Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Ramzi J. Khairallah"'
Autor:
Justin G. Boyer, Jiuzhou Huo, Sarah Han, Julian R. Havens, Vikram Prasad, Brian L. Lin, David A. Kass, Taejeong Song, Sakthivel Sadayappan, Ramzi J. Khairallah, Christopher W. Ward, Jeffery D. Molkentin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Boyer et al. created genetic mouse models of muscular dystrophy in which satellite cells were selectively depleted. The depletion of satellite cells at select times was protective. Myofibers no longer had plasma membrane instability leading to tissue
Externí odkaz:
https://doaj.org/article/05d4e5eb19ab42dd9227ed224828f09d
Autor:
Matthieu Ruiz, Maya Khairallah, Dharmendra Dingar, George Vaniotis, Ramzi J. Khairallah, Benjamin Lauzier, Simon Thibault, Joëlle Trépanier, Yanfen Shi, Annie Douillette, Bahira Hussein, Sherin Ali Nawaito, Pramod Sahadevan, Albert Nguyen, Fatiha Sahmi, Marc‐Antoine Gillis, Martin G. Sirois, Matthias Gaestel, William C. Stanley, Céline Fiset, Jean‐Claude Tardif, Bruce G. Allen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 4 (2021)
Background Mitogen‐activated protein kinase–activated protein kinase‐2 (MK2) is a protein serine/threonine kinase activated by p38α/β. Herein, we examine the cardiac phenotype of pan MK2‐null (MK2−/−) mice. Methods and Results Survival
Externí odkaz:
https://doaj.org/article/f621d6d646c848bc8cfc1f57645591d9
Autor:
Sajedah M. Hindi, Michael J. Petrany, Elena Greenfeld, Leah C. Focke, Alyssa A.W. Cramer, Michael A. Whitt, Ramzi J. Khairallah, Christopher W. Ward, Jeffrey S. Chamberlain, Benjamin Podbilewicz, Vikram Prasad, Douglas P. Millay
Publikováno v:
Cell. 186:2062-2077.e17
Autor:
Ramzi J Khairallah, Karen M O'Shea, Christopher W Ward, Dustie N Butteiger, Ratna Mukherjea, Elaine S Krul
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189246 (2017)
Athletes as well as elderly or hospitalized patients use dietary protein supplementation to maintain or grow skeletal muscle. It is recognized that high quality protein is needed for muscle accretion, and can be obtained from both animal and plant-ba
Externí odkaz:
https://doaj.org/article/4e22745d56a44cb5bb5598bdd524d41a
Autor:
Justin G. Boyer, Jiuzhou Huo, Sarah Han, Julian R. Havens, Vikram Prasad, Brian L. Lin, David A. Kass, Taejeong Song, Sakthivel Sadayappan, Ramzi J. Khairallah, Christopher W. Ward, Jeffery D. Molkentin
Publikováno v:
Nature communications. 13(1)
Skeletal muscle can repair and regenerate due to resident stem cells known as satellite cells. The muscular dystrophies are progressive muscle wasting diseases underscored by chronic muscle damage that is continually repaired by satellite cell-driven
Autor:
Karen S. Chen, Kelly Howell, Shaun M. Cote, Karen M. O'Shea, Joseph P. Stains, Sergey Paushkin, Adriana Donovan, Erin Renae Treece, Ramzi J. Khairallah, Alan Buckler, Long Kimberly, Micah T. Webster
Publikováno v:
Human Molecular Genetics
Spinal muscular atrophy (SMA) is a neuromuscular disease characterized by loss of α-motor neurons, leading to profound skeletal muscle atrophy. Patients also suffer from decreased bone mineral density and increased fracture risk. The majority of tre
Autor:
Manasa P Srikanth, Jenna Leser, Marcus Hughes, Joseph P. Stains, Katrina M. Williams, Ricardo A. Feldman, Nicole R. Gould, Humberto C. Joca, Olivia M. Torre, Ramzi J. Khairallah, Christopher W. Ward, James S. Lyons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9506f8e74a22f53e36b3fe8661c46302
https://doi.org/10.7554/elife.64393.sa2
https://doi.org/10.7554/elife.64393.sa2
Autor:
George Vaniotis, Maya Khairallah, Céline Fiset, Jean-Claude Tardif, William C. Stanley, Bahira Hussein, Joëlle Trépanier, Yanfen Shi, Bruce G. Allen, Albert Nguyen, Sherin Ali Nawaito, Benjamin Lauzier, Simon Thibault, Matthias Gaestel, Matthieu Ruiz, Marc-Antoine Gillis, Ramzi J. Khairallah, Fatiha Sahmi, Dharmendra Dingar, Martin G. Sirois, Annie Douillette, Pramod Sahadevan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 4 (2021)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Mitogen‐activated protein kinase–activated protein kinase‐2 (MK2) is a protein serine/threonine kinase activated by p38α/β. Herein, we examine the cardiac phenotype of pan MK2‐null (MK2 −/− ) mice. Methods and Results Surviva
Autor:
Ramzi J. Khairallah, Christopher W. Ward, Marcus Hughes, James S. Lyons, Jenna Leser, Humberto C. Joca, Manasa P Srikanth, Katrina M. Williams, Nicole R. Gould, Olivia M. Torre, Joseph P. Stains, Ricardo A. Feldman
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
The down regulation of sclerostin mediates bone formation in response to mechanical cues and parathyroid hormone (PTH). To date, the regulation of sclerostin has been attributed exclusively to the transcriptional downregulation that occurs hours afte
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 15
International Journal of Molecular Sciences, Vol 21, Iss 5504, p 5504 (2020)
Volume 21
Issue 15
International Journal of Molecular Sciences, Vol 21, Iss 5504, p 5504 (2020)
The flight muscle of Manduca sexta (DLM1) is an emerging model system for biophysical studies of muscle contraction. Unlike the well-studied indirect flight muscle of Lethocerus and Drosophila, the DLM1 of Manduca is a synchronous muscle, as are the