Netrin signaling mediates survival of dormant epithelial ovarian cancer cells.

Autor: Perampalam P; London Regional Cancer Program, London Health Sciences Centre Research Institute, London, Canada.; Department of Biochemistry, University of Western Ontario, London, Canada., MacDonald JI; London Regional Cancer Program, London Health Sciences Centre Research Institute, London, Canada.; Department of Pathology and Laboratory Medicine, University of Western Ontario, London, Canada., Zakirova K; London Regional Cancer Program, London Health Sciences Centre Research Institute, London, Canada.; Department of Pathology and Laboratory Medicine, University of Western Ontario, London, Canada., Passos DT; London Regional Cancer Program, London Health Sciences Centre Research Institute, London, Canada.; Department of Pathology and Laboratory Medicine, University of Western Ontario, London, Canada., Wasif S; London Regional Cancer Program, London Health Sciences Centre Research Institute, London, Canada.; Department of Pathology and Laboratory Medicine, University of Western Ontario, London, Canada., Ramos-Valdes Y; London Regional Cancer Program, London Health Sciences Centre Research Institute, London, Canada.; The Mary and John Knight Translational Ovarian Cancer Research Unit, London Regional Cancer Program, London, Canada., Hervieu M; Apoptosis, Cancer and Development Laboratory - Equipe labellisée 'La Ligue', LabEx DEVweCAN, Institut Convergence PLAsCAN, Centre de Recherche en Cancérologie de Lyon (CRCL), INSERM U1052-CNRS UMR5286, Université de Lyon, Université Claude Bernard Lyon1, Centre Léon Bérard, Lyon, France., Mehlen P; Apoptosis, Cancer and Development Laboratory - Equipe labellisée 'La Ligue', LabEx DEVweCAN, Institut Convergence PLAsCAN, Centre de Recherche en Cancérologie de Lyon (CRCL), INSERM U1052-CNRS UMR5286, Université de Lyon, Université Claude Bernard Lyon1, Centre Léon Bérard, Lyon, France.; Netris Pharma, Lyon, France., Rottapel R; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, 1 King's College Circle, Toronto, Canada., Gibert B; Apoptosis, Cancer and Development Laboratory - Equipe labellisée 'La Ligue', LabEx DEVweCAN, Institut Convergence PLAsCAN, Centre de Recherche en Cancérologie de Lyon (CRCL), INSERM U1052-CNRS UMR5286, Université de Lyon, Université Claude Bernard Lyon1, Centre Léon Bérard, Lyon, France., Correa RJM; London Regional Cancer Program, London Health Sciences Centre Research Institute, London, Canada.; Department of Oncology, Western University, London, Canada., Shepherd TG; London Regional Cancer Program, London Health Sciences Centre Research Institute, London, Canada.; The Mary and John Knight Translational Ovarian Cancer Research Unit, London Regional Cancer Program, London, Canada.; Department of Oncology, Western University, London, Canada.; Department of Obstetrics and Gynecology, Western University, London, Canada.; Department of Anatomy and Cell Biology, Western University, London, Canada., Dick FA; London Regional Cancer Program, London Health Sciences Centre Research Institute, London, Canada.; Department of Pathology and Laboratory Medicine, University of Western Ontario, London, Canada.; Department of Oncology, Western University, London, Canada.; Children's Health Research Institute, London, Canada.

Publikováno v: ELife [Elife] 2024 Jul 18; Vol. 12. Date of Electronic Publication: 2024 Jul 18.

GO-CRISPR: A highly controlled workflow to discover gene essentiality in loss-of-function screens.

Autor: Perampalam, Pirunthan^1,2,3 (AUTHOR), McDonald, James I.^1,4 (AUTHOR), Dick, Frederick A.^1,4,5 (AUTHOR) fdick@uwo.ca

Publikováno v: PLoS ONE. 12/18/2024, Vol. 19 Issue 12, p1-16. 16p.

LKB1 and STRADα Promote Epithelial Ovarian Cancer Spheroid Cell Invasion.

Autor: Trelford, Charles B.^1,2 (AUTHOR) charles.trelford@gmail.com, Buensuceso, Adrian^1,2 (AUTHOR), Tomas, Emily^1,2 (AUTHOR), Valdes, Yudith Ramos¹ (AUTHOR), Hovey, Owen³ (AUTHOR), Li, Shawn Shun-Cheng^3,4 (AUTHOR), Shepherd, Trevor G.^1,2,5,6 (AUTHOR) tshephe6@uwo.ca

Publikováno v: Cancers. Nov2024, Vol. 16 Issue 22, p3726. 25p.

AMPK-Independent LKB1 Activity Is Required for Efficient Epithelial Ovarian Cancer Metastasis.

Autor: Buensuceso A; The Mary & John Knight Translational Ovarian Cancer Research Unit, London Regional Cancer Program, London, Ontario, Canada.; Department of Anatomy & Cell Biology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Ramos-Valdes Y; The Mary & John Knight Translational Ovarian Cancer Research Unit, London Regional Cancer Program, London, Ontario, Canada., DiMattia GE; The Mary & John Knight Translational Ovarian Cancer Research Unit, London Regional Cancer Program, London, Ontario, Canada.; Department of Biochemistry, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Department of Obstetrics & Gynaecology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Department of Oncology, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, Canada., Shepherd TG; The Mary & John Knight Translational Ovarian Cancer Research Unit, London Regional Cancer Program, London, Ontario, Canada. tshephe6@uwo.ca.; Department of Anatomy & Cell Biology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Department of Obstetrics & Gynaecology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Department of Oncology, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, Canada.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2020 Mar; Vol. 18 (3), pp. 488-500. Date of Electronic Publication: 2019 Nov 19.

In Vitro Bioassay for Damage-Associated Molecular Patterns Arising from Injured Oral Cells.

Autor: Panahipour, Layla¹ (AUTHOR) layla.panahipour@meduniwien.ac.at, Micucci, Chiara¹ (AUTHOR) chiara.micucci@studenti.unipr.it, Gelmetti, Benedetta¹ (AUTHOR) benedetta.gelmetti@studenti.unipr.it, Gruber, Reinhard^1,2,3 (AUTHOR) reinhard.gruber@meduniwien.ac.at

Publikováno v: Bioengineering (Basel). Jul2024, Vol. 11 Issue 7, p687. 12p.