Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ranajeet S Saund"'
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0186275 (2017)
Ewing sarcoma is a bone malignancy of children and young adults, frequently harboring the EWS/FLI chromosomal translocation. The resulting fusion protein is an aberrant transcription factor that uses highly repetitive GGAA-containing elements (micros
Externí odkaz:
https://doaj.org/article/0e5dd21fb6a94abeb452ffac48459372
Autor:
Stephen L. Lessnick, Sunil Sharma, David F. Callen, Mary C. Beckerle, Olivier Delattre, Jaume Mora, Franck Tirode, Elizabeth R. Lawlor, Brian D. Crompton, Ioana L. Pop, Ranajeet S. Saund, Kirsten M. Johnson, Emily R. Theisen, Cenny Taslim, Christina D. Drenberg, Kathleen I. Pishas
GSK-LSD1, Doxorubicin and AraC have no effect on KDM1A and KDM1B expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1051ce09797e7b498c067f204794a86
https://doi.org/10.1158/1535-7163.22509571.v1
https://doi.org/10.1158/1535-7163.22509571.v1
Autor:
Stephen L. Lessnick, Sunil Sharma, David F. Callen, Mary C. Beckerle, Olivier Delattre, Jaume Mora, Franck Tirode, Elizabeth R. Lawlor, Brian D. Crompton, Ioana L. Pop, Ranajeet S. Saund, Kirsten M. Johnson, Emily R. Theisen, Cenny Taslim, Christina D. Drenberg, Kathleen I. Pishas
Protein expression of ER-stress response genes following treatment with SP-2509
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0388e4ca3b246780959d79b84a856ff2
https://doi.org/10.1158/1535-7163.22509565.v1
https://doi.org/10.1158/1535-7163.22509565.v1
Autor:
Stephen L. Lessnick, Sunil Sharma, David F. Callen, Mary C. Beckerle, Olivier Delattre, Jaume Mora, Franck Tirode, Elizabeth R. Lawlor, Brian D. Crompton, Ioana L. Pop, Ranajeet S. Saund, Kirsten M. Johnson, Emily R. Theisen, Cenny Taslim, Christina D. Drenberg, Kathleen I. Pishas
Targeted KDM1A inhibition and EWS/FLI knockdown induces similar transcriptional signatures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43708ed7fd5e4213822a969dd241bbbf
https://doi.org/10.1158/1535-7163.22509577
https://doi.org/10.1158/1535-7163.22509577
Autor:
Stephen L. Lessnick, Sunil Sharma, David F. Callen, Mary C. Beckerle, Olivier Delattre, Jaume Mora, Franck Tirode, Elizabeth R. Lawlor, Brian D. Crompton, Ioana L. Pop, Ranajeet S. Saund, Kirsten M. Johnson, Emily R. Theisen, Cenny Taslim, Christina D. Drenberg, Kathleen I. Pishas
Hypersensitive SP-2509 cell lines display similar transcriptomic profiles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e17f939c8c1e534cd2c8eaf60fb9562
https://doi.org/10.1158/1535-7163.22509568.v1
https://doi.org/10.1158/1535-7163.22509568.v1
Autor:
Stephen L. Lessnick, Sunil Sharma, David F. Callen, Mary C. Beckerle, Olivier Delattre, Jaume Mora, Franck Tirode, Elizabeth R. Lawlor, Brian D. Crompton, Ioana L. Pop, Ranajeet S. Saund, Kirsten M. Johnson, Emily R. Theisen, Cenny Taslim, Christina D. Drenberg, Kathleen I. Pishas
Cell line source/culture conditions, primer/shRNA sequences, antibodies utilized in this study and additional methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a730c92e76e8d6e5c012ae04934f7d3
https://doi.org/10.1158/1535-7163.22509559
https://doi.org/10.1158/1535-7163.22509559
Autor:
Stephen L. Lessnick, Sunil Sharma, David F. Callen, Mary C. Beckerle, Olivier Delattre, Jaume Mora, Franck Tirode, Elizabeth R. Lawlor, Brian D. Crompton, Ioana L. Pop, Ranajeet S. Saund, Kirsten M. Johnson, Emily R. Theisen, Cenny Taslim, Christina D. Drenberg, Kathleen I. Pishas
Validation of KDM1A knockdown in Ewing sarcoma cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46aec94be9920dac3b2aee9af9cda637
https://doi.org/10.1158/1535-7163.22509580
https://doi.org/10.1158/1535-7163.22509580
Autor:
Stephen L. Lessnick, Sunil Sharma, David F. Callen, Mary C. Beckerle, Olivier Delattre, Jaume Mora, Franck Tirode, Elizabeth R. Lawlor, Brian D. Crompton, Ioana L. Pop, Ranajeet S. Saund, Kirsten M. Johnson, Emily R. Theisen, Cenny Taslim, Christina D. Drenberg, Kathleen I. Pishas
Multi-agent chemotherapeutic regimes remain the cornerstone treatment for Ewing sarcoma, the second most common bone malignancy diagnosed in pediatric and young adolescent populations. We have reached a therapeutic ceiling with conventional cytotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36dadafa9852d23357beb019700fb0a2
https://doi.org/10.1158/1535-7163.c.6539329
https://doi.org/10.1158/1535-7163.c.6539329
Autor:
Stephen L. Lessnick, Sunil Sharma, David F. Callen, Mary C. Beckerle, Olivier Delattre, Jaume Mora, Franck Tirode, Elizabeth R. Lawlor, Brian D. Crompton, Ioana L. Pop, Ranajeet S. Saund, Kirsten M. Johnson, Emily R. Theisen, Cenny Taslim, Christina D. Drenberg, Kathleen I. Pishas
Cytotoxic effects of the irreversible KDM1A inhibitors GSK-LSD1 and Tranylcypromine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6857cc5656e80f4f3cb68d0e124a39c1
https://doi.org/10.1158/1535-7163.22509574
https://doi.org/10.1158/1535-7163.22509574
Publikováno v:
Oncotarget
// Emily R. Theisen 1,* , Kathleen I. Pishas 1,2,* , Ranajeet S. Saund 1,* and Stephen L. Lessnick 1,3 1 Center for Childhood Cancer and Blood Disorders, The Research Institute at Nationwide Children’s Hospital, Columbus, Ohio, USA 2 Cancer Therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5e5cb3529e3964d25dbb8fb9aedded
https://doi.org/10.18632/oncotarget.7124
https://doi.org/10.18632/oncotarget.7124