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A frog‐derived antimicrobial peptide as a potential anti‐biofilm agent in combating Staphylococcus aureus skin infection

Autor: Fan Fei, Tao Wang, Yangyang Jiang, Xiaoling Chen, Chengbang Ma, Mei Zhou, Qinan Wu, Peng Cao, Jinao Duan, Tianbao Chen, James F. Burrows, Lei Wang

Publikováno v: Fei, F, Wang, T, Jiang, Y, Chen, X, Ma, C, Zhou, M, Wu, Q, Cao, P, Duan, J, Chen, T, Burrows, J F & Wang, L 2023, ' A frog-derived antimicrobial peptide as a potential anti-biofilm agent in combating Staphylococcus aureus skin infection ', Journal of Cellular and Molecular Medicine . https://doi.org/10.1111/jcmm.17785

Staphylococcus aureus (S. aureus), one of the most prevalent bacteria found in atopic dermatitis lesions, can induce ongoing infections and inflammation by downregulating the expression of host defence peptides in the skin. In addition, the emergence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e411accce7b1ee9c1404f11d1ceddac
https://pure.qub.ac.uk/en/publications/60247115-d1c3-490f-8229-06bad8013c03

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Akademický článek

Modification Targeting the 'Rana Box' Motif of a Novel Nigrocin Peptide From Hylarana latouchii Enhances and Broadens Its Potency Against Multiple Bacteria

Autor: Kaifan Bao, Weiyuan Yuan, Chengbang Ma, Xi Yu, Lei Wang, Min Hong, Xinping Xi, Mei Zhou, Tianbao Chen

Publikováno v: Frontiers in Microbiology, Vol 9 (2018)

Public health is confronting the threat caused by antibiotic resistance and this means new antibacterial strategies must be developed urgently. Antimicrobial peptides (AMPs) have been considered as promising therapeutic candidates against infection i

Externí odkaz: https://doaj.org/article/79e5387a1b5a4041bb98a7527ff01cc1

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Akademický článek

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Akademický článek

Novel Antimicrobial Peptides from the Arctic Polychaeta Nicomache minor Provide New Molecular Insight into Biological Role of the BRICHOS Domain

Autor: Pavel V. Panteleev, Andrey V. Tsarev, Ilia A. Bolosov, Alexander S. Paramonov, Mariana B. Marggraf, Sergey V. Sychev, Zakhar O. Shenkarev, Tatiana V. Ovchinnikova

Publikováno v: Marine Drugs, Vol 16, Iss 11, p 401 (2018)

Endogenous antimicrobial peptides (AMPs) are among the earliest molecular factors in the evolution of animal innate immunity. In this study, novel AMPs named nicomicins were identified in the small marine polychaeta Nicomache minor in the Maldanidae

Externí odkaz: https://doaj.org/article/e3a4b196616f4f168594bc7a74ab3c5c

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Akademický článek

Evaluating the Bioactivity of a Novel Broad-Spectrum Antimicrobial Peptide Brevinin-1GHa from the Frog Skin Secretion of Hylarana guentheri and Its Analogues

Autor: Qi Chen, Peng Cheng, Chengbang Ma, Xinping Xi, Lei Wang, Mei Zhou, Huimin Bian, Tianbao Chen

Publikováno v: Toxins, Vol 10, Iss 10, p 413 (2018)

Many antimicrobial peptides (AMPs) have been identified from the skin secretion of the frog Hylarana guentheri (H.guentheri), including Temporin, Brevinin-1, and Brevinin-2. In this study, an antimicrobial peptide named Brevinin-1GHa was identified f

Externí odkaz: https://doaj.org/article/0e56d1ad8d1a45e1927e791119c63d7a

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A novel antimicrobial peptide, Ranatuerin-2PLx (R2PLx), showing therapeutic potential in inhibiting proliferation of cancer cells

Autor: Chen, Xiaoling, Zhang, Luyao, Ma, Chengbang, Zhang, Yingqi, Xi, Xinping, Wang, Lei, Zhou, Mei, Burrows, James F., Chen, Tianbao

