Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Rana Abdel-Samad"'
Autor:
Nadine Darwiche, Hiba El Hajj, Claudio Pisano, Angelo Mancinelli, Maguy Hamie, Rita Hleihel, Rana Abdel-Samad, Nadim Tawil, Patrick Aouad, Berthe Hayar, Walid Saad, Leeanna El-Houjeiri
Acute myeloid leukemia (AML) is one of the most frequent types of blood malignancies. It is a complex disorder of undifferentiated hematopoietic progenitor cells. The majority of patients generally respond to intensive therapy. Nevertheless, relapse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ad82201abdefdaa82770540556c3844
https://doi.org/10.1158/1535-7163.c.6538707.v1
https://doi.org/10.1158/1535-7163.c.6538707.v1
Autor:
Nadine Darwiche, Hiba El Hajj, Claudio Pisano, Angelo Mancinelli, Maguy Hamie, Rita Hleihel, Rana Abdel-Samad, Nadim Tawil, Patrick Aouad, Berthe Hayar, Walid Saad, Leeanna El-Houjeiri
Supplementary Figure S1. Effect of ST1926 on the viability of AML cells; Supplementary Figure S2. Effect of ST1926 on the viability of normal human stem cells; Supplementary Figure S3. Representative histogram analysis of the effects of ST1926 on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d931eb7dfacacddb2b41b5f7499373
https://doi.org/10.1158/1535-7163.22507488
https://doi.org/10.1158/1535-7163.22507488
Autor:
Hala El Ouweini, Wassim Abou-Kheir, Alissar Monzer, Nadine Darwiche, Hala Gali-Muhtasib, Farah Ballout, Rana Abdel-Samad, Miran A. Jaffa, Maamoun Fatfat
Publikováno v:
Oncotarget
The high recurrence rates of colorectal cancer have been associated with a small population of cancer stem cells (CSCs) that are resistant to the standard chemotherapeutic drug, 5-fluorouracil (5FU). Thymoquinone (TQ) has shown promising antitumor pr
Publikováno v:
Anti-cancer drugs. 30(7)
Colorectal cancer (CRC) remains a leading cause of cancer-related morbidity and mortality worldwide. Although targeted therapy in combination with chemotherapy in CRC prolongs the overall survival of patients with metastatic disease, acquired resista
Autor:
Katia Cheaito, Hisham F. Bahmad, Wassim Abou-Kheir, Berthe Hayar, Nadine Darwiche, Claudio Pisano, Hiba Msheik, Yen-Nien Liu, Alissar Monzer, Houda Samman, Rana Abdel-Samad, Ola Hadadeh
Publikováno v:
Molecular Carcinogenesis.
Retinoids are vitamin A derivatives that regulate crucial biological processes such as cellular proliferation, apoptosis, and differentiation. The use of natural retinoids in cancer therapy is limited due to their toxicity and the acquired resistance
Autor:
Maamoun Fatfat, Nadine Darwiche, Hala-Gali Muhtasib, Regine Schneider-Stock, Wassim Abou-Kheir, Rana Abdel-Samad, Farah Ballout
Publikováno v:
Cancer Research. 78:170-170
Introduction: 5-fluorouracil (5-Fu) remains the standard chemotherapy for metastatic colorectal cancer (CRC), but drug resistance and unpredictable cardiotoxicity limit its effectiveness. The high recurrence rates and the common resistance are though
Autor:
Nadine Darwiche, Louna Karam, Rana Abdel-Samad, Claudio Pisano, Frank Neipel, Iman Halloum, Bilal Houshaymi, Raghida Abou Merhi, Mariam Jaafar
Publikováno v:
Oncology reports. 39(2)
Primary effusion lymphoma (PEL) is a rare B-cell neoplasm, associated with Kaposi sarcoma-associated herpes virus/human herpes virus-8 (KSHV/HHV-8), arising as malignant effusions in body cavities. PEL cells do not harbor conventional genetic cancer
Autor:
Sabreen F. Fostok, Patrick Aouad, Claudio Pisano, Leeanna El-Houjeiri, Nadine Darwiche, Melody Saikali, Rabih S. Talhouk, Rana Abdel-Samad
Publikováno v:
Anti-cancer drugs. 28(7)
Despite recent advances in chemotherapy, aggressive and metastatic breast cancers remain refractory to targeted therapy and the development of novel drugs is urgently needed. Retinoids are crucial regulators of cellular proliferation, differentiation
Autor:
William W. Hall, Akram Ghantous, Rihab Nasr, Ghassan Dbaibo, Ali Bazarbachi, Hideki Hasegawa, Ghazi Zaatari, Rana Abdel-Samad, Mark Jabbour, Botheina Ghandour, Claudio Pisano, Bariaa Khalil, Ansam Sinjab, Sharif Shahine, Nadine Darwiche, Hiba El Hajj
Publikováno v:
Blood. 124:2072-2080
Adult T-cell leukemia/lymphoma (ATL) is an aggressive neoplasm caused by human T-cell leukemia virus type 1 (HTLV-1). The HTLV-1 oncoprotein Tax plays an important role in ATL pathogenesis. ATL carries a poor prognosis due to chemotherapy resistance,
Autor:
Maguy Hamie, Angelo Mancinelli, Nadine Darwiche, Patrick Aouad, Claudio Pisano, Walid Saad, Berthe Hayar, Rana Abdel-Samad, Nadim Tawil, Hiba El Hajj, Rita Hleihel, Leeanna El-Houjeiri
Publikováno v:
Molecular cancer therapeutics. 16(10)
Acute myeloid leukemia (AML) is one of the most frequent types of blood malignancies. It is a complex disorder of undifferentiated hematopoietic progenitor cells. The majority of patients generally respond to intensive therapy. Nevertheless, relapse