Výsledky vyhledávání - "Ramya Kongala"

Akademický článek

T Cell Repertoire Homogeneity and Blood-Gut Overlap in Patients With Inflammatory Bowel DiseaseSummary

Autor: Kyle G. Williams, Ramya Kongala, Donna M. Shows, Andrew J. Konecny, Duncan C. Hindmarch, Astrid S. Clarke, James D. Lord

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 1, Pp 119-130 (2024)

Background & Aims: Inflammatory bowel disease (IBD) causes a marked increase in the number of T cells in the intestinal mucosa. Debate exists about whether these excess cells arise from local clonal proliferation or recruitment from the periphery. Me

Externí odkaz: https://doaj.org/article/ee9454018c844a7b80fe3559c671e348

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THE EFFECT OF VEDOLIZUMAB ON CD8 T CELL REPERTOIRE HOMOGENEITY AND BLOOD-GUT TRAFFICKING IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE

Autor: Kyle Williams, Donna Shows, Ramya Kongala, Duncan Hindmarch, Astrid Clarke, James Lord

Publikováno v: Inflammatory Bowel Diseases. 29:S80-S81

BACKGROUND Inflammatory bowel disease (IBD) causes T cell infiltration of the intestinal mucosa, but the heterogeneity of these cells is not understood at a clonal level. The drug vedolizumab is believed to treat IBD by blocking the entry of circulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed444c7bd29885b09ecfca3f779c4d7
https://doi.org/10.1093/ibd/izac247.154

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VEDOLIZUMAB REDUCES DENDRITIC CELLS AND NAÏVE LYMPHOCYTES IN THE COLON MUCOSA

Autor: James D Lord, Ramya Kongala, Julius Juarez

Publikováno v: The Journal of Immunology. 208:48.14-48.14

Vedolizumab blocks integrin alpha4/beta7 interaction with MAdCAM-1 on intestinal vascular endothelial cells. It is believed to treat inflammatory bowel disease (IBD) by preventing alpha4/beta7+ cells in blood from entering the intestinal mucosa. By C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12e528f231bad9b2ee44ca5af4567f94
https://doi.org/10.4049/jimmunol.208.supp.48.14

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