Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ramya Vishnubhotla"'
Autor:
Nicolette Driscoll, Richard E. Rosch, Brendan B. Murphy, Arian Ashourvan, Ramya Vishnubhotla, Olivia O. Dickens, A. T. Charlie Johnson, Kathryn A. Davis, Brian Litt, Danielle S. Bassett, Hajime Takano, Flavia Vitale
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Driscoll, Rosch et al. design transparent graphene-based surface probes to achieve simultaneous electrophysiological recording and calcium imaging of epileptic seizures in mice. This method could be used to investigate circuit dynamics during seizure
Externí odkaz:
https://doaj.org/article/f932d6cf433744e78a90d1a0559256c2
Autor:
Ramya Vishnubhotla, Jinglei Ping, Zhaoli Gao, Abigail Lee, Olivia Saouaf, Amey Vrudhula, A. T. Charlie Johnson
Publikováno v:
AIP Advances, Vol 7, Iss 11, Pp 115111-115111-6 (2017)
Simpler and more rapid approaches for therapeutic drug-level monitoring are highly desirable to enable use at the point-of-care. We have developed an all-electronic approach for detection of the HIV drug tenofovir based on scalable fabrication of arr
Externí odkaz:
https://doaj.org/article/667ccf352a1e4c7297320cd3836d0546
Autor:
Gregory R. Wiedman, Yanan Zhao, Arkady Mustaev, Jinglei Ping, Ramya Vishnubhotla, A. T. Charlie Johnson, David S. Perlin
Publikováno v:
mSphere, Vol 2, Iss 4 (2017)
ABSTRACT This technical report describes the development of an aptamer for sensing azole antifungal drugs during therapeutic drug monitoring. Modified synthetic evolution of ligands through exponential enrichment (SELEX) was used to discover a DNA ap
Externí odkaz:
https://doaj.org/article/1a0982c96d9845778937c111a453bd6f
Publikováno v:
Langmuir. 37:2607-2618
Conformational changes of single-stranded DNA (ssDNA) play an important role in a DNA strand's ability to bind to target ligands. A variety of factors can influence conformation, including temperature, ionic strength, pH, buffer cation valency, stran
Autor:
Ramya Vishnubhotla, Emmeline Adu-Beng, Jinglei Ping, A. T. Charlie Johnson, Adithya Sriram, Srinivas V. Mandyam, Olivia O. Dickens
Publikováno v:
IEEE Sensors Journal. 20:5720-5724
Graphene-based biosensors can be produced in a scalable manner at reasonable cost, and they show significant promise for sensitive detection of small molecules and biomarkers such as proteins, single strand nucleic acids, and drug targets. Here, we d
Autor:
A. T. Charlie Johnson, Ramya Vishnubhotla, Danielle S. Bassett, Brendan B. Murphy, Richard E. Rosch, Brian Litt, Nicolette Driscoll, Arian Ashourvan, Hajime Takano, Flavia Vitale, Olivia O. Dickens, Kathryn A. Davis
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Neurological disorders such as epilepsy arise from disrupted brain networks. Our capacity to treat these disorders is limited by our inability to map these networks at sufficient temporal and spatial scales to target interventions. Current best techn
Autor:
Ramya Vishnubhotla, Flavia Vitale, Brian Litt, Nicolette Driscoll, Hajime Takano, Olivia O. Dickens, Brendan B. Murphy, A. T. Charlie Johnson, Arian Ashourvan, Kathryn A. Davis, Richard E. Rosch, Danielle S. Bassett
Neurological disorders such as epilepsy arise from disrupted brain networks. Our capacity to treat these disorders is limited by our inability to map these networks at sufficient temporal and spatial scales to target interventions. Current best techn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::391e99b62ce348dc5ecc7a6e23591f7e
https://doi.org/10.1101/2020.06.04.134189
https://doi.org/10.1101/2020.06.04.134189
Autor:
Ramya Vishnubhotla, Pedro Ducos, Alan T. Johnson, Jinglei Ping, Jeffery G. Saven, Jin Xi, Renyu Liu
Publikováno v:
ACS Nano. 12:4218-4223
Opioid neuropeptides play a significant role in pain perception, appetite regulation, sleep, memory, and learning. Advances in understanding of opioid peptide physiology are held back by the lack of methodologies for real-time quantification of affin
Publikováno v:
ECS Meeting Abstracts. :1687-1687
Introduction Electrochemical biosensors can offer rapid, scalable, and inexpensive biological and chemical detection compared to more traditional measurement techniques. These devices can sense the presence of drugs for therapeutic drug monitoring or
Publikováno v:
ACS Nano
Scalable production of all-electronic DNA biosensors with high sensitivity and selectivity is a critical enabling step for research and applications associated with detection of DNA hybridization. We have developed a scalable and very reproducible (>