Publikováno v: Chen, X, Zhang, L, Ma, C, Zhang, Y, Xi, X, Wang, L, Zhou, M, Burrows, J F & Chen, T 2018, ' A novel antimicrobial peptide, Ranatuerin-2PLx (R2PLx), showing therapeutic potential in inhibiting proliferation of cancer cells ', Bioscience Reports, vol. 38, no. 6, BSR20180710 . https://doi.org/10.1042/BSR20180710

Antimicrobial peptides are a promising resource for developing novel antibiotic and even anticancer drugs. Here, a 28-mer polypeptide, R2PLx, was identified from lyophilised skin secretions. The chemically-synthetic replicates exhibited moderate and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2607::f5746dfdc7e44e6d641846e121be419a
https://pure.qub.ac.uk/en/publications/a-novel-antimicrobial-peptide-ranatuerin2plx-r2plx-showing-therapeutic-potential-in-inhibiting-proliferation-of-cancer-cells(79625d9b-e59b-48b4-a7d4-273a739c87e2).html

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A novel antimicrobial peptide, Ranatuerin-2PLx, showing therapeutic potential in inhibiting proliferation of cancer cells

Autor: Lei Wang, James F. Burrows, Luyao Zhang, Mei Zhou, Xiaoling Chen, Yingqi Zhang, Xinping Xi, Tianbao Chen, Chengbang Ma

Publikováno v: Bioscience Reports

Antimicrobial peptides are a promising resource for developing novel antibiotic and even anticancer drugs. Here, a 28-mer polypeptide, Ranatuerin-2PLx (R2PLx), was identified from lyophilised skin secretions. The chemically synthetic replicates exhib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7e7c4e7ffb956eb7ced04b55ad62b7
https://doi.org/10.1042/bsr20180710

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Novel Antimicrobial Peptides from the Arctic Polychaeta Nicomache minor Provide New Molecular Insight into Biological Role of the BRICHOS Domain

Autor: Ilia A. Bolosov, Alexander S. Paramonov, Mariana B Marggraf, S. V. Sychev, Pavel V. Panteleev, Zakhar O. Shenkarev, Tatiana V. Ovchinnikova, Andrey V Tsarev

Publikováno v: Marine Drugs
Volume 16
Issue 11
Marine Drugs, Vol 16, Iss 11, p 401 (2018)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06e240070b85fe0f285c3cea72a1699

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Evaluating the Bioactivity of a Novel Broad-Spectrum Antimicrobial Peptide Brevinin-1GHa from the Frog Skin Secretion of Hylarana guentheri and Its Analogues

Autor: Chengbang Ma, Huimin Bian, Peng Cheng, Mei Zhou, Tianbao Chen, Xinping Xi, Qi Chen, Lei Wang

Publikováno v: Toxins, Vol 10, Iss 10, p 413 (2018)
Chen, Q, Cheng, P, Ma, C, Xi, X, Wang, L, Zhou, M, Bian, H & Chen, T 2018, ' Evaluating the Bioactivity of a Novel Broad-Spectrum Antimicrobial Peptide Brevinin-1GHa from the Frog Skin Secretion of Hylarana guentheri and Its Analogues ', Toxins, vol. 10, no. 10, 413 . https://doi.org/10.3390/toxins10100413
Toxins
Volume 10
Issue 10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3140f0e00334bfe2fa4bc910cbe9f1b3
http://www.mdpi.com/2072-6651/10/10/413

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Predicting the Minimal Inhibitory Concentration for Antimicrobial Peptides with Rana-Box Domain

Autor: Tomislav Rončević, Damir Vukičević, Mara Kozic, Alessandro Tossi, Nikolinka Antcheva, Juraj Simunić, Davor Juretić

Publikováno v: Journal of Chemical Information and Modeling. 55:2275-2287

The global spreading of multidrug resistance has motivated the search for new antibiotic classes including different types of antimicrobial peptides (AMPs). Computational methods for predicting activity in terms of the minimal inhibitory concentratio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de5ace2f44ca728080193ce9b41536d4
https://doi.org/10.1021/acs.jcim.5b00161

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