Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ramya Sundaresan"'
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3728-3739 (2017)
CRISPR-Cas systems provide bacteria and archaea with sequence-specific protection against invading mobile genetic elements. In the presence of divalent metal ions, Cas9 and Cas12a (formerly Cpf1) proteins target and cleave DNA that is complementary t
Externí odkaz:
https://doaj.org/article/8f5a8f6dc6e24c118b47d10b06d12b5b
Autor:
Cheng-Guo Wu, Vijaya K. Balakrishnan, Pankaj S. Parihar, Kirill Konovolov, Yu-Chia Chen, Ronald A Merrill, Hui Wei, Bridget Carragher, Ramya Sundaresan, Qiang Cui, Brian E. Wadzinski, Mark R. Swingle, Alla Musiyenko, Richard Honkanen, Wendy K. Chung, Aussie Suzuki, Stefan Strack, Xuhui Huang, Yongna Xing
An increasing number of mutations associated with devastating human diseases are diagnosed by whole-genome/exon sequencing. Recurrentde novomissense mutations have been discovered in B56δ (encoded byPPP2R5D), a regulatory subunit of protein phosphat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8c7723ac5bfc49c8706fa023d5ad09e
https://doi.org/10.1101/2023.03.09.530109
https://doi.org/10.1101/2023.03.09.530109
Autor:
Hari Priya Parameshwaran, S. D. Yogesha, Mark Walter Keilbarth, Ramya Sundaresan, Rakhi Rajan
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3728-3739 (2017)
Cell reports
Cell reports
SUMMARY CRISPR-Cas systems provide bacteria and archaea with sequence-specific protection against invading mobile genetic elements. In the presence of divalent metal ions, Cas9 and Cas12a (formerly Cpf1) proteins target and cleave DNA that is complem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6235ec23951d8719b94d303a82621333
http://www.sciencedirect.com/science/article/pii/S2211124717317849
http://www.sciencedirect.com/science/article/pii/S2211124717317849
Publikováno v:
Molecular Cell. 68:15-25
CRISPR–Cas systems defend prokaryotes against bacteriophages and mobile genetic elements and serve as the basis for revolutionary tools for genetic engineering. Class 2 CRISPR–Cas systems use single Cas endonucleases paired with guide RNAs to cle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c0ccbf056edce1fde82adc55300ed9
https://doi.org/10.1016/j.molcel.2017.09.007
https://doi.org/10.1016/j.molcel.2017.09.007
Publikováno v:
International Journal of Biological Macromolecules. 75:97-105
The serine rich repeat protein-1 (Srr-1) is an adhesive protein of Streptococcus agalactiae. It is the first bacterial protein identified to interact with human keratin 4 (K4 or KRT4). Within Srr-1, the residues 311-641 constitute the non-repeat liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce220a06a4ade07a61eae4d0d6d1cb41
https://doi.org/10.1016/j.ijbiomac.2014.12.048
https://doi.org/10.1016/j.ijbiomac.2014.12.048
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 67:1582-1585
Serine-rich repeat protein 1 (Srr-1) is a surface protein from Streptococcus agalactiae. A 17 kDa region of this protein has been identified to bind to human keratin 4 (K4) and is termed the Srr-1 K4-binding domain (Srr-1-K4BD). Recombinant Srr-1-K4B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7108cae91c9f025600a03c3bcf5809c4
https://doi.org/10.1107/s1744309111040413
https://doi.org/10.1107/s1744309111040413
Autor:
Ramya Sundaresan, Thirumananseri Kumarevel, Karthe Ponnuraj, Shigeyuki Yokoyama, Seiki Kuramitsu, Akio Ebihara
Publikováno v:
Biochemical and biophysical research communications. 465(2)
The enzymatic biosynthesis of l -arginine involves complex, sequential action of many enzymes and ornithine transcarbamylase (OTCase) is one of the essential enzymes in the pathway. In mammals OTCase is part of the urea cycle. Arginine is used in a v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083718ad5b575580b23ee3068a8c8ffb
https://pubmed.ncbi.nlm.nih.gov/26210451
https://pubmed.ncbi.nlm.nih.gov/26210451
Autor:
Ramya Sundaresan, Shigeyuki Yokoyama, Karthe Ponnuraj, Seiki Kuramitsu, Thirumananseri Kumarevel, Preethi Ragunathan
Publikováno v:
Biochemical and biophysical research communications. 420(3)
The de novo biosynthesis of arginine in microorganisms and plants is accomplished via several enzymatic steps. The enzyme N -acetyl glutamate kinase (NAGK) catalyzes the phosphorylation of the γ-COO − group of N -acetyl- l -glutamate (NAG) by aden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4382216ab187c89de9f05dbf896c7f2
https://pubmed.ncbi.nlm.nih.gov/22452987
https://pubmed.ncbi.nlm.nih.gov/22452987
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 25:S94-S94
Acute inflammation contributes to brain damage after focal cerebral ischemia. Although several transcription factors are known to be upregulated in the post-ischemic brain, the role of transcriptional events in controlling cerebral inflammation is no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fdc87290bec3a55134863684677fbee
https://doi.org/10.1038/sj.jcbfm.9591524.0094
https://doi.org/10.1038/sj.jcbfm.9591524.0094