Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Randa E Abdel-Megeid"'
Publikováno v:
Molecules, Vol 19, Iss 5, Pp 5459-5469 (2014)
4-Imino-1-p-tolyl-1,4-dihydropyrazolo[3,4-d]pyrimidin-5-ylamine (2) and (1-p-tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-hydrazine (3) were prepared starting from ethyl 4-cyano-1-p-tolyl-1H-pyrazol-5-ylimidoformate (1). The structure of compound 3 was co
Externí odkaz:
https://doaj.org/article/43167983071e4a3d98893aca1f24cb0b
Publikováno v:
Archiv der Pharmazie. 347:559-565
5-Amino-1-p-tolyl-1H-pyrazole-4-carbonitrile (1) was used for the preparation of some novel pyrazoles and pyrazolo[3,4-d]pyrimidines 2-10. Moreover, the cytotoxicity and in vitro anticancer activities of the prepared compounds were also assessed agai
Publikováno v:
Molecules
Volume 19
Issue 5
Pages: 5459-5469
Molecules, Vol 19, Iss 5, Pp 5459-5469 (2014)
Volume 19
Issue 5
Pages: 5459-5469
Molecules, Vol 19, Iss 5, Pp 5459-5469 (2014)
4-Imino-1-p-tolyl-1,4-dihydropyrazolo[3,4-d]pyrimidin-5-ylamine (2) and (1-p-tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-hydrazine (3) were prepared starting from ethyl 4-cyano-1-p-tolyl-1H-pyrazol-5-ylimidoformate (1). The structure of compound 3 was co
Autor:
Aymn E. Rashad, Ahmed H. Shamroukh, Randa E. Abdel-Megeid, Klaus Banert, Ahmed Mostafa, Mohamed A. Ali
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 29:809-820
Treatment of 5-amino-1-(9-methyl-5,6-dihydronaphtho[1',2':4,5]thieno[2,3-d]pyrimidin-11-yl)-1H-pyrazole-4-carbonitrile (1) with formic acid afforded pyrazolo[3,4-d]pyrimidin-4-one derivative 2. The sodium salt of the latter compound (generated in sit
Publikováno v:
Synthetic Communications. 40:1149-1160
Some novel indeno[2,1-b]thiophenes, indeno[1′,2′:4,5]thieno[2,3-d][1,2,3]triazines, indeno[1′,2′:4,5]thieno[2,3-d]pyrimidines, indeno[1′,2′:4,5]thieno[2,3-d][1,3]thiazolo[3,2-a]pyrimidines, and indeno[1′,2′:4,5]thieno[2,3-d][1,2,4]tri
Autor:
Aymn E. Rashad, Farouk M. E. Abdel-Megeid, Mamdouh M. Ali, Mohamed I. Hegab, Randa E. Abdel-Megeid
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 185:74-83
A series of novel pyrazolo[3,4-d]pyrimidine 2b, 3, 5b, pyrazolotetrazolopyrimidine 4, and pyrazolotriazolopyrimidine derivatives 6a,b–10a,b have been synthesized and characterized by elemental analysis and spectroscopic data. Furthermore, the cytot
Autor:
Mohamed I. Hegab, Aymn E. Rashad, Randa E. Abdel-Megeid, Farouk M. E. Abdel-Megeid, Jehan A. Micky
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:7102-7106
Some novel substituted pyrazole and pyrazolo[3,4-d]pyrimidine derivatives 2, 4, 8, and 9 were synthesized. Also, some acyclic S-nucleosides of pyrazolo[3,4-d]pyrimidine derivatives 10–13 were prepared via reaction of pyrazolo[3,4-d]pyrimidine-4(3H)
Publikováno v:
ChemInform. 41
A variety of novel polycondensed thienopyrimidine derivatives are synthesized starting from 2-aminoindenothiophene-3-carboxylic amide (I).
Publikováno v:
Archives of pharmacal research. 34(7)
New 1-[(tetrazol-5-yl)methyl]indole derivatives, their acyclic nucleoside analogs and the corresponding glycoside derivatives were synthesized. Furthermore, the [)(1,2,4-triazol-3-yl)methyl])-2H-tetrazole derivative as well as the corresponding thiog
Autor:
Mohamed A. Ali, Ahmed Mostafa, Ahmed H. Shamroukh, Randa E. Abdel-Megeid, Ahmed Kandeil, Rabeh El-Shesheny, Klaus Banert, Aymn E. Rashad
Publikováno v:
European journal of medicinal chemistry. 45(11)
Several derivatives containing dihydronaphtho, naphtho[2,1-b]thiophene and thieno[2,3-d]pyrimidine ring systems were prepared starting from 2-amino-4,5-dihydronaphtho[2,1-b]thiophene-1-carbonitrile (1). Structure characterization of the thioxo deriva