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pro vyhledávání: '"Ramona F. Sowade"'
Autor:
Ramona F. Sowade, Thomas R. Jahn
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Seeding of amyloid beta from one brain region to another is thought to contribute to the progression of Alzheimer’s disease, although to date most studies have depended on inoculation of animals with exogenous amyloid. Here the authors describe a g
Externí odkaz:
https://doaj.org/article/5ea36811b67d402494721fe6e7ac972b
Autor:
Ramona F. Sowade, Susanne Schoch, Anne Woitecki, Albert J. Becker, Johannes Alexander Müller, Karen M.J. van Loo
Publikováno v:
The Journal of Neuroscience. 36:2561-2570
Neuronal degeneration represents a pathogenetic hallmark after different brain insults, such as ischemia and status epilepticus (SE). Excessive release of glutamate triggered by pathophysiologic synaptic activity has been put forward as key mechanism