.org/10.1101/2023.02.20.529283
https://doi.org/10.1101/2023.02.20.529283
Autor:
Andrew P Morgan, James J Crowley, Randal J Nonneman, Corey R Quackenbush, Cheryl N Miller, Allison K Ryan, Molly A Bogue, Sur Herrera Paredes, Scott Yourstone, Ian M Carroll, Thomas H Kawula, Maureen A Bower, R Balfour Sartor, Patrick F Sullivan
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115225 (2014)
The second-generation antipsychotic olanzapine is effective in reducing psychotic symptoms but can cause extreme weight gain in human patients. We investigated the role of the gut microbiota in this adverse drug effect using a mouse model. First, we
Externí odkaz:
https://doaj.org/article/6b50b2b12320446f8700e0bed06565e1
Autor:
Jessica S. Johnson, Peter Holmans, Patrick F. Sullivan, Elliott Rees, Menachem Fromer, Sarah E. Bergen, NaEshia Ancalade, Michael Conlon O'Donovan, Jin P. Szatkiewicz, Douglas M. Ruderfer, Michael J. Owen, Eli A. Stahl, James J. Crowley, George Kirov, Christina M. Hultman, Shaun Purcell, Randal J. Nonneman, Pamela Sklar
Publikováno v:
Biol Psychiatry
Genetic studies of schizophrenia (SCZ) have now implicated numerous genomic loci that contribute to risk including several copy number variants (CNV) of large effect and hundreds of associated loci of small effect. However, in only a few cases has a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004c8be74b492ddfbc250fd353e0663f
https://europepmc.org/articles/PMC7103483/
https://europepmc.org/articles/PMC7103483/
Autor:
Petko M. Petkov, John P. Didion, Gary A. Churchill, Patrick F. Sullivan, Paola Giusti-Rodríguez, J. Brennan, Kevin D. Cook, Lisa E. Gralinski, Fernando Pardo-Manuel de Villena, Darla R. Miller, Liran Yadgary, Alan D. Attie, Leeanna Hyacinth, Randal J. Nonneman, Martin T. Ferris, Andrew P. Morgan, Timothy A. Bell, Chen Ping Fu, Leonard McMillan, Mark P. Keller, Jason K. Whitmire, Chia-Yu Kao, Catherine E. Welsh
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 2, Pp 263-279 (2016)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Genotyping microarrays are an important resource for genetic mapping, population genetics, and monitoring of the genetic integrity of laboratory stocks. We have developed the third generation of the Mouse Universal Genotyping Array (MUGA) series, Gig
Autor:
Toni Ahtoniemi, Randal J. Nonneman, Natallia V. Riddick, Matthew L. Hirsch, Thomas G. Hampton, Catherine F. Dial, Hillarie P. Windish, Isabelle Richard, Nadia Nagy, Telmo Llanga, Jukka Puoliväli, Douglas E. Albrecht, Kimmo Lehtimäki, Sheryl S. Moy
Publikováno v:
Physiological Reports
Physiological Reports, Wiley, 2017, 5 (6), pp.e13173. ⟨10.14814/phy2.13173⟩
Physiological Reports, 2017, 5 (6), pp.e13173. ⟨10.14814/phy2.13173⟩
Physiological Reports, Wiley, 2017, 5 (6), pp.e13173. ⟨10.14814/phy2.13173⟩
Physiological Reports, 2017, 5 (6), pp.e13173. ⟨10.14814/phy2.13173⟩
International audience; The identification of a dysferlin-deficient animal model that accurately displays both the physiological and behavior aspects of human dysferlinopathy is critical for the evaluation of potential therapeutics. Disease progressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ad92203428577dc406ffa60a99822e
https://hal.archives-ouvertes.fr/hal-02333051
https://hal.archives-ouvertes.fr/hal-02333051
Autor:
Sheryl S. Moy, Natallia V. Riddick, Viktoriya D. Nikolova, Jessica J. Nadler, Randal J. Nonneman, Brian L. Teng, Kara L. Agster, James W. Bodfish, Nancy B. Young, Lorinda K. Baker
Publikováno v:
Behavioural Brain Research. 259:200-214
Restricted repetitive behaviors are core symptoms of autism spectrum disorders (ASDs). The range of symptoms encompassed by the repetitive behavior domain includes lower-order stereotypy and self-injury, and higher-order indices of circumscribed inte
Autor:
Natallia V. Riddick, Sheryl S. Moy, Darin J. Knapp, Geoffrey O. Shafer, Viktoriya D. Nikolova, Lorinda K. Baker, Kara L. Agster, Randal J. Nonneman
Publikováno v:
Neurotoxicology and Teratology. 36:36-46
Autism is a severe neurodevelopmental disorder, diagnosed on the basis of core behavioral symptoms. Although the mechanistic basis for the disorder is not yet known, genetic analyses have suggested a role for abnormal excitatory/inhibitory signaling