Caspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasion.

Autor: Podmirseg SR; Division of Medical Biochemistry; Biocenter; Innsbruck Medical University; Innsbruck, Austria., Jäkel H; Division of Medical Biochemistry; Biocenter; Innsbruck Medical University; Innsbruck, Austria., Ranches GD; Division of Medical Biochemistry; Biocenter; Innsbruck Medical University; Innsbruck, Austria., Kullmann MK; Division of Medical Biochemistry; Biocenter; Innsbruck Medical University; Innsbruck, Austria., Sohm B; Laboratoire Interdisciplinaire des Environnements Continentaux (LIEC), UMR 7360, Université de Lorraine, Metz, France.; CNRS, LIEC, UMR 7360, Metz, France., Villunger A; Division of Developmental Immunology; Biocenter; Innsbruck Medical University; Innsbruck, Austria.; Tyrolean Cancer Research Institute, Innsbruck, Austria., Lindner H; Division of Clinical Biochemistry; Biocenter; Innsbruck Medical University; Innsbruck, Austria., Hengst L; Division of Medical Biochemistry; Biocenter; Innsbruck Medical University; Innsbruck, Austria.

Publikováno v: Oncogene [Oncogene] 2016 Sep 01; Vol. 35 (35), pp. 4580-90. Date of Electronic Publication: 2016 Feb 01.