Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Rana Al–Sadi"'
Autor:
Mohammad Haque, Lauren Kaminsky, Raz Abdulqadir, Jessica Engers, Evgeny Kovtunov, Manmeet Rawat, Rana Al-Sadi, Thomas Y. Ma
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundDefective intestinal epithelial tight junction (TJ), characterized by an increase in intestinal TJ permeability, has been shown to play a critical role in the pathogenesis of inflammatory bowel disease (IBD). Tumor necrosis factor-α (TNF-
Externí odkaz:
https://doaj.org/article/3d6dadc85d734c34991bd87666b04db4
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/46f21757596147fda608b89a537d191a
Autor:
Arun K. Bhunia, Rana Al-Sadi
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/d217562cbf3848f4a2991d2ad0c35099
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The intestinal epithelial tight junction (TJ) barrier controls the paracellular permeation of contents from the intestinal lumen into the intestinal tissue and systemic circulation. A defective intestinal TJ barrier has been implicated as an importan
Externí odkaz:
https://doaj.org/article/50880881135a4f49be1e7cbefd33c25f
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249544 (2021)
BackgroundMatrix Metalloproteinase-9 (MMP-9) has been shown to play a key role in mediating inflammation and tissue damage in inflammatory bowel disease (IBD). In patients with IBD, the intestinal tight junction (TJ) barrier is compromised as charact
Externí odkaz:
https://doaj.org/article/a99bf2b54bf045f58f910341a4a306e5
Autor:
Rana Al-Sadi, Viszwapriya Dharmaprakash, Prashant Nighot, Shuhong Guo, Meghali Nighot, Toan Do, Thomas Y. Ma
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8070 (2021)
Defective intestinal tight junction (TJ) barrier is a hallmark in the pathogenesis of inflammatory bowel disease (IBD). To date, there are no effective therapies that specifically target the intestinal TJ barrier. Among the various probiotic bacteria
Externí odkaz:
https://doaj.org/article/33a7fb3b09174925bf41e44493371cdf
Autor:
Rana Al-Sadi, Dongmei Ye, Michel Boivin, Shuhong Guo, Mariam Hashimi, Lisa Ereifej, Thomas Y Ma
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e85345 (2014)
Defective intestinal epithelial tight junction (TJ) barrier has been shown to be a pathogenic factor in the development of intestinal inflammation. Interleukin-6 (IL-6) is a pleiotropic, pro-inflammatory cytokine which plays an important role in prom
Externí odkaz:
https://doaj.org/article/9450d683aaad49ce99772a26468e984f
Publikováno v:
Physiology. 38
Background: Bifidobacteria are commonly utilized probiotics that have been shown to protect against intestinal inflammation in part by enhancing the intestinal epithelial tight junction (TJ) barrier function. It has been recently shown that Bifidobac
Publikováno v:
Physiology. 38
Background: Bifidobacterium bifidum (BB) is one of the most common probiotic bacteria strains that have been shown to have protective effects against intestinal inflammation, primarily by enhancing the intestinal epithelial tight junction (TJ) barrie
Autor:
Meghali Nighot, Manmeet Rawat, Rana Al-Sadi, Thomas Y. Ma, Mohammad Rashedul Haque, Prashant Nighot
Publikováno v:
Am J Pathol
Defective intestinal tight junction (TJ) barrier is an important pathogenic factor of inflammatory bowel disease. To date, no effective therapies that specifically target the intestinal TJ barrier are available. The purpose of this study was to ident