Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ramona L. McCaffrey"'
Autor:
Jessica M Hameed, Ramona L McCaffrey, Andrea McCoy, Tracy Brannock, Gregory J Martin, William T Scouten, Krista Brooks, Shannon D Putnam, Mark S Riddle
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154830 (2016)
Travelers' diarrhea (TD) is the most common ailment affecting travelers, including deployed U.S. military. Continuing Promise 2011 was a 5-month humanitarian assistance/disaster response (HA/DR) military and non-governmental organization training mis
Externí odkaz:
https://doaj.org/article/34d006c66d40454d81e4877a604a1de5
Autor:
Krista M, Brooks, Reza, Zeighami, Christian J, Hansen, Ramona L, McCaffrey, Paul C F, Graf, Christopher A, Myers
Publikováno v:
MSMR. 25(8)
An estimated 179 million cases of acute gastroenteritis (AGE) occur each year in the U.S. and AGE is commonly reported within both training and deployed U.S. military populations. Beginning in 2011, the Operational Infectious Diseases laboratory at N
Publikováno v:
Journal of Innate Immunity. 8:299-313
Tularemia is a disease characterized by profound neutrophil accumulation and tissue destruction. The causative organism, Francisella tularensis, is a facultative intracellular bacterium that replicates in neutrophil cytosol, inhibits caspase activati
Autor:
Stephen R. Lindemann, Ramona L. McCaffrey, Justin T. Schwartz, Blake W. Buchan, Lee-Ann H. Allen, Bradley D. Jones, Jessica G. Moreland
Publikováno v:
Journal of Leukocyte Biology. 88:791-805
Francisella tularensis uses both pre- and post-assembly mechanisms to inhibit NADPH oxidase activity at its own phagosome and throughout infected human neutrophils. Ft is a facultative intracellular pathogen that infects many cell types, including ne
Autor:
Jerrold Weiss, William M. Nauseef, Lee-Ann H. Allen, Jason H. Barker, Nicki K. Baman, Ramona L. McCaffrey
Publikováno v:
Microbes and Infection. 11:762-769
The remarkable infectiousness of Francisella tularensis suggests that the bacterium efficiently evades innate immune responses that typically protect the host during its continuous exposure to environmental and commensal microbes. In our studies of t
Autor:
Theresa A. Storm, Anton P. McCaffrey, Thu Thao T Pham, Hiroyuki Nakai, Hui Xu, Anja Ehrhardt, Ramona L. McCaffrey, Paul Fawcett, Kusum Pandey, Sally Feuss, Mark A. Kay
Publikováno v:
Molecular Therapy. 16:931-941
Understanding host responses to viral gene therapy vectors is necessary for the development of safe and efficacious in vivo gene transfer agents. We describe the use of high-density spotted complementary DNA microarrays in monitoring the in vivo host
Publikováno v:
Journal of innate immunity. 8(3)
Tularemia is a disease characterized by profound neutrophil accumulation and tissue destruction. The causative organism, Francisella tularensis, is a facultative intracellular bacterium that replicates in neutrophil cytosol, inhibits caspase activati
Autor:
Lee-Ann H. Allen, Ramona L. McCaffrey
Publikováno v:
Journal of Leukocyte Biology. 80:1224-1230
Francisella tularensis is a Gram-negative bacterium and the causative agent of tularemia. Recent data indicate that F. tularensis replicates inside macrophages, but its fate in other cell types, including human neutrophils, is unclear. We now show th
Autor:
Edward A. Havell, Kyung Dall Lee, Mary X. D. O'Riordan, Ramona L. McCaffrey, Paul Fawcett, Patrick O. Brown, Daniel A. Portnoy
Publikováno v:
Proceedings of the National Academy of Sciences. 101:11386-11391
Innate and adaptive immunity depends critically on host recognition of pathogen-associated molecules. Toll-like receptors (TLRs) are key mediators of pathogen surveillance at the cell or phagocytic vacuole surface. However, mechanisms underlying reco
Autor:
Bradley D. Jones, Lee-Ann H. Allen, Blake W. Buchan, Stephen R. Lindemann, Ramona L. McCaffrey
Publikováno v:
Infection and immunity. 77(6)
Francisella tularensis, the etiological agent of tularemia, is capable of infecting a wide range of animals and causes a severe, lethal disease in humans. The pathogen evades killing by cells of the innate immune system utilizing genes encoding a pat