Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ranadheer Ravula"'
Autor:
Zhining Wen, Zhijun Wang, Steven Wang, Ranadheer Ravula, Lun Yang, Jun Xu, Charles Wang, Zhong Zuo, Moses S S Chow, Leming Shi, Ying Huang
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18278 (2011)
To pursue a systematic approach to discovery of mechanisms of action of traditional Chinese medicine (TCM), we used microarrays, bioinformatics and the "Connectivity Map" (CMAP) to examine TCM-induced changes in gene expression. We demonstrated that
Externí odkaz:
https://doaj.org/article/9a715bcc80a34e4988970775b2235cd4
Autor:
Leming Shi, Yunjie Song, Zhijun Wang, Steven Yeung, Christopher W.K. Lam, Bernard Lau, Jijun Hao, Jeffrey Wang, Mandy Liu, Ranadheer Ravula, Ying Huang, Moses S. S. Chow
Publikováno v:
Oncotarget
// Zhijun Wang 1 , Ranadheer Ravula 2 , Leming Shi 3 , Yunjie Song 3 , Steven Yeung 1 , Mandy Liu 2 , Bernard Lau 1 , Jijun Hao 4 , Jeffrey Wang 2 , Christopher Wai Kei Lam 5 , Moses Sing Sum Chow 1 , Ying Huang 2 1 Center for Advancement of Drug Res
Publikováno v:
Current Drug Discovery Technologies. 7:54-66
The main cause of failure in cancer drug therapy is the emergence of cellular resistance to drugs. Cancer cells, after exposure to one drug, can become simultaneously insensitive to mechanistically and chemically unrelated drugs, a phenotype known as
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 332:949-958
The x c − cystine/glutamate antiporter has been implicated in GSH-based chemoresistance because it mediates cellular uptake of cystine/cysteine for sustenance of intracellular GSH levels. Celastrol, isolated from a Chinese medicinal herb, is a nove
Publikováno v:
Drug development and industrial pharmacy. 42(6)
Conventional pain management approaches have limitations such as gastrointestinal side effects, frequent dosing, and difficulties in swallowing medications. Hence, to overcome these limitations, we developed a transdermal analgesic patch.This study w
Autor:
Zhong Zuo, Leming Shi, Ying Huang, Lun Yang, Zhining Wen, Ranadheer Ravula, Moses S. S. Chow, Jun Xu, Steven Wang, Charles Wang, Zhijun Wang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 3, p e18278 (2011)
PLoS ONE, Vol 6, Iss 3, p e18278 (2011)
To pursue a systematic approach to discovery of mechanisms of action of traditional Chinese medicine (TCM), we used microarrays, bioinformatics and the "Connectivity Map" (CMAP) to examine TCM-induced changes in gene expression. We demonstrated that
Publikováno v:
Cancer Research. 70:1534-1534
Multi-drug resistance (MDR) is an obstacle for therapeutic success of anticancer agents. Overexpression of P-glycoprotein (P-gp), encoded by ABCB1 gene, plays a key role in conferring MDR via active efflux of anticancer drugs from cells. Previous eff
Autor:
Sunil Prabhu, Bradley T. Andresen, Moses Ss Chow, Ying Huang, Zhijun Wang, Mandy Liu, Ranadheer Ravula, Arvind Thakkar, Zhong Zuo
Publikováno v:
Cell & Bioscience
Background Induction of Nrf2-mediated detoxifying/antioxidant genes has been recognized as an effective strategy for cancer chemoprevention. Si-Wu-Tang (SWT), comprising the combination of four herbs, Paeoniae, Angelicae, Chuanxiong and Rehmanniae, i