Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Randa Abdel Malik"'
Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis
Autor:
Beate Fisslthaler, Nina Zippel, Randa Abdel Malik, Fredy Delgado Lagos, Sven Zukunft, Janina Thoele, Daniel Siuda, Oliver Soehnlein, Ilka Wittig, Juliana Heidler, Andreas Weigert, Ingrid Fleming
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 12, p 3005 (2019)
The AMP-activated protein kinase (AMPK) is an energy sensing kinase that is activated by a drop in cellular ATP levels. Although several studies have addressed the role of the AMPKα1 subunit in monocytes and macrophages, little is known about the α
Externí odkaz:
https://doaj.org/article/4663e5abc50b481b9a102b9411365e32
Autor:
Lunda Gu, Juliane Hitzel, Franziska Moll, Christoph Kruse, Randa Abdel Malik, Jens Preussner, Mario Looso, Matthias S Leisegang, Dieter Steinhilber, Ralf P Brandes, Christian Fork
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146645 (2016)
Epigenetic marks critically control gene expression and thus the cellular activity state. The functions of many epigenetic modifiers in the vascular system have not yet been studied. We screened for histone modifiers in endothelial cells and observed
Externí odkaz:
https://doaj.org/article/61fc4cc192fe4c20af5d77d442791cb2
Autor:
Christoph Schürmann, Juliana Heidler, Sofia Iris Bibli, Fragiska Sigala, Voahanginirina Randriamboavonjy, Bert Luck, Sven Zukunft, Ralf P. Brandes, Csaba Szabó, Andreas Papapetropoulos, Diamantis I. Tsilimigras, Mauro Siragusa, Daniel Siuda, Janina Wittig, Konstantinos Filis, Josef Pfeilschifter, Dao Wen Wang, Jiong Hu, George C. Zografos, Chen Chen, Randa Abdel Malik, Baktybek Kojonazarov, Ingrid Fleming, Ilka Wittig
Publikováno v:
Circulation. 139:101-114
Background: Hydrogen sulfide (H 2 S), generated by cystathionine γ lyase (CSE), is an important endogenous regulator of vascular function. The aim of the present study was to investigate the control and consequences of CSE activity in endothelial ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1b4586c7c1292be70fe2d49ebe679e
https://doi.org/10.1161/circulationaha.118.034757
https://doi.org/10.1161/circulationaha.118.034757
Autor:
Khader Awwad, Rüdiger Popp, Nina Zippel, Josef Pfeilschifter, Lei Shi, Nicole Mangels, Jiong Hu, Beate Fisslthaler, Ingrid Fleming, Johannes A. Eble, Randa Abdel Malik
Publikováno v:
Cardiovascular Research. 106:284-294
Aims Secreted modular calcium-binding protein 1 (SMOC1) is a matricellular protein that potentially interferes with growth factor receptor signalling. The aim of this study was to determine how its expression is regulated in endothelial cells and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ee7e61d933622f20d5a06db6e26f8f
https://doi.org/10.1093/cvr/cvv098
https://doi.org/10.1093/cvr/cvv098
Autor:
Bernhard Brüne, Susanne Wingert, Amro Elgheznawy, Joana Zink, Rolf Bremer, Andreas Weigert, Michael A. Rieger, Lea Günther, Christoph Schürmann, Peter M. Benz, Ralf P. Brandes, Sabrina Bothur, Hebatullah Laban, Ingrid Fleming, Randa Abdel Malik
Publikováno v:
The Journal of Cell Biology
In ischemic vascular diseases, leukocyte recruitment and polarization are crucial for revascularization and tissue repair. The study of Laban et al. provides evidence that VASP is a major regulator of leukocyte recruitment and polarization and vascul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7671cf7e776ca603d21c881eb6000bd7
https://pubmed.ncbi.nlm.nih.gov/29507126
https://pubmed.ncbi.nlm.nih.gov/29507126
Autor:
Susanne Wingert, Timo Frömel, Ingrid Fleming, Beate Fisslthaler, Juliana Heidler, Sven Zukunft, Nariman Ansari, Nina Zippel, Barbara Walzog, Ilka Wittig, Michael A. Rieger, Francesco Pampaloni, Randa Abdel Malik
Publikováno v:
Circulation research. 120(1)
Rationale: The AMP-activated protein kinase (AMPK) is stimulated by hypoxia, and although the AMPKα1 catalytic subunit has been implicated in angiogenesis, little is known about the role played by the AMPKα2 subunit in vascular repair. Objective: T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e72f0fc080fa5921ce2961d20bb79dd
https://pubmed.ncbi.nlm.nih.gov/28057780
https://pubmed.ncbi.nlm.nih.gov/28057780
Autor:
Ralf P. Brandes, Randa Abdel Malik, Jens Preussner, Lunda Gu, Christoph Kruse, Franziska Moll, Dieter Steinhilber, Mario Looso, Christian Fork, Matthias S. Leisegang, Juliane Hitzel
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 1, p e0146645 (2016)
PLoS ONE, Vol 11, Iss 1, p e0146645 (2016)
Epigenetic marks critically control gene expression and thus the cellular activity state. The functions of many epigenetic modifiers in the vascular system have not yet been studied. We screened for histone modifiers in endothelial cells and observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c66f2b251e01f6a3ebfcfada504716
https://publica.fraunhofer.de/handle/publica/257288
https://publica.fraunhofer.de/handle/publica/257288
