Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ramyani, De"'
Autor:
Selwyn J. Hurwitz, Ramyani De, Julia C. LeCher, Jessica A. Downs-Bowen, Shu Ling Goh, Keivan Zandi, Tamara McBrayer, Franck Amblard, Dharmeshkumar Patel, James J. Kohler, Manoj Bhasin, Brian S. Dobosh, Vikas Sukhatme, Rabindra M. Tirouvanziam, Raymond F. Schinazi
Publikováno v:
Viruses, Vol 16, Iss 4, p 651 (2024)
Most repurposed drugs have proved ineffective for treating COVID-19. We evaluated median effective and toxic concentrations (EC50, CC50) of 49 drugs, mostly from previous clinical trials, in Vero cells. Ratios of reported unbound peak plasma concentr
Externí odkaz:
https://doaj.org/article/954d72f36177427d91cc4fd8c5a0b6f5
Autor:
Nicolas G. Biteau, Sarah A. Amichai, Niloufar Azadi, Ramyani De, Jessica Downs-Bowen, Julia C. Lecher, Tamara MacBrayer, Raymond F. Schinazi, Franck Amblard
Publikováno v:
Viruses, Vol 15, Iss 2, p 544 (2023)
Over the past decades, both 4′-modified nucleoside and carbocyclic nucleoside analogs have been under the spotlight as several compounds from either family showed anti-HIV, HCV, RSV or SARS-CoV-2 activity. Herein, we designed compounds combining th
Externí odkaz:
https://doaj.org/article/fe6511c73d1e4e1d9ca07bed6f63f6f0
Autor:
Julia C. LeCher, Keivan Zandi, Vivian Vasconcelos Costa, Franck Amblard, Sijia Tao, Dharmeshkumar Patel, Sujin Lee, Felipe Rocha da Silva Santos, Matheus Rodrigues Goncalves, Celso Martins Queroz-Junior, Fernanda Martins Marim, Katie Musall, Shu Ling Goh, Tamara McBrayer, Jessica Downs-Bowen, Ramyani De, Niloufar Azadi, James Kohler, Mauro Martins Teixeira, Raymond F. Schinazi
Publikováno v:
Microorganisms, Vol 10, Iss 11, p 2098 (2022)
Yellow fever virus (YFV) is a potentially lethal, zoonotic, blood-borne flavivirus transmitted to humans and non-human primates by mosquitoes. Owing to multiple deadly epidemics, the WHO classifies YFV as a “high impact, high threat disease” with
Externí odkaz:
https://doaj.org/article/b7afa49fb6e74c87b2b2be789d66b3e8
Autor:
Franck Amblard, Julia C. LeCher, Ramyani De, Shu Ling Goh, Chengwei Li, Mahesh Kasthuri, Nicolas Biteau, Longhu Zhou, Zahira Tber, Jessica Downs-Bowen, Keivan Zandi, Raymond F. Schinazi
Publikováno v:
Pharmaceuticals, Vol 15, Iss 9, p 1144 (2022)
Coronavirus disease 2019 (COVID-19) is an emerging global pandemic with severe morbidity and mortality caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Molnupiravir, an ester prodrug form of N4-hydroxycytidine (NHC), was re
Externí odkaz:
https://doaj.org/article/5b28f39250b449959a136cc3c1d06f07
Autor:
Franck, Amblard, Julia C, LeCher, Ramyani, De, Shu Ling, Goh, Chengwei, Li, Mahesh, Kasthuri, Nicolas, Biteau, Longhu, Zhou, Zahira, Tber, Jessica, Downs-Bowen, Keivan, Zandi, Raymond F, Schinazi
Publikováno v:
Pharmaceuticals (Basel, Switzerland). 15(9)
Coronavirus disease 2019 (COVID-19) is an emerging global pandemic with severe morbidity and mortality caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Molnupiravir, an ester prodrug form of