Mannose-conjugated chitosan nanoparticles for delivery of Rifampicin to Osteoarticular tuberculosis

Autor: Pramila Chaubey, Ramya Vk, Parvinder Kaur, Sujata P. Sawarkar, Trinette Fernandes, Shridhar Narayanan, Pratiksha Prabhu

Publikováno v: Drug delivery and translational research. 11(4)

Tuberculosis (TB) is a potentially fatal contagious disease and is a second leading infectious cause of death in the world. Osteoarticular TB is treated using standard regimen of 1st and 2nd line anti-tubercular drugs (ATDs) for extensive period of 8

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https://pubmed.ncbi.nlm.nih.gov/34021478

Discovery of Species-Specific Proteotypic Peptides To Establish a Spectral Library Platform for Identification of Nontuberculosis Mycobacteria from Mass Spectrometry-Based Proteomics.

Autor: Kotimoole CN; Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore 575018, India., Ramya VK; Foundation for Neglected Disease Research, 20A, KIADB Industrial Area, Veerapura Village, Doddaballapur, Bengaluru 561203, India., Kaur P; Foundation for Neglected Disease Research, 20A, KIADB Industrial Area, Veerapura Village, Doddaballapur, Bengaluru 561203, India., Reiling N; Microbial Interface Biology, Research Center Borstel, Leibniz Lung Center, Parkallee 22, D-23845 Borstel, Germany.; German Center for Infection Research (DZIF), Site Hamburg-Lübeck-Borstel-Riems, 23845 Borstel, Germany., Shandil RK; Foundation for Neglected Disease Research, 20A, KIADB Industrial Area, Veerapura Village, Doddaballapur, Bengaluru 561203, India., Narayanan S; Foundation for Neglected Disease Research, 20A, KIADB Industrial Area, Veerapura Village, Doddaballapur, Bengaluru 561203, India., Flo TH; Centre of Molecular Inflammation Research, Department of Clinical and Molecular Medicine Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Kunnskapssenteret, Øya 424.04.035, Norway., Prasad TSK; Center for Systems Biology and Molecular Medicine, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore 575018, India.

Publikováno v: Journal of proteome research [J Proteome Res] 2024 Mar 01; Vol. 23 (3), pp. 1102-1117. Date of Electronic Publication: 2024 Feb 15.

Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA Gyrase B.

Autor: Kale MG; Department of Medicinal Chemistry, ‡Department of Biosciences, and §DMPK and Animal Sciences, AstraZeneca India Pvt. Ltd. , Bellary Road, Hebbal, Bangalore 560024, India., Raichurkar A, P SH, Waterson D, McKinney D, Manjunatha MR, Kranthi U, Koushik K, Jena Lk, Shinde V, Rudrapatna S, Barde S, Humnabadkar V, Madhavapeddi P, Basavarajappa H, Ghosh A, Ramya VK, Guptha S, Sharma S, Vachaspati P, Kumar KN, Giridhar J, Reddy J, Panduga V, Ganguly S, Ahuja V, Gaonkar S, Kumar CN, Ogg D, Tucker JA, Boriack-Sjodin PA, de Sousa SM, Sambandamurthy VK, Ghorpade SR

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2013 Nov 14; Vol. 56 (21), pp. 8834-48. Date of Electronic Publication: 2013 Oct 18.

Aminopyrazinamides: novel and specific GyrB inhibitors that kill replicating and nonreplicating Mycobacterium tuberculosis.

Autor: Shirude PS; Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd., Bellary Road, Hebbal, Bangalore 560024, India. pravin.shirude@astrazeneca.com, Madhavapeddi P, Tucker JA, Murugan K, Patil V, Basavarajappa H, Raichurkar AV, Humnabadkar V, Hussein S, Sharma S, Ramya VK, Narayan CB, Balganesh TS, Sambandamurthy VK

Publikováno v: ACS chemical biology [ACS Chem Biol] 2013 Mar 15; Vol. 8 (3), pp. 519-23. Date of Electronic Publication: 2012 Dec 31.