Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ramu Meesala"'
Publikováno v:
Marine Drugs, Vol 20, Iss 9, p 579 (2022)
A marine natural product possesses a diverse and unique scaffold that contributes to a vast array of bioactivities. Tricyclic guanidine alkaloids are a type of scaffold found only in marine natural products. These rare skeletons exhibit a wide range
Externí odkaz:
https://doaj.org/article/88591b1287b747ca9db1ecd5cf782c2c
Autor:
Noorsaadah Abd Rahman, Yean Kee Lee, Ramu Meesala, Iskandar Abdullah, Mohd Nizam Mordi, Ahmad Saifuddin Mohamad Arshad
Publikováno v:
Synlett. 31:2054-2058
A facile synthesis of various 2-(carbazolyl)benzothiazoles has been developed by one-pot CuBr-catalyzed three-component reactions of 2-iodoanilines, arylaldehydes, and elemental sulfur. Unlike traditional approach, this reaction exhibited a good func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::762856b9ff5759954de20ec8bd2786ee
https://doi.org/10.1055/s-0040-1706477
https://doi.org/10.1055/s-0040-1706477
Autor:
Subramanian Baskaran, Ramu Meesala, Bing Xia, Robert Hamatake, George Adjabeng, Wieslaw M. Kazmierski, Katja Remlinger, Martin Robert Leivers, Renae M. Crosby, Nagaraju Miriyala, Mallesh Beesu, Richard Martin Grimes, Jill Walker
Publikováno v:
Journal of Medicinal Chemistry. 63:4155-4170
Pan-genotype NS5A inhibitors underpin hugely successful hepatitis C virus (HCV) therapy. The discovery of GSK2818713 (13), a nonstructural protein 5A (NS5A) HCV inhibitor characterized by a significantly improved genotype coverage relative to first-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70656693a42713afb662aeea1af42dc
https://doi.org/10.1021/acs.jmedchem.9b02176
https://doi.org/10.1021/acs.jmedchem.9b02176
Publikováno v:
Tetrahedron. 72:8537-8541
A synthetic strategy was developed for the preparation of β-carbolines by one-pot decarboxylation and aromatization of tetrahydro-β-carboline-3-carboxylic acids by employing 10 mol% of iodine in presence of oxidant aqueous H2O2. The method was also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4a9b70b395ad90d3c879e08aba455ad
https://doi.org/10.1016/j.tet.2016.10.069
https://doi.org/10.1016/j.tet.2016.10.069
Autor:
Mohd Nizam Mordi, Sharif Mahsufi Mansor, Ramu Meesala, Ahmad Saifuddin Mohamad Arshad, Mallikarjuna Rao Pichika
Publikováno v:
Synlett. 29:1084-1086
Oxidation of carbazole-3-carboxyaldehydes promoted by a 70% aqueous solution of tert-butylhydroperoxide leads to the corresponding carbazole-3-carboxylic acids in good yields. This transition-metal-free oxidation protocol is attractive for the synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca8e04da6a42ed0e4d4dd256b1fb2e40
https://doi.org/10.1055/s-0036-1591897
https://doi.org/10.1055/s-0036-1591897
Publikováno v:
Tetrahedron. 83:131960
A convenient synthesis for the conversion of various substituted tetrahydro-β-carbolines has been developed by iron-catalyzed decarboxylative/dehydrogenative aromatization to construct aromatic β-carbolines under air atmosphere. In the presence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58539e8b5a1f16bfa1c179be433cfa4d
https://doi.org/10.1016/j.tet.2021.131960
https://doi.org/10.1016/j.tet.2021.131960
Autor:
Suhana Arshad, Nelson Jeng Yeou Chear, Mohammed Oday Ezzat, Mohd Nizam Mordi, Sharif Mahsufi Mansor, Ahmad Saifuddin Mohamad Arshad, Ramu Meesala, Nur Aziah Hanapi
Publikováno v:
Journal of Molecular Structure. 1200:127070
In this study, a new tetrahydro-β-carboline derivative, 2-benzoyl-6-methoxy-9-methyl-1-phenyl-1,2,3,4-tetrahydro-β-carboline has been synthesized through a three-steps reaction in good yield (76%). The structure of this compound was characterized b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3be52f757031556a86845e348fbb97f5
https://doi.org/10.1016/j.molstruc.2019.127070
https://doi.org/10.1016/j.molstruc.2019.127070
Autor:
Mohd Mustaqim Rosli, Nur Azzalia Kamaruzaman, Ramu Meesala, Mohd Nizam Mordi, Mazlin Mohideen, Sharif Mahsufi Mansor
A new compound of 2,9-bis(2-fluorobenzyl)-β-carbolinium bromide, C25H19BrF2N2 has been synthesized by the decarboxylation of ethyl β-carboline-3-carboxylate with 2-fluorobenzyl bromide in the presence of sodium hydride in DMF, with good yield (92%)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6ceb4d8d880339ad605444a6a5d51c
Publikováno v:
Synthetic Communications. 44:1291-1295
An unexpected reduction of indolic double bond of mitragynine was described by using n-butyl silane and tris(pentafluorophenyl)triborane.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5185a16ea070fcfd0efb10f8e79f0cf
https://doi.org/10.1080/00397911.2013.853798
https://doi.org/10.1080/00397911.2013.853798
Publikováno v:
Tetrahedron Letters. 55:7023-7025
The reactions of N -(carbazol-3-yl)acetamides with N , N -dimethylformamide in the presence of phosphorus oxychloride (POCl 3 ) at 90 °C gave the corresponding (carbazol-3-yl)formamidines in good yields. The method is compatible with a variety of fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aea6a60b5574781e51c2c4742980e928
https://doi.org/10.1016/j.tetlet.2014.10.123
https://doi.org/10.1016/j.tetlet.2014.10.123