Zobrazeno 1 - 10
of 226
pro vyhledávání: '"Ramzi A, Ajjan"'
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 12, Iss 2 (2024)
Introduction Identify non-glycemic factors affecting the relationship between fasting plasma glucose (FPG) and glycated hemoglobin (HbA1c), in order to refine diabetes diagnostic criteria.Research design and methods Relationship between FPG–HbA1c w
Externí odkaz:
https://doaj.org/article/f2168046753c4def92c8a383a5bc16bc
Autor:
Stephen J. Hierons, Kazim Abbas, Amélie I. S. Sobczak, Michela Cerone, Terry K. Smith, Ramzi A. Ajjan, Alan J. Stewart
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Obesity is a complex disease that increases an individual’s risk of developing other diseases and health-related problems. A common feature is dyslipidemia characterized by increased levels of plasma lipids, which include non-esterified fa
Externí odkaz:
https://doaj.org/article/f5d49af16dc54d819bbb745b644ba1f8
Autor:
William A. E. Parker, Rebecca Sagar, Zeyad Kurdee, Fladia Hawkins, Khalid M. Naseem, Peter J. Grant, Robert F. Storey, Ramzi A. Ajjan
Publikováno v:
Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-14 (2021)
Abstract Background The enhanced thrombotic milieu in diabetes contributes to increased risk of vascular events. Aspirin, a key antiplatelet agent, has inconsistent effects on outcomes in diabetes and the best dosing regimen remains unclear. This wor
Externí odkaz:
https://doaj.org/article/aa1afab07e974126b45b3d906041108f
Autor:
Basmah Alsayejh, Noppadol Kietsiriroje, Mansour Almutairi, Katie Simmons, Nikoletta Pechlivani, Sreenivasan Ponnambalam, Ramzi A. Ajjan
Publikováno v:
TH Open, Vol 06, Iss 04, Pp e396-e407 (2022)
Abstract The vascular obstructive thrombus is composed of a mesh of fibrin fibers with blood cells trapped in these networks. Enhanced fibrin clot formation and/or suppression of fibrinolysis are associated with an increased risk of vascular occlusi
Externí odkaz:
https://doaj.org/article/c4ed8a57ea634e09829e465ce1a35a1e
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 20 (2022)
Thromboinflammation has become a topic of key interest in cardiovascular disease and the prevention of diabetes complications because of the interplay between thrombosis and inflammation in diabetes. Specifically, the significant risk of vascular thr
Externí odkaz:
https://doaj.org/article/90b662e53dd74622aa10bc57df47fb4f
Autor:
Sam M. Pearson, Beverley Whittam, Kavita Kulavarasalingam, Amelia Mitchell-Gears, Cathyrn James, Ramzi A. Ajjan
Publikováno v:
Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-11 (2021)
Abstract Background Mortality in individuals with diabetes with severe hypoglycemia requiring ambulance services intervention is high and it is unclear whether this is modifiable. Our aim was to characterise this high-risk group and assess the impact
Externí odkaz:
https://doaj.org/article/1d4b2e228faf4f92bf64060104e3ac34
Autor:
Lauren L. O’Mahoney, Gareth Dunseath, Rachel Churm, Mel Holmes, Christine Boesch, Antonios Stavropoulos-Kalinoglou, Ramzi A. Ajjan, Karen M. Birch, Nicolas M. Orsi, Georgia Mappa, Oliver J. Price, Matthew D. Campbell
Publikováno v:
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-10 (2020)
Abstract Background The role of omega-3 polyunsaturated fatty acids (n-3PUFA), and the potential impact of n-3PUFA supplementation, in the treatment and management of type 1 diabetes (T1D) remains unclear and controversial. Therefore, this study aime
Externí odkaz:
https://doaj.org/article/841718ca3b6540cfa2428c513944997e
Autor:
William A. E. Parker, Christian Schulte, Temo Barwari, Fladia Phoenix, Sam M. Pearson, Manuel Mayr, Peter J. Grant, Robert F. Storey, Ramzi A. Ajjan
Publikováno v:
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-13 (2020)
Abstract Background Despite increased atherothrombotic risk in type 2 diabetes mellitus, (T2DM) the best preventative antithrombotic strategy remains undetermined. We defined the effects of three antiplatelet agents on functional readout and biomarke
Externí odkaz:
https://doaj.org/article/9f1c77799f1f4dd284bc759ec7a7f192
Autor:
Helen R McPherson, Cedric Duval, Stephen R Baker, Matthew S Hindle, Lih T Cheah, Nathan L Asquith, Marco M Domingues, Victoria C Ridger, Simon DA Connell, Khalid M Naseem, Helen Philippou, Ramzi A Ajjan, Robert AS Ariëns
Publikováno v:
eLife, Vol 10 (2021)
Fibrinogen is essential for blood coagulation. The C-terminus of the fibrinogen α-chain (αC-region) is composed of an αC-domain and αC-connector. Two recombinant fibrinogen variants (α390 and α220) were produced to investigate the role of subre
Externí odkaz:
https://doaj.org/article/c1db5394e1864b85a4927dd251608dff
Publikováno v:
eLife, Vol 10 (2021)
Laboratory HbA1c does not always predict diabetes complications and our aim was to establish a glycaemic measure that better reflects intracellular glucose exposure in organs susceptible to complications. Six months of continuous glucose monitoring d
Externí odkaz:
https://doaj.org/article/61914c6109ee47a8a9e12467d7fdc9e8