Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rana Montaser"'
Autor:
Rana Montaser, Grace E. Kenney, Neil L. Kelleher, Paul M. Thomas, Yun Ji Park, Amy C. Rosenzweig, Gerri M. Roberts
Publikováno v:
Biochemistry
Methanobactins (Mbns) are ribosomally produced, post-translationally modified peptidic natural products that bind copper with high affinity. Methanotrophic bacteria use Mbns to acquire copper needed for enzymatic methane oxidation. Despite the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a42d6bcbeb6ae1069947b8216cd0f0c
https://doi.org/10.1021/acs.biochem.1c00443
https://doi.org/10.1021/acs.biochem.1c00443
Publikováno v:
Nat Prod Rep
Covering: 2010 to 2021Organisms in nature have evolved into proficient synthetic chemists, utilizing specialized enzymatic machinery to biosynthesize an inspiring diversity of secondary metabolites. Often serving to boost competitive advantage for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1163fc12d4c2b861e767b67cd5aa12
https://europepmc.org/articles/PMC8691422/
https://europepmc.org/articles/PMC8691422/
Autor:
Neil L. Kelleher, Rana Montaser
Publikováno v:
ACS Chem Biol
Stravidins are peptide antibiotics produced by Streptomyces spp. Their antibacterial activity derives from an unusual amiclenomycin monomer, the warhead that inhibits biotin biosynthesis. Despite being discovered over five decades ago, stravidin bios
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d07019aaeb017518a69cea8b4988e87
https://doi.org/10.1021/acschembio.9b00890
https://doi.org/10.1021/acschembio.9b00890
Publikováno v:
Phytochemistry. 72:2068-2074
Pitipeptolides A ( 1 ) and B ( 2 ) are cyclic depsipeptides isolated from the marine cyanobacterium Lyngbya majuscula from Piti Bomb Holes, Guam. Additional analogues have now been isolated by revisiting larger collections of the same cyanobacterium.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ca206782b263579e811a640bab49f6
https://doi.org/10.1016/j.phytochem.2011.07.014
https://doi.org/10.1016/j.phytochem.2011.07.014
Publikováno v:
Planta Medica. 79
Novel bioactive lipids were identified from a Guamanian cyanobacterium, the Pseudomonas aeruginosa quorum sensing inhibitor pitinoic acid A (1) and the anti-inflammatory pitinoic acids B (2) and C. The structure of 2 was confirmed by synthesis, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200e6b3659adfc2e3f6644debcf3da3f
https://doi.org/10.1055/s-0033-1348539
https://doi.org/10.1055/s-0033-1348539
Lipids are utilized by diverse organisms, which suggests an evolutionarily conserved role of this class of compounds.[1] Indeed, lipidomics is emerging as a crucial field of research because of the key role of lipid biomolecules in a wide array of ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d58892a97434d64c42fca4cff424ad7
https://europepmc.org/articles/PMC3748600/
https://europepmc.org/articles/PMC3748600/
Publikováno v:
Planta Medica. 78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eb08d4fb13cbebc15b5f861b7f81bb0
https://doi.org/10.1055/s-0032-1320703
https://doi.org/10.1055/s-0032-1320703
Autor:
Hendrik Luesch, Rana Montaser
The largely unexplored marine world that presumably harbors the most biodiversity may be the vastest resource to discover novel ‘validated’ structures with novel modes of action that cover biologically relevant chemical space. Several challenges,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456da284a2e6a0fc220c58c9263de368
https://europepmc.org/articles/PMC3210699/
https://europepmc.org/articles/PMC3210699/
Publikováno v:
Journal of natural products. 74(4)
Malyngamide 3 (1) and cocosamides A (2) and B (3) were isolated from the lipophilic extract of a collection of Lyngbya majuscula from Cocos Lagoon, Guam. The planar structures of compounds 1-3 were determined by spectroscopic methods. The absolute co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbe7f7beb04be00ec9df584bb840a6d
https://pubmed.ncbi.nlm.nih.gov/21341718
https://pubmed.ncbi.nlm.nih.gov/21341718
Publikováno v:
Journal of natural products. 74(1)
An unusual cyclic depsipeptide, pitiprolamide (1), was isolated from the marine cyanobacterium Lyngbya majuscula collected at Piti Bomb Holes, Guam. The structure was deduced using NMR, MS, X-ray crystallography, and enantioselective HPLC-MS techniqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac3277d91a47013a1f58e8d64f2db10
https://pubmed.ncbi.nlm.nih.gov/21138309
https://pubmed.ncbi.nlm.nih.gov/21138309