Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ramzi, Temanni"'
Autor:
Juan L. Rodriguez-Flores, Radja Messai-Badji, Amal Robay, Ramzi Temanni, Najeeb Syed, Monika Markovic, Eiman Al-khayat, Fatima Qafoud, Zafar Nawaz, Ramin Badii, Yasser Al-Sarraj, Hamdi Mbarek, Wadha Al-Muftah, Muhammad Alvi, Mahboubeh R. Rostami, Juan Carlos Martinez Cruzado, Jason G. Mezey, Alya Al Shakaki, Joel A. Malek, Matthew B. Greenblatt, Khalid A. Fakhro, Khaled Machaca, Ajayeb Al-Nabet, Nahla Afifi, Andrew Brooks, Said I. Ismail, Asmaa Althani, Ronald G. Crystal
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-21 (2022)
Abstract Risk genes for Mendelian (single-gene) disorders (SGDs) are consistent across populations, but pathogenic risk variants that cause SGDs are typically population-private. The goal was to develop “QChip1,” an inexpensive genotyping microar
Externí odkaz:
https://doaj.org/article/37726560b48d41ea9a863392829c265f
Genetic variations influence brain changes in patients with attention-deficit hyperactivity disorder
Autor:
Santosh K. Yadav, Ajaz A. Bhat, Sheema Hashem, Sabah Nisar, Madeeha Kamal, Najeeb Syed, Mohamed-Ramzi Temanni, Rakesh K. Gupta, Saddat Kamran, Muhammad Waqar Azeem, Amit K. Srivastava, Puneet Bagga, Sanjeev Chawla, Ravinder Reddy, Michael P. Frenneaux, Khalid Fakhro, Mohammad Haris
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-24 (2021)
Abstract Attention-deficit hyperactivity disorder (ADHD) is a neurological and neurodevelopmental childhood-onset disorder characterized by a persistent pattern of inattentiveness, impulsiveness, restlessness, and hyperactivity. These symptoms may co
Externí odkaz:
https://doaj.org/article/9a95aa908105461da6827b335e5c5f24
Autor:
Muna Al Hashmi, Konduru S. Sastry, Lee Silcock, Lotfi Chouchane, Valentina Mattei, Nicola James, Rebecca Mathew, Davide Bedognetti, Valeria De Giorgi, Daniela Murtas, Wei Liu, Aouatef Chouchane, Ramzi Temanni, Barbara Seliger, Ena Wang, Francesco M. Marincola, Sara Tomei
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-9 (2020)
Abstract Background Most mutations in melanoma affect one critical amino acid on BRAF gene, resulting in the V600E substitution. Patient management is often based on the use of specific inhibitors targeting this mutation. Methods DNA and RNA mutation
Externí odkaz:
https://doaj.org/article/76b0fbde5d5541b99ead96b5816d2060
Autor:
Lee Silcock, Hakeem Almabrazi, Younes Mokrab, Puthen Jithesh, Muna Al-Hashmi, Nicola James, Rebecca Mathew, Valentina Mattei, Davide Bedognetti, Francesca Lessi, Ramzi Temanni, Barbara Seliger, Rashid Al-Ali, Francesco M. Marincola, Ena Wang, Sara Tomei
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-7 (2019)
Abstract Background Monoallelic expression (MAE) is a frequent genomic phenomenon in normal tissues, however its role in cancer is yet to be fully understood. MAE is defined as the expression of a gene that is restricted to one allele in the presence
Externí odkaz:
https://doaj.org/article/fd11d94296a64e7f83edce668d7c986b
Autor:
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane
Publikováno v:
Hepatology, 77(2), 501-511. Wiley
Background and Aims: Porto-sinusoidal vascular disorder (PSVD) is a group of liver vascular diseases featuring lesions encompassing the portal venules and sinusoids unaccompanied by cirrhosis, irrespective of the presence/absence of portal hypertensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8416a3e5c4888bf7ef234b5afe101e
https://research.rug.nl/en/publications/d09352ba-1531-43cd-a1a2-2ff122dd7dff
