New potential antiproliferative monophosphoester 2-aminoethyl dihydrogen phosphate in K-562 and K-562 MDR+ leukemia cells

Autor: TO. Conceição, LGS. Cabral, MG. Laveli-Silva, JC. Pacheco, MG. Alves, DC. Rabelo, RAN. Laiso, DA. Maria

Publikováno v: Biomedicine & Pharmacotherapy, Vol 142, Iss , Pp 112054- (2021)

The main obstacle in the treatment of cancer patients has been resistance to multiple drugs, leading to the need to develop molecules with a higher specificity target. The liposomal formulation DODAC/2-AEH2P has antitumor potential, inducing apoptosi

Externí odkaz: https://doaj.org/article/fcead2b78a054295a3cde6e23ac00360

New potential antiproliferative monophosphoester 2-aminoethyl dihydrogen phosphate in K-562 and K-562 MDR

Autor: T O, Conceição, Lgs, Cabral, M G, Laveli-Silva, J C, Pacheco, M G, Alves, D C, Rabelo, Ran, Laiso, D A, Maria

Publikováno v: Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 142

The main obstacle in the treatment of cancer patients has been resistance to multiple drugs, leading to the need to develop molecules with a higher specificity target. The liposomal formulation DODAC/2-AEH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5535956989d129acec2e8e2985044331
https://pubmed.ncbi.nlm.nih.gov/34463267

2-Aminoethyl Dihydrogen Phosphate (2-AEH2P) Associated with Cell Metabolism-Modulating Drugs Presents a Synergistic and Pro-Apoptotic Effect in an In Vitro Model of the Ascitic Ehrlich Tumor.

Autor: Alves MG; Development and Innovation Laboratory, Butantan Institute, São Paulo 05359-900, Brazil.; Graduate Program in Medical Sciences, College of Medicine, University of São Paulo, São Paulo 05508-220, Brazil., Cabral LGS; Development and Innovation Laboratory, Butantan Institute, São Paulo 05359-900, Brazil.; Graduate Program in Medical Sciences, College of Medicine, University of São Paulo, São Paulo 05508-220, Brazil., Totti PGF; Graduate Program in Structural and Functional Interactions in Rehabilitation, Postgraduate Department, University of Marília (UNIMAR), Marília 17525-902, Brazil., Azarias FR; Development and Innovation Laboratory, Butantan Institute, São Paulo 05359-900, Brazil., Pomini KT; Graduate Program in Structural and Functional Interactions in Rehabilitation, Postgraduate Department, University of Marília (UNIMAR), Marília 17525-902, Brazil., Rici REG; Graduate Program in Structural and Functional Interactions in Rehabilitation, Postgraduate Department, University of Marília (UNIMAR), Marília 17525-902, Brazil.; Graduate Program in Anatomy of Domestic and Wild Animals, College of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo 05508-220, Brazil., Laiso RAN; Development and Innovation Laboratory, Butantan Institute, São Paulo 05359-900, Brazil., Maria DA; Development and Innovation Laboratory, Butantan Institute, São Paulo 05359-900, Brazil.; Graduate Program in Medical Sciences, College of Medicine, University of São Paulo, São Paulo 05508-220, Brazil.

Publikováno v: Biomedicines [Biomedicines] 2024 Jan 04; Vol. 12 (1). Date of Electronic Publication: 2024 Jan 04.