Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ran Hee Choi"'
Autor:
Ran-hee Choi
Publikováno v:
The Journal of Chinese Language and Literature. 130:71-94
Publikováno v:
Biochem Biophys Res Commun
Brown adipose tissue (BAT) and stimulating adaptive thermogenesis have been implicated as anti-obese and anti-diabetic tissues due to their ability to dissipate energy as heat by the expression of UCP1. We have recently demonstrated that TRB3 impairs
Autor:
JONATHAN W. SNYDER, SARAH K. MONTGOMERY, NICOLAI M. DOLIBA, JEFFREY ROMAN, YUZHEN TIAN, PRISCILA Y. SATO, WILLIAM L. HOLLAND, RAN HEE CHOI
Publikováno v:
Diabetes. 71
Insulin deficiency is central to diabetes and diabetes-related cardiac dysfunction. GPCRs are known modulators of insulin secretion and a main pharmacological target in various tissues, including the heart. GPCR kinase 2 (GRK2) phosphorylates activat
Publikováno v:
Nat Rev Cardiol
Increases in calorie consumption and sedentary lifestyles are fuelling a global pandemic of cardiometabolic diseases, including coronary artery disease, diabetes mellitus, cardiomyopathy and heart failure. These lifestyle factors, when combined with
Publikováno v:
Biochem Biophys Res Commun
AMP-activated protein kinase (AMPK) is a member of Ser/Thr kinases that has been shown to regulate energy balance. Although recent studies have demonstrated the function of AMPK in adipose tissue using different fat-specific AMPK knockout mouse model
Autor:
Ho-Jin Koh, Ran Hee Choi, João G Silvestre, Anselmo Sigari Moriscot, James A. Carson, Abigail McConahay
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(4)
Tribbles 3 (TRB3) is a pseudokinase that has been found in multiple tissues in response to various stress stimuli, such as nutrient deprivation and endoplasmic reticulum (ER) stress. We recently found that TRB3 has the potential to regulate skeletal
Publikováno v:
Diabetes. 67
AMP-activated protein kinase (AMPK) is a member of Ser/Thr kinases that has been shown to regulate energy balance. Although recent studies have demonstrated the function of AMPK in adipose tissue using different fat-specific AMPK knockout mouse model
Publikováno v:
The FASEB Journal. 32
Autor:
Laurie J. Goodyear, Ha-Won Jeong, Abigail McConahay, Jamie L. McClellan, Ran Hee Choi, Michael F. Hirshman, Justin P. Hardee, James A. Carson, Ho-Jin Koh
Publikováno v:
Biochemical and biophysical research communications. 493(3)
Skeletal muscle atrophy is associated with a disruption in protein turnover involving increased protein degradation and suppressed protein synthesis. Although it has been well studied that the IGF-1/PI3K/Akt pathway plays an essential role in the reg
Autor:
Gerardo G. Piroli, Jamie L. McClellan, Ran Hee Choi, Yu-Hua Tseng, Ho-Jin Koh, Norma Frizzell, Laurie J. Goodyear, Ha-Won Jeong
Publikováno v:
Biochemical and biophysical research communications. 470(4)
Recent studies have demonstrated that adult humans have substantial amounts of functioning brown adipose tissue (BAT). Since BAT has been implicated as an anti-obese and anti-diabetic tissue, it is important to understand the signaling molecules that