Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ramona Crescenzo"'
Autor:
Balpreet Bhogal, Barbara A. Weir, Ramona Crescenzo, Ann Marien, Min Chul Kwon, Ulrike Philippar, Glenn S. Cowley
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
The methyltransferase domain of DNA methyltransferase protein 1 is an essential functional domain in acute myeloid leukemia, which is independent of DNMT3A mutation.
Externí odkaz:
https://doaj.org/article/4cb0bcf1331e411599809aa13de6b330
Autor:
Florencia Cayrol, Pannee Praditsuktavorn, Tharu M. Fernando, Nicholas Kwiatkowski, Rosella Marullo, M. Nieves Calvo-Vidal, Jude Phillip, Benet Pera, Shao Ning Yang, Kaipol Takpradit, Lidia Roman, Marcello Gaudiano, Ramona Crescenzo, Jia Ruan, Giorgio Inghirami, Tinghu Zhang, Graciela Cremaschi, Nathanael S. Gray, Leandro Cerchietti
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
T-cell lymphomas are aggressive diseases associated with poor outcome. Here, the authors show that the THZ1, a CDK7 inhibitor, suppresses STAT transcriptional activity leading to apoptosis and sensitization to BCL2 inhibitors in T-cell lymphomas.
Externí odkaz:
