Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ramona Ettig"'
Autor:
Christine Vogler, Claudia Huber, Tanja Waldmann, Ramona Ettig, Lora Braun, Annalisa Izzo, Sylvain Daujat, Isabelle Chassignet, Andres Joaquin Lopez-Contreras, Oscar Fernandez-Capetillo, Miroslav Dundr, Karsten Rippe, Gernot Längst, Robert Schneider
Publikováno v:
PLoS Genetics, Vol 6, Iss 12, p e1001234 (2010)
The tails of histone proteins are central players for all chromatin-mediated processes. Whereas the N-terminal histone tails have been studied extensively, little is known about the function of the H2A C-terminus. Here, we show that the H2A C-termina
Externí odkaz:
https://doaj.org/article/e4101e6be0b148c297127a37c5d29009
Publikováno v:
Biopolymers. 95:435-447
The folding of the nucleosome chain into a chromatin fiber is a central factor for controlling the DNA access of protein factors involved in transcription, DNA replication and repair. Force spectroscopy experiments with chromatin fibers are ideally s
Publikováno v:
Biophysical Journal. 98(6):1028-1037
The three-dimensional structure of chromatin affects DNA accessibility and is therefore a key regulator of gene expression. However, the path of the DNA between consecutive nucleosomes, and the resulting chromatin fiber organization remain controvers
Publikováno v:
Biophysical journal. 107(9)
Chromatin conformation is dynamic and heterogeneous with respect to nucleosome positions, which can be changed by chromatin remodeling complexes in the cell. These molecular machines hydrolyze ATP to translocate or evict nucleosomes, and establish lo
Publikováno v:
Biophysical journal. 101(8)
The nucleosome complex of DNA wrapped around a histone protein octamer organizes the genome of eukaryotes and regulates the access of protein factors to the DNA. We performed molecular dynamics simulations of the nucleosome in explicit water to study
Autor:
Nick, Kepper, Ramona, Ettig, Frank, Dickmann, Rene, Stehr, Frank G, Grosveld, Gero, Wedemann, Tobias A, Knoch
Publikováno v:
Studies in health technology and informatics. 159
Especially in the life-science and the health-care sectors the huge IT requirements are imminent due to the large and complex systems to be analysed and simulated. Grid infrastructures play here a rapidly increasing role for research, diagnostics, an
Publikováno v:
Biophysical Journal. 102:482a
The three-dimensional structure of chromatin is a key factor for controlling DNA accessibility, replication and repair. Despite numerous experimental efforts many details of the spatial organization and structural regulation mechanisms of chromatin r
Publikováno v:
Biophysical Journal. (8):2597-2607
Nucleosomes, the basic repeating unit of chromatin, consist of 147 basepairs of DNA that are wrapped in almost two turns around a histone protein octamer core. Because ∼3/4 of the human genomic DNA is found within nucleosomes, their position and DN
Publikováno v:
Biophysical Journal. (3):55a
In the nucleus of higher organisms the DNA is organized by histone proteins into a nucleoprotein complex termed chromatin. This packing controls DNA accessibility and is therefore an important factor for the control of gene expression.We developed a