Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Rana S, Moubarak"'
Autor:
Rana S. Moubarak, Lisa Koetz-Ploch, Gavriel Mullokandov, Avital Gaziel, Ana de Pablos-Aragoneses, Diana Argibay, Kevin Kleffman, Elena Sokolova, Marianne Berwick, Nancy E. Thomas, Iman Osman, Brian D. Brown, Eva Hernando
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Melanoma is a highly prevalent cancer with an increasing incidence worldwide and high metastatic potential. Brain metastasis is a major complication of the disease, as more than 50% of metastatic melanoma patients eventually develop intracranial dise
Externí odkaz:
https://doaj.org/article/ea266918aeb143fab6f07c8c6b79e495
Autor:
Qi Sun, Wendy Lee, Yasuaki Mohri, Makoto Takeo, Chae Ho Lim, Xiaowei Xu, Peggy Myung, Radhika P. Atit, M. Mark Taketo, Rana S. Moubarak, Markus Schober, Iman Osman, Denise L. Gay, Dieter Saur, Emi K. Nishimura, Mayumi Ito
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Currently, few mouse models exist to recapitulate human melanomagenesis. Here, the authors establish a c-Kit-CreER-driven model to target melanocyte stem cells (McSCs) and show that oncogenic McSCs give rise to epidermal melanoma that invade into the
Externí odkaz:
https://doaj.org/article/39566179028442d184f6030aa95f1bd5
Autor:
Elena Coccia, Isabel Calleja-Yagüe, Laura Planells-Ferrer, Blanca Sanuy, Belen Sanz, Joaquin López-Soriano, Rana S Moubarak, Francina Munell, Bruna Barneda-Zahonero, Joan X Comella, M Jose Pérez-García
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185327 (2017)
Fas Apoptosis Inhibitory Molecule (FAIM) is an evolutionarily highly conserved death receptor antagonist, widely expressed and known to participate in physiological and pathological processes. Two FAIM transcript variants have been characterized to d
Externí odkaz:
https://doaj.org/article/4ea246996fa14cdb8844fdf28fe83edf
Autor:
Arman Alberto Sorin, Shadaloey, Alcida, Karz, Rana S, Moubarak, Praveen, Agrawal, Grace, Levinson, Kevin, Kleffman, Orlando, Aristizabal, Iman, Osman, Youssef Z, Wadghiri, Eva, Hernando
Publikováno v:
Journal of Visualized Experiments.
Metastasis is a complex process, requiring cells to overcome barriers that are only incompletely modeled by in vitro assays. A systematic workflow was established using robust, reproducible in vivo models and standardized methods to identify novel pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06aea1bfc5ec197279ae96128a2e3f77
https://doi.org/10.3791/63186-v
https://doi.org/10.3791/63186-v
Autor:
Rana S. Moubarak, Ana de Pablos-Aragoneses, Vanessa Ortiz-Barahona, Yixiao Gong, Michael Gowen, Igor Dolgalev, Sorin A. A. Shadaloey, Diana Argibay, Alcida Karz, Richard Von Itter, Eleazar Carmelo Vega-Sáenz de Miera, Elena Sokolova, Farbod Darvishian, Aristotelis Tsirigos, Iman Osman, Eva Hernando
Publikováno v:
Science advances. 8(7)
The contribution of epigenetic dysregulation to metastasis remains understudied. Through a meta-analysis of gene expression datasets followed by a mini-screen, we identified Plant Homeodomain Finger protein 8 (PHF8), a histone demethylase of the Jumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585f6b77de4a5be05ba6f7a0bc7314ee
https://pubmed.ncbi.nlm.nih.gov/35179962
https://pubmed.ncbi.nlm.nih.gov/35179962
Autor:
Elena Sokolova, Sebastian Stefan, Iman Osman, Ana de Pablos-Aragoneses, Eleazar De Miera-Vega, Aristotelis Tsirigos, Yixiao Gong, Eva Hernando, Michael F. Gowen, Vanessa Ortiz-Barahona, Diana Argibay, Farbod Darvishian, Rana S. Moubarak, Igor Dolgalev, Richard Von Itter
Publikováno v:
Cancer Research. 80:B30-B30
