Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ramya Sundararajan"'
Autor:
Laurie H. Sanders, Josée Laganière, Oliver Cooper, Sally K. Mak, B. Joseph Vu, Y. Anne Huang, David E. Paschon, Malini Vangipuram, Ramya Sundararajan, Fyodor D. Urnov, J. William Langston, Philip D. Gregory, H. Steve Zhang, J. Timothy Greenamyre, Ole Isacson, Birgitt Schüle
Publikováno v:
Neurobiology of Disease, Vol 62, Iss , Pp 381-386 (2014)
Parkinson's disease associated mutations in leucine rich repeat kinase 2 (LRRK2) impair mitochondrial function and increase the vulnerability of induced pluripotent stem cell (iPSC)-derived neural cells from patients to oxidative stress. Since mitoch
Externí odkaz:
https://doaj.org/article/d505d3408a924944819f08f5874cf168
Autor:
Sally K. Mak, Y. Anne Huang, Shifteh Iranmanesh, Malini Vangipuram, Ramya Sundararajan, Loan Nguyen, J. William Langston, Birgitt Schüle
Publikováno v:
Stem Cells International, Vol 2012 (2012)
Efficient in vitro differentiation into specific cell types is more important than ever after the breakthrough in nuclear reprogramming of somatic cells and its potential for disease modeling and drug screening. Key success factors for neuronal diffe
Externí odkaz:
https://doaj.org/article/27d029443e384e9a9aa730c624be3d06
Autor:
Reshma Kumar, Mingkuan Lin, Raja Parasuraman, Ramya Sundararajan, Karl J. Fryxell, Pamela M. Greenwood
Publikováno v:
Journal of Cognitive Neuroscience. 21:2139-2153
We investigated the relation between the two systems of visuospatial attention and working memory by examining the effect of normal variation in cholinergic and noradrenergic genes on working memory performance under attentional manipulation. We prev
Publikováno v:
Proceedings of the National Academy of Sciences. 106:3633-3638
It is widely appreciated that neurotransmission systems interact in their effects on human cognition, but those interactions have been little studied. We used genetics to investigate pharmacological evidence of synergisms in nicotinic/muscarinic inte
Publikováno v:
Oncogene. 24:4908-4920
Deleted in breast cancer-1 (DBC-1) was initially cloned from a homozygously deleted region in breast and other cancers on human chromosome 8p21, although no function is known for the protein product it encodes. We identified the generation of amino-t
Publikováno v:
Journal of Biological Chemistry. 277:14127-14134
Pro-apoptotic Bax and Bak have been implicated in the regulation of p53-dependent apoptosis. We assessed the ability of primary baby mouse kidney (BMK) epithelial cells from bax(-/-), bak(-/-), and bax(-/-) bak(-/-) mice to be transformed by E1A alon
Autor:
Eileen White, Ramya Sundararajan
Publikováno v:
Journal of Virology. 75:7506-7516
Tumor necrosis factor alpha (TNF-α)-mediated death signaling causes the recruitment of monomeric pro- apoptotic Bax into a 500-kDa protein complex. The adenovirus Bcl-2 homologue, E1B 19K, inhibits TNF-α-mediated apoptosis, interacts with Bax, and
Autor:
H. Steve Zhang, Josee Laganiere, Philip D. Gregory, B. Joseph Vu, Y. Anne Huang, Sally K. Mak, David Paschon, Birgitt Schüle, J. Timothy Greenamyre, Ramya Sundararajan, Fyodor D. Urnov, Malini Vangipuram, J. William Langston, Laurie H. Sanders, Oliver Cooper, Ole Isacson
Publikováno v:
Neurobiology of Disease, Vol 62, Iss, Pp 381-386 (2014)
Parkinson's disease associated mutations in leucine rich repeat kinase 2 (LRRK2) impair mitochondrial function and increase the vulnerability of induced pluripotent stem cell (iPSC)-derived neural cells from patients to oxidative stress. Since mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54da75b1fafd8e00f22eea6ef429a641
https://europepmc.org/articles/PMC3877733/
https://europepmc.org/articles/PMC3877733/
Autor:
J. William Langston, Loan Nguyen, Ramya Sundararajan, Y. Anne Huang, Birgitt Schüle, Sally K. Mak, Shifteh Iranmanesh, Malini Vangipuram
Publikováno v:
Stem Cells International, Vol 2012 (2012)
Stem Cells International
Stem Cells International
Efficientin vitrodifferentiation into specific cell types is more important than ever after the breakthrough in nuclear reprogramming of somatic cells and its potential for disease modeling and drug screening. Key success factors for neuronal differe
Publikováno v:
Journal of virology. 76(9)
Adenovirus infection and expression of E1A induces both proliferation and apoptosis, the latter of which is blocked by the adenovirus Bcl-2 homologue E1B 19K. The mechanism of apoptosis induction and the role that it plays in productive infection are