Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ramona Reichenbach"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Compassionate Use (CU)/Managed Access programs provide access to locally unapproved medicines. As these programs become more global and involve a broader range of products, determining whether patients derive benefit from treatment could provide insi
Externí odkaz:
https://doaj.org/article/94f719b17d4942d182470e8cec356a19
Publikováno v:
JAMA health forum. 3(12)
This Viewpoint assesses patient access to compassionate use treatments for medical care and advocates a framework for helping to facilitate such access.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0a7d583db28d7b9136b17fde5e4123
https://pubmed.ncbi.nlm.nih.gov/36525254
https://pubmed.ncbi.nlm.nih.gov/36525254
Autor:
Paul Aliu, Séverine Sarp, Ramona Reichenbach, Sigrid Behr, Paige Fitzsimmons, Mansurahmad Shamlajee, Surya Prakash Kola, Samantha Nunes Radimerski, Emil Scosyrev
Publikováno v:
JAMA health forum. 3(4)
Compassionate use (CU) is a treatment option for patients with serious or life-threatening medical conditions that provides access to locally unlicensed medications (generally free of charge) when all available treatment options have been exhausted a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d22eb3dcb763cbd435251f7490af3e
https://pubmed.ncbi.nlm.nih.gov/36218966
https://pubmed.ncbi.nlm.nih.gov/36218966
Autor:
Barbara Barbaro, Yoshiyuki Ueno, Ramona Reichenbach, Shannon Glaser, Marco Marzioni, Domenico Alvaro, Eugenio Gaudio, Antonio Franchitto, Heather Francis, Gianfranco Alpini, Giammarco Fava, Ryun Summers, Paolo Onori, Julie Venter
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 291:G307-G317
The hepatic artery, through the peribiliary plexus, nourishes the intrahepatic biliary tree. During obstructive cholestasis, the nutritional demands of intrahepatic bile ducts are increased as a consequence of enhanced proliferation; in fact, the per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a90d9b5080a111f9bac6dadcc0e1574
https://doi.org/10.1152/ajpgi.00507.2005
https://doi.org/10.1152/ajpgi.00507.2005
Autor:
Gianfranco Alpini, Giammarco Fava, Yoshiyuki Ueno, Jo Lynne Phinizy, Ramona Reichenbach, Marco Marzioni, Domenico Alvaro, Luca Marucci, Heather Francis, Antonio Benedetti, Julie Venter, Silvia Taffetani, Shannon Glaser, Gene LeSage
Publikováno v:
Journal of Hepatology. 41:528-537
Background/Aims To evaluate if increased cholangiocyte cAMP levels alone are sufficient to enhance cholangiocyte proliferation and secretion. Methods Normal rats were treated in vivo with forskolin for two weeks. Cholangiocyte apoptosis, proliferatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed5bfac4e03e57d4817844e2f05207f
https://doi.org/10.1016/j.jhep.2004.06.009
https://doi.org/10.1016/j.jhep.2004.06.009
Autor:
J Venter, Heather Francis, Antonio Benedetti, Yoshiyuki Ueno, Ramona Reichenbach, Marco Marzioni, Giammarco Fava, Ryun Summers, Shannon Glaser, Maria Grazia Mancino, Gianfranco Alpini
Publikováno v:
The American journal of pathology. 168(2)
Chronic cholestatic liver diseases are characterized by impaired balance between proliferation and death of cholangiocytes, as well as vanishing of bile ducts and liver failure. Ursodeoxycholic acid (UDCA) is a bile acid widely used for the therapy o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e927c433ea226cc0aef06c9fdb32fd
https://pubmed.ncbi.nlm.nih.gov/16436655
https://pubmed.ncbi.nlm.nih.gov/16436655
Autor:
Yoshiyuki Ueno, Marco Marzioni, Domenico Alvaro, Luca Marucci, Heather Francis, Sharon De Morrow, Antonio Benedetti, Ramona Reichenbach, Shannon Glaser, Maria Grazia Mancino, Jo Lynne Phinizy, Giammarco Fava, Gianfranco Alpini, Ryun Summers, Julie Venter
Loss of parasympathetic innervation after vagotomy impairs cholangiocyte proliferation, which is associated with depressed cAMP levels, impaired ductal secretion, and enhanced apoptosis. Agonists that elevate cAMP levels prevent cholangiocyte apoptos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cec523e9cbe3349db2cc42502d0cb00
http://hdl.handle.net/11573/358125
http://hdl.handle.net/11573/358125
Autor:
Yoshiyuki Ueno, Ramona Reichenbach, Marco Marzioni, Domenico Alvaro, Julie Venter, Giammarco Fava, Paolo Onori, George Stoica, Shannon Glaser, Sharon De Morrow, Gianfranco Alpini, Silvia Taffetani, Cynthia J. Meininger, Heather Francis, Ryun Summers, Barbara Barbaro, Eugenio Gaudio, Antonio Franchitto
Background & Aims: Vascular endothelial growth factor (VEGF) is secreted by several epithelia and modulates cellular functions by autocrine and paracrine mechanisms. The role of VEGF in cholangiocyte pathophysiology is unknown. We evaluated the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20150ff9cffe6c5e7e30579cde45f1af
http://hdl.handle.net/11573/236151
http://hdl.handle.net/11573/236151
Autor:
Gianfranco Alpini, Giammarco Fava, Marco Marzioni, Domenico Alvaro, Heather Francis, Ramona Reichenbach, Antonio Benedetti, Cynthia J. Meininger, Silvia Taffetani, Sharon De Morrow, Ryun Summers, Julie Venter, Shannon Glaser, Luca Marucci, Tushar Patel
We studied the effect of the inhibitory neurotransmitter, γ-aminobutyric acid (GABA), in the regulation of cholangiocarcinoma growth. We determined the in vitro effect of GABA on the proliferation of the cholangiocarcinoma cell lines (Mz-ChA-1, HuH-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11628a7aac2a3a27c0074d3f39c7de0
http://hdl.handle.net/11573/114531
http://hdl.handle.net/11573/114531