The specific contribution of epigenetic dysregulation to the metastatic process remains understudied. Through a meta-analysis of gene expression datasets followed by a functional mini-screen, we identified PHF8, a histone demethylase of the Jumonji C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ae5f1d5ea69bc96710f16f3fcd3a87e
https://doi.org/10.1158/1538-7445.mel2019-b30
https://doi.org/10.1158/1538-7445.mel2019-b30
Autor:
Andreas Kloetgen, Alcida Karz, Karin C. Lilja, Maria Gabriela Berzoti-Coelho, Varshini Vasudevaraja, Beatriz Sánchez-Sendra, Jochen Imig, Iannis Aifantis, Douglas Hanniford, Rana S. Moubarak, Veronica Davalos, Tommaso Tabaglio, Alejandro Ulloa-Morales, Aristotelis Tsirigos, Iman Osman, Eva Hernando, Carlos Monteagudo, Ernesto Guccione, Pamela Wu
Publikováno v:
Cancer Research. 80:PR04-PR04
Metastasis is the primary cause of death of cancer patients. Dissecting mechanisms governing metastatic spread may uncover new biology and/or yield promising therapeutic insights. Here we investigated the role of circular RNAs (circRNAs), a class of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46d08fbd25b2c928e3551733c03db378
https://doi.org/10.1158/1538-7445.mel2019-pr04
https://doi.org/10.1158/1538-7445.mel2019-pr04
Autor:
Rana S. Moubarak, Andreas Kloetgen, Iannis Aifantis, Pamela Wu, Beatriz Sánchez-Sendra, Carlos Monteagudo, Maria Gabriela Berzoti-Coelho, Ernesto Guccione, Veronica Davalos, Tommaso Tabaglio, Varshini Vasudevaraja, Alejandro Ulloa-Morales, Iman Osman, Karin C. Lilja, Aristotelis Tsirigos, Eva Hernando, Douglas Hanniford, Alcida Karz, Diana Argibay, Jochen Imig
Publikováno v:
Cancer Cell
Summary Metastasis is the primary cause of death of cancer patients. Dissecting mechanisms governing metastatic spread may uncover important tumor biology and/or yield promising therapeutic insights. Here, we investigated the role of circular RNAs (c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9d30833ab06c08405bcb1d753c54cc
https://pubmed.ncbi.nlm.nih.gov/31935372
https://pubmed.ncbi.nlm.nih.gov/31935372
Autor:
Alun M. Davies, Raffaella Gozzelino, Carme Solé, Marta Pascual, Stephanie Reix, Rana S. Moubarak, Victor J. Yuste, Joan X. Comella, Rosa M. Soler, M. J. Perez-Garcia, Eduardo Soriano, Victoria Iglesias-Guimarais, Humberto Gutierrez, Marta Llovera, Miguel F. Segura
Publikováno v:
Repositorio Abierto de la UdL
Universitad de Lleida
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Universitad de Lleida
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
FLICE-inhibitory protein (FLIP) is an endogenous inhibitor of the signaling pathway triggered by the activation of death receptors. Here, we reveal a novel biological function for the long form of FLIP (FLIP-L) in neuronal differentiation, which can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50eb53b637ca42a7ab8c6f7e7f5b00d5
https://doi.org/10.1523/jneurosci.0537-10.2010
https://doi.org/10.1523/jneurosci.0537-10.2010
Autor:
Stephanie Reix, Bruna Barneda-Zahonero, Nuria Llecha-Cano, Joan X. Comella, Juan Carlos Arévalo, José M. Castellano, Rana S. Moubarak, Elena Coccia, Marisol Ruiz-Meana, Laura Planells-Ferrer, David Garcia-Dorado, Koen M.O. Galenkamp, Celia Fernandez-Sanz, Jorge Urresti
Death receptors are members of the tumor necrosis factor receptor superfamily involved in the extrinsic apoptotic pathway. Lifeguard (LFG) is a death receptor antagonist mainly expressed in the nervous system that specifically blocks Fas ligand (FasL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1314460ba241817a2aa2c893087391e6
https://europepmc.org/articles/PMC4714210/
https://europepmc.org/articles/PMC4714210/
