Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ramses Ayala"'
Autor:
Amy R Noe, Diego Espinosa, Xiangming Li, Jordana G A Coelho-Dos-Reis, Ryota Funakoshi, Steve Giardina, Hongfan Jin, Diane M Retallack, Ryan Haverstock, Jeffrey R Allen, Thomas S Vedvick, Christopher B Fox, Steven G Reed, Ramses Ayala, Brian Roberts, Scott B Winram, John Sacci, Moriya Tsuji, Fidel Zavala, Gabriel M Gutierrez
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107764 (2014)
The circumsporozoite protein (CSP) of Plasmodium falciparum is a major surface protein, which forms a dense coat on the sporozoite's surface. Preclinical research on CSP and clinical evaluation of a CSP fragment-based RTS, S/AS01 vaccine have demonst
Externí odkaz:
https://doaj.org/article/3b2cec5996cd4a34b37c5b812f74c3d6
Autor:
Elizabeth Nardin, Min Zhang, Victor Nussenzweig, Ramses Ayala, Vincent Sahi, Gabriel M. Gutierrez, Robert Mitchell, Xiangming Li, Amy R. Noe, Tiffany Tsao, Raquel Tayar Nogueira, Moriya Tsuji, Ruth S. Nussenzweig, Jordana Grazziela Coelho-dos-Reis, Jing Huang, James M. Wilson
Publikováno v:
Journal of Immunological Methods. 427:42-50
In this study, we developed human immune system (HIS) mice that possess functional human CD4+ T cells and B cells, named HIS-CD4/B mice. HIS-CD4/B mice were generated by first introducing HLA class II genes, including DR1 and DR4, along with genes en
Autor:
Li-Huei Tsai, Anthone W. Dunah, Allison A. Curley, D. Cristopher Bragg, Ramses Ayala, Jay L. Duffner, Lauren R. Kett, Anne B. Young, Lianna R. Orlando
Publikováno v:
Journal of Neurochemistry. 110:557-569
Phosphorylation of neurotransmitter receptors can modify their activity and regulate neuronal excitability. Cyclin-dependent kinase 5 (cdk5) is a proline-directed serine/threonine kinase involved not only in neuronal development, but also in synaptic
Autor:
Ramses Ayala, Sachin Hebbar, Bhavim Desai, Deanna S. Smith, Mariano T. Mesngon, Aimee M. Guillotte
Publikováno v:
The Journal of Cell Biology
Lis1 and Ndel1 are essential for animal development. They interact directly with one another and with cytoplasmic dynein. The developing brain is especially sensitive to reduced Lis1 or Ndel1 levels, as both proteins influence spindle orientation, ne
Autor:
Gernot Neumayer, Su Yeon Shim, Camille Belzil, Minh Dang Nguyen, Benjamin Adam Samuels, Jian Wang, Ramses Ayala, Yujiang Shi, Li-Huei Tsai, Yang Shi
Publikováno v:
Journal of Biological Chemistry. 283:12232-12240
Ndel1, the mammalian homologue of the Aspergillus nidulans NudE, is emergently viewed as an integrator of the cytoskeleton. By regulating the dynamics of microtubules and assembly of neuronal intermediate filaments (IFs), Ndel1 promotes neurite outgr
Publikováno v:
Cell. 128(1):29-43
The correct positioning of neurons during development--achieved through directed migration--is the basis for proper brain function. Several decades of research have yielded a comprehensive map illustrating the temporal and spatial events underlying n
Autor:
Holger Patzke, Janet Volker, Ramses Ayala, Upendra Maddineni, Maria A. Morabito, Michael K. Ahlijanian, Pieter Dikkes, Li-Huei Tsai
Publikováno v:
The Journal of Neuroscience. 23:2769-2778
Cyclin-dependent kinase 5 (Cdk5) is activated on binding of activator proteins p35 and p39. A N-terminally truncated p35, termed p25, is generated through cleavage by the Ca2+-dependent protease calpain after induction of ischemia in rat brain. p25 h
Autor:
Gaurav Arya, Sumeet S. Shroff, Chao Zhang, Ramses Ayala, Ratnesh Lal, Darren Yang, Aereas Aung, Shyni Varghese, Yongsung Hwang, Fernando Teran Arce
Publikováno v:
Biomaterials. 32(15)
The effective utilization of stem cells in regenerative medicine critically relies upon our understanding of the intricate interactions between cells and their extracellular environment. While bulk mechanical and chemical properties of the matrix hav
Publikováno v:
Neuron. 44(2)
Correct neuronal migration and positioning during cortical development are essential for proper brain function. Mutations of the LIS1 gene result in human lissencephaly (smooth brain), which features misplaced cortical neurons and disarrayed cerebral
Autor:
William B. Dobyns, Heather L. Ward, David H. Ledbetter, Li-Huei Tsai, Ramses Ayala, Kazuhito Toyo-oka, Aki Shionoya, Richard J. Leventer, Shinji Hirotsune, Carlos Cardoso, Anthony Wynshaw-Boris, Michael J. Gambello
Publikováno v:
Nature genetics. 34(3)
Heterozygous deletions of 17p13.3 result in the human neuronal migration disorders isolated lissencephaly sequence (ILS) and the more severe Miller-Dieker syndrome (MDS). Mutations in PAFAH1B1 (the gene encoding LIS1) are responsible for ILS and cont