Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Ramya Sivangala"'
Autor:
Ramya Sivangala Thandi, Rajesh Kumar Radhakrishnan, Deepak Tripathi, Padmaja Paidipally, Abul K. Azad, Larry S. Schlesinger, Buka Samten, Sachin Mulik, Ramakrishna Vankayalapati
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Kupffer cells are more resistant to M. tuberculosis when compared with alveolar macrophages. Here the authors show that this distinction is caused by the presence of ornithine and imidazole in Kupffer cells and that these metabolites can drive autoph
Externí odkaz:
https://doaj.org/article/f17c1a1cefad4df6a818b7dcf60e439b
Autor:
Ramya Sivangala Thandi, Rajesh Kumar Radhakrishnan, Deepak Tripathi, Padmaja Paidipally, Abul K. Azad, Larry S. Schlesinger, Buka Samten, Sachin Mulik, Ramakrishna Vankayalapati
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/7a62c2db10cd44e98a1eb04903a47d78
Autor:
Deepak Tripathi, Rajesh Kumar Radhakrishnan, Ramya Sivangala Thandi, Padmaja Paidipally, Kamakshi Prudhula Devalraju, Venkata Sanjeev Kumar Neela, Madeline Kay McAllister, Buka Samten, Vijaya Lakshmi Valluri, Ramakrishna Vankayalapati
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009578 (2021)
[This corrects the article DOI: 10.1371/journal.ppat.1008140.].
Externí odkaz:
https://doaj.org/article/5bfe595fc3af4efcaa9740bad18880da
Autor:
Deepak Tripathi, Rajesh Kumar Radhakrishnan, Ramya Sivangala Thandi, Padmaja Paidipally, Kamakshi Prudhula Devalraju, Venkata Sanjeev Kumar Neela, Madeline Kay McAllister, Buka Samten, Vijaya Lakshmi Valluri, Ramakrishna Vankayalapati
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008140 (2019)
Previously, we found that pathological immune responses enhance the mortality rate of Mycobacterium tuberculosis (Mtb)-infected mice with type 2 diabetes mellitus (T2DM). In the current study, we evaluated the role of the cytokine IL-22 (known to pla
Externí odkaz:
https://doaj.org/article/f93ba82150a045c2beb975e533bc75d2
Autor:
Lavanya Joshi, Meenakshi Ponnana, Ramya Sivangala, Lakshmi Kiran Chelluri, Prathiba Nallari, Sitaramaraju Penmetsa, Vijayalakshmi Valluri, Sumanlatha Gaddam
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137727 (2015)
BackgroundHousehold contacts of diagnostically established tuberculosis (TB) patients are highly susceptible to disease development. It is surmised that cytokines perhaps play a synergistic and a prognostic role in the activation of the otherwise lat
Externí odkaz:
https://doaj.org/article/12310bc5fab24461a9377286e5f3e153
Autor:
Ronald Benjamin, Atoshi Banerjee, Kannan Balakrishnan, Ramya Sivangala, Sumanlatha Gaddam, Sharmistha Banerjee
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104908 (2014)
BACKGROUND: Concurrent occurrence of HIV and Tuberculosis (TB) infections influence the cellular environment of the host for synergistic existence. An elementary approach to understand such coalition at the molecular level is to understand the intera
Externí odkaz:
https://doaj.org/article/281d48b7a8d54de3a6076d1d2fad115a
Autor:
Larry S. Schlesinger, Ramya Sivangala Thandi, Rajesh Kumar Radhakrishnan, Padmaja Paidipally, Abul K. Azad, Deepak Tripathi, Ramakrishna Vankayalapati, Buka Samten, Sachin Mulik
Publikováno v:
Nature Communications. 11
Macrophages are professional phagocytes known to play a vital role in controlling Mycobacterium tuberculosis (Mtb) infection and disease progression. Here we compare Mtb growth in mouse alveolar (AMs), peritoneal (PMs), and liver (Kupffer cells; KCs)
Autor:
Padmaja Paidipally, Deepak Tripathi, Buka Samten, Madeline Kay McAllister, Ramya Sivangala Thandi, Sachin Mulik, Ramakrishna Vankayalapati, Rajesh Kumar Radhakrishnan
Publikováno v:
JCI Insight. 5
Diabetes is a significant risk factor for the development of active tuberculosis. In this study, we used a mouse model of type 2 diabetes mellitus (T2DM) to determine the effect of prior Bacillus Calmette-Guérin (BCG) vaccination on immune responses
Autor:
Ramakrishna Vankayalapati, Satyanarayana S. Cheekatla, Amy R. Tvinnereim, Rajesh Kumar Radhakrishnan, Ramya Sivangala Thandi, Padmaja Paidipally, Deepak Tripathi, Elwyn Welch
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
CD4+CD25+FoxP3+ cells (Tregs) inhibit inflammatory immune responses to allografts. Here, we found that co-transplantation of allogeneic pancreatic islets with Tregs that are defective in c-Jun N-terminal kinase 1 (JNK1) signaling prolongs islet allog
Autor:
Sumanlatha Gaddam, Rajashekar Myakala, Jyothi Priya Mandala, Ramya Sivangala, Meenakshi Ponnana, Shruthi Thada
Publikováno v:
Immunobiology. 226:152096
Purpose The immune response induced by nucleotide-binding oligomerization domain-2(NOD2) is associated with the production of cytokines affected by the host's genetic background. The present study aimed to examine the effects of NOD2; 802C > T, 2105G