Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Randa El-Zein"'
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 8499-8509 (2023)
Abstract Background Unlike normal cells, cancer cells frequently have multiple centrosomes that can cluster to form bipolar mitotic spindles and allow for successful cell division. Inhibiting centrosome clustering, therefore, holds therapeutic promis
Externí odkaz:
https://doaj.org/article/aa0ad6a5ec3b4d57a412fe08bf7f16ef
Autor:
Brandon Mistretta, Sakuni Rankothgedera, Micah Castillo, Mitchell Rao, Kimberly Holloway, Anjana Bhardwaj, Maha El Noafal, Constance Albarracin, Randa El-Zein, Hengameh Rezaei, Xiaoping Su, Rehan Akbani, Xiaoshan M. Shao, Brian J. Czerniecki, Rachel Karchin, Isabelle Bedrosian, Preethi H. Gunaratne
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionWe present here a strategy to identify immunogenic neoantigen candidates from unique amino acid sequences at the junctions of fusion proteins which can serve as targets in the development of tumor vaccines for the treatment of breastcance
Externí odkaz:
https://doaj.org/article/4ec9e2ca15084d978b27a5af1c2c1793
Autor:
Jose Thaiparambil, Jianrong Dong, Sandra L. Grimm, Dimuthu Perera, Chandra Shekar R. Ambati, Vasanta Putluri, Matthew J. Robertson, Tajhal D. Patel, Brandon Mistretta, Preethi H. Gunaratne, Min P. Kim, Jason T. Yustein, Nagireddy Putluri, Cristian Coarfa, Randa El‐Zein
Publikováno v:
Cancer Medicine, Vol 12, Iss 1, Pp 584-596 (2023)
Abstract Background Non‐small cell lung cancer (NSCLC) comprises the majority (~85%) of all lung tumors, with lung adenocarcinoma (LUAD) and squamous cell carcinoma (LUSC) being the most frequently diagnosed histological subtypes. Multi‐modal omi
Externí odkaz:
https://doaj.org/article/446a9373295047ea962bd5f2c349b9b6
Autor:
Emma C. Bowers, Alexandre M. Cavalcante, Kimberly Nguyen, Can Li, Yingshan Wang, Randa El-Zein, Shu-Hsia Chen, Min P. Kim, Brian S. McKay, Kenneth S. Ramos
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1169 (2024)
Aberrant expression of the oncogenic retrotransposon LINE-1 is a hallmark of various cancer types, including non-small cell lung cancers (NSCLCs). Here, we present proof-of-principle evidence that LINE-1 analytes in extracellular vesicles (EVs) serve
Externí odkaz:
https://doaj.org/article/84ab0243014145e1bac65d7c845bbfc8
Autor:
Hui Li, Kayla Robinson, Li Lan, Natalie Baughan, Chun-Wai Chan, Matthew Embury, Gary J. Whitman, Randa El-Zein, Isabelle Bedrosian, Maryellen L. Giger
Publikováno v:
Cancers, Vol 15, Iss 7, p 2141 (2023)
The identification of women at risk for sporadic breast cancer remains a clinical challenge. We hypothesize that the temporal analysis of annual screening mammograms, using a long short-term memory (LSTM) network, could accurately identify women at r
Externí odkaz:
https://doaj.org/article/460bcb8f73f0480697fa9e42e25bbdc8
Autor:
Maggie Britton, Tzuan A. Chen, Isabel Martinez Leal, Anastasia Rogova, Bryce Kyburz, Teresa Williams, Mayuri Patel, Randa El-Zein, Eric H. Bernicker, Lisa M. Lowenstein, Lorraine R. Reitzel
Publikováno v:
Cancers, Vol 15, Iss 7, p 2073 (2023)
For people at elevated risk for lung cancer, lung cancer screening (LCS) reduces lung cancer mortality. People with non-nicotine substance use disorders (SUDs) have elevated rates of smoking compared with the general population, highlighting them as
Externí odkaz:
https://doaj.org/article/d325b712b88b4719b75fb97348559a94
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 15 (2021)
Background: Inflammatory breast cancer (IBC) is a rare form of breast cancer with a poor prognosis. IBC is characterized by florid lymphovascular tumor emboli in the skin and the parenchyma of the breast. We hypothesized that the formation of these e
Externí odkaz:
https://doaj.org/article/85e536b6d588406b8ddb433c5c811c25
Autor:
Tamer M Fouad, Naoto T Ueno, Robert K Yu, Joe E Ensor, Ricardo H Alvarez, Savitri Krishnamurthy, Anthony Lucci, James M Reuben, Wei Yang, Jie S Willey, Vicente Valero, Melissa L Bondy, Massimo Cristofinalli, Sanjay Shete, Wendy A Woodward, Randa El-Zein
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204372 (2018)
BACKGROUND:To date, studies on inflammatory breast cancer (IBC) lack comprehensive epidemiological data. We analyzed detailed prospectively collected clinical and epidemiological data from the IBC Registry at The University of Texas MD Anderson Cance
Externí odkaz:
https://doaj.org/article/8511d62dbc0747a2b9551bb1c21892e1
Autor:
Arvind Bambhroliya, Renae D Van Wyhe, Swaminathan Kumar, Bisrat G Debeb, Jay P Reddy, Steve Van Laere, Randa El-Zein, Arvind Rao, Wendy A Woodward
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0192689 (2018)
Epidemiological studies have found that triple-negative breast cancer (TNBC) and TN inflammatory breast cancer (IBC) are associated with lower frequency and duration of breast-feeding compared to non-TNBC and non-TN IBC, respectively. Limited breast-
Externí odkaz:
https://doaj.org/article/efbff8ff0f33420eae9866eddb6bde68
Autor:
Chengcheng Guo, Haibo Lu, Wen Gao, Li Wang, Kaihua Lu, Shuhong Wu, Apar Pataer, Maosheng Huang, Randa El-Zein, Tongyu Lin, Jack A Roth, Reza Mehran, Wayne Hofstetter, Stephen G Swisher, Xifeng Wu, Bingliang Fang
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74973 (2013)
We recently showed that IGFBP2 is overexpressed in primary lung cancer tissues. This study aims to determine whether IGFBP2 is elevated in blood samples of lung cancer patients and whether its level is associated with clinical outcomes.Plasma IGFBP2
Externí odkaz:
https://doaj.org/article/803ef1607e1a448087357c4841b43520