https://research.rug.nl/en/publications/d09352ba-1531-43cd-a1a2-2ff122dd7dff
Autor:
Sahar Isa Da’as, Waseem Hasan, Rola Salem, Nadine Younes, Doua Abdelrahman, Iman A. Mohamed, Arwa Aldaalis, Ramzi Temanni, Lisa Sara Mathew, Stephan Lorenz, Magdi Yacoub, Michail Nomikos, Gheyath K. Nasrallah, Khalid A. Fakhro
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 8840
Variants in cardiac myosin-binding protein C (cMyBP-C) are the leading cause of inherited hypertrophic cardiomyopathy (HCM), demonstrating the key role that cMyBP-C plays in the heart’s contractile machinery. To investigate the c-MYBPC3 HCM-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f8469169f445c5aac84e954b5e6548
Autor:
Yuan Li, Sheena Shah-Simpson, Kwame Okrah, A Trey Belew, Jungmin Choi, Kacey L Caradonna, Prasad Padmanabhan, David M Ndegwa, M Ramzi Temanni, Héctor Corrada Bravo, Najib M El-Sayed, Barbara A Burleigh
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005511 (2016)
Intracellular colonization and persistent infection by the kinetoplastid protozoan parasite, Trypanosoma cruzi, underlie the pathogenesis of human Chagas disease. To obtain global insights into the T. cruzi infective process, transcriptome dynamics w
Externí odkaz:
https://doaj.org/article/64b098f26aac404f98716b062479c8bd
Autor:
Shahrad Taheri, Fadhil Abubaker, Bushra Memon, Ihab Younis, Yasmin Abu Aqel, Mohammed Bashir, Manjula Nandakumar, Ahmed Elsayed, Gowher Ali, Ramzi Temanni, Essam M. Abdelalim
Publikováno v:
Stem Cells and Development
Psoriasis is characterized by hyperproliferation and defective differentiation of keratinocytes (KCs). Patients with psoriasis are at a high risk of developing diabetes and cardiovascular diseases. The debate on the genetic origin of psoriasis pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6ded42654bd0ceb310b320266bb5b4
https://doi.org/10.1089/scd.2019.0150
https://doi.org/10.1089/scd.2019.0150
Autor:
Mohamad Saad, Younes Mokrab, Najeeb Halabi, Jingxuan Shan, Rozaimi Razali, Khalid Kunji, Najeeb Syed, Ramzi Temanni, Murugan Subramanian, Michele Ceccarelli, Arash Rafii Tabrizi, Davide Bedognetti, Lotfi Chouchane, Said I Ismail, Wadha Al-Muftah, Radja Badji, Hamdi Mbarek, Dima Darwish, Tasnim Fadl, Heba Yasin, Maryem Ennaifar, Rania Abdellatif, Fatima Alkuwari, Muhammad Alvi, Yasser Al-Sarraj, Chadi Saad, Eleni Fethnou, Fatima Qafoud, Eiman Alkhayat, Nahla Afifi, Sara Tomei, Wei Liu, Stephan Lorenz, Hakeem Almabrazi, Fazulur R Vempalli, Tariq Abu Saqri, Mohammedhusen Khatib, Mehshad Hamza, Tariq Abu Zaid, Ahmed El Khouly, Tushar Pathare, Shafeeq Poolat, Rashid Al-Ali, Omar Albagha, Souhaila Al-Khodor, Mashael Alshafai, Ramin Badii, Xavier Estivill, Khalid Fakhro, Jithesh V Puthen, Karsten Suhre, Zohreh Tatari
Publikováno v:
The Lancet. Oncology. 23(3)
Background: Disparities in the genetic risk of cancer among various ancestry groups and populations remain poorly defined. This challenge is even more acute for Middle Eastern populations, where the paucity of genomic data could affect the clinical p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbce6fdfc5ac4b7b3692e3302e11ded
https://pubmed.ncbi.nlm.nih.gov/35150602
https://pubmed.ncbi.nlm.nih.gov/35150602
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138006 (2015)
Transcriptomes are one of the first sources of high-throughput genomic data that have benefitted from the introduction of Next-Gen Sequencing. As sequencing technology becomes more accessible, transcriptome sequencing is applicable to multiple organi
Externí odkaz:
https://doaj.org/article/a119408790ad48f4b2f70f9a98d718df