Výsledky vyhledávání - "Rana M. Obaidat"

Evaluation and Characterization of Curcumin-β-Cyclodextrin and Cyclodextrin-Based Nanosponge Inclusion Complexation

Autor: Nizar A. Al-Shar’i, Hadeia Mashaqbeh, Rana M. Obaidat

Publikováno v: Polymers; Volume 13; Issue 23; Pages: 4073
Polymers
Polymers, Vol 13, Iss 4073, p 4073 (2021)

Cyclodextrin polymers and cyclodextrin-based nanosponges have been widely investigated for increasing drug bioavailability. This study examined curcumin’s complexation stability and solubilization with β-cyclodextrin and β-cyclodextrin-based nano

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c6187b2b5edbf82f642a7524180312

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Enhancement of dissolution of atorvastatin through preparation of polymeric solid dispersions using supercritical fluid technology

Autor: Bashar Al-Taani, Rana M. Obaidat, Walaa Malkawi

Publikováno v: Research in Pharmaceutical Sciences, Vol 15, Iss 2, Pp 123-136 (2020)
Research in Pharmaceutical Sciences

Background and purpose: This study aimed at preparation of solid dispersions in order to enhance dissolution of poorly water-soluble atorvastatin using supercritical CO2 technology. Atorvastatin has poor bioavailability of 12%, mainly due to poor wat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7246d8d535cca5524202a2b801864941
http://www.rpsjournal.net/article.asp?issn=1735-5362

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Development and Evaluation of Cocoa Butter Taste Masked Ibuprofen Using Supercritical Carbon Dioxide

Autor: Haneen Aleih, Mo'tasem M Alsmadi, Mohammad Alnaief, Bashar Al-Taani, Rana M. Obaidat, Hadeia Mashaqbeh

Publikováno v: AAPS PharmSciTech. 22(3)

Masking the unpleasant taste of the pharmaceutically active ingredients plays a critical role in patient acceptance, particularly for children. This work's primary objective was the preparation of taste-masked ibuprofen microparticles using cocoa but

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319a4f0ad1afdc139a0c5b188a2c0833
https://pubmed.ncbi.nlm.nih.gov/33719021

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Willingness and readiness to test for COVID‐19; A qualitative exploration of community pharmacists

Autor: Tareq L. Mukattash, Mohammad B. Nusair, Maher R. Khdour, Anan S. Jarab, Ibrahim L. Mukattash, Rana K Abu-Farha, Iman A. Basheti, Rana M. Obaidat

Publikováno v: International Journal of Clinical Practice

OBJECTIVES: The present study aimed to exploring community pharmacists' willingness and readiness to test for COVID-19 in Jordan. METHODS: Purposeful sampling was used to identify a list of 30 community pharmacies, which were approached to participat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5942a6e999e043a25cd4083eec3ac6b6

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Development, In Vitro Characterization, and In Vivo Toxicity Evaluation of Chitosan-Alginate Nanoporous Carriers Loaded with Cisplatin for Lung Cancer Treatment

Autor: Mohammad Alnaief, Nabil Hailat, Mo'tasem M Alsmadi, Borhan Albiss, Rana M. Obaidat

Publikováno v: AAPS PharmSciTech. 21(5)

Polysaccharide-based aerogels are promising drug carriers. Being nanoporous with a high specific surface area allows their use as a drug vehicle for various delivery routes. Intratracheal and intravenous administration of free cisplatin causes toxici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1455aef4fb61f7323ebbabf4f7d56efa
https://pubmed.ncbi.nlm.nih.gov/32661587

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Experimental and Computational Comparative Study of the Supercritical Fluid Technology (SFT) and Kneading Method in Preparing β-Cyclodextrin Complexes with Two Essential Oils (Linalool and Carvacrol)

Autor: Nizar A. Al-Shar’i, Rana M. Obaidat

Publikováno v: AAPS PharmSciTech. 19:1037-1047

Supercritical fluid technology (SFT) offers many advantages as a potential complexation method compared to the conventional kneading technique. Its applicability to processess in which solvents are not required is a significant benefit. The main aim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb7bb5ccd9119b609a619e82d3d278b
https://doi.org/10.1208/s12249-017-0915-x

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Significant solubility of carbon dioxide in Soluplus®facilitates impregnation of ibuprofen using supercritical fluid technology

Autor: Rana M. Obaidat, P. Jaeger, Mohammed Alnaief

Publikováno v: Pharmaceutical Development and Technology. 23:697-705

Treatment of Soluplus® with supercritical carbon dioxide allows promising applications in preparing dispersions of amorphous solids. Several characterization techniques were employed to reveal this...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0477cb297b7c4209e463f2dcda14d45
https://doi.org/10.1080/10837450.2017.1315135

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A Comparative Solubility Enhancement Study of Cefixime Trihydrate Using Different Dispersion Techniques

Autor: Rana M. Obaidat, Rand Ghanma, Mai Khanfar

Publikováno v: AAPS PharmSciTech. 20

This study aimed to investigate the effect of different polymers (polyethylene glycol 4000 and 6000 and Soluplus®) on the enhancement of solubility, dissolution, and stability of cefixime trihydrate as a selected class II model drug. Different solid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cbf445d8218f2013ee081e69520f097
https://doi.org/10.1208/s12249-019-1395-y

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