Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ramya Sridharan"'
Autor:
Arianna R. Izawa-Ishiguro, Ramya Sridharan, Christopher Wun, Tabassum J. Sami, Daniel A. Heller
Publikováno v:
Cancer Research. 82:302-302
Targeting oncogenic signaling in the MAPK pathway can be achieved with small molecules such as trametinib, a MEK inhibitor (MEKi). Trametinib-induced MEK inhibition in KRAS-mutant (KRASmt) lung cancer, however, results in compensatory MAPK pathway re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fc38c8e0baf73cf01f369e3fe71a892
https://doi.org/10.1158/1538-7445.am2022-302
https://doi.org/10.1158/1538-7445.am2022-302
Autor:
Scott W. Lowe, Elisa de Stanchina, Josef Leibold, Ramya Sridharan, John E. Wilkinson, Robert J. Norgard, Daniel A. Heller, Myles Fennell, John P. Morris, Paul B. Romesser, James A. Russell, Jinyang Li, Ben Z. Stanger, Charles J. Sherr, Riccardo Mezzadra, Amanda Kulick, Janelle Simon, Direna Alonso-Curbelo, Yu-Jui Ho, Marcus Ruscetti
Publikováno v:
Cell
Summary KRAS mutant pancreatic ductal adenocarcinoma (PDAC) is characterized by a desmoplastic response that promotes hypovascularity, immunosuppression, and resistance to chemo- and immunotherapies. We show that a combination of MEK and CDK4/6 inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d6685e65c0fdc86be5f8a16289599f
https://pubmed.ncbi.nlm.nih.gov/34478658
https://pubmed.ncbi.nlm.nih.gov/34478658
Autor:
Sarah E. Poplawski, David G. Sanford, Mitchell S. Wang, Eun Bin Go, Daniel A. Bachovchin, William W. Bachovchin, Yuxin Liu, Darren C. Johnson, Michael O Arciprete, Ramya Sridharan, Ashley J. Chui, Wengen Wu, Marian C. Okondo, Todd R. Golub, Jack H. Lai
Publikováno v:
Nature Chemical Biology. 13:46-53
Val-boroPro (Talabostat, PT-100), a nonselective inhibitor of post-proline cleaving serine proteases, stimulates mammalian immune systems through an unknown mechanism of action. Despite this lack of mechanistic understanding, Val-boroPro has attracte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3162659cf671c421e083a92883e1885
https://doi.org/10.1038/nchembio.2229
https://doi.org/10.1038/nchembio.2229
Autor:
Josef Leibold, Daniel A. Heller, Jinyang Li, Charles J. Sherr, Ben Z. Stanger, Myles Fennell, Riccardo Mezzadra, Xiang Li, Yu-Jui Ho, Marcus Ruscetti, John P. Morris, Elisa de Stanchina, Robert J. Norgard, Scott W. Lowe, Ramya Sridharan, John E. Wilkinson, Direna Alonso-Curbelo, Janelle Simon, Paul B. Romesser, James A. Russell, Amanda Kulick
Publikováno v:
Cancer Research. 79:PR01-PR01
Background: KRAS mutant pancreatic ductal adenocarcinoma (PDAC) is characterized by a desmoplastic response that promotes hypovascularity, poor drug delivery, immunosuppression, and de novo resistance to chemo- and immunotherapies. Recently, we demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64a582780ba1fb5e9a2f54cbef9bdd9c
https://doi.org/10.1158/1538-7445.panca19-pr01
https://doi.org/10.1158/1538-7445.panca19-pr01
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebe81ee662afc780bb20c31345707e00
https://doi.org/10.1096/fasebj.2018.32.1_supplement.801.10
https://doi.org/10.1096/fasebj.2018.32.1_supplement.801.10
Autor:
Josef Leibold, Januka Budhathoki-Uprety, Michelle R. Neiman, Vinagolu K. Rajasekhar, Ramya Sridharan, Yosi Shamay, James L. Sugarman, Daniel Roxbury, Janki Shah, Emily Baut, Megan M. Dacek, John D. Chodera, Karen L. Chu, Kripa S. Ganesh, Mehtap Işık, Darjus F. Tschaharganeh, Aviram Mizrachi, Darren C. Johnson, Scott W. Lowe, Daniel A. Heller, Karla Nawaly
Publikováno v:
Nature materials
Development of targeted nanoparticle drug carriers often requires complex synthetic schemes involving both supramolecular self-assembly and chemical modification. These processes are generally difficult to predict, execute, and control. We describe h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5267dd2cbd5618b2b767b4bbcd9d16e
https://pubmed.ncbi.nlm.nih.gov/29860981
https://pubmed.ncbi.nlm.nih.gov/29860981
Publikováno v:
The FASEB Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::379a974b29f58ee5e0ef90fc4764fc95
https://doi.org/10.1096/fasebj.28.1_supplement.835.6
https://doi.org/10.1096/fasebj.28.1_supplement.835.6
Autor:
Ramya Sridharan, E.C. Prakash
Publikováno v:
Proceedings of the Fourth IEEE International Symposium on Signal Processing and Information Technology, 2004..
Visual image processing is extensively used in the field of medicine and biomedical engineering. It has two major divisions: analysis and synthesis, (i) analysis refers to the extraction and quantification of data from available images, (ii) synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8024b3587c813f835bdd12b4467e4ebb
https://doi.org/10.1109/isspit.2004.1433685
https://doi.org/10.1109/isspit.2004.1433685
Autor:
Ramya Sridharan
Visual Image Processing is extensively used in the field of medicine and bio-medical engineering. It has become almost indispensable in many bio-medical applications. Visual image processing has two major divisions: Analysis and Synthesis. (i) Analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1392::d267dc03b41b2aeab8090994a1387631
http://hdl.handle.net/10356/6310
http://hdl.handle.net/10356/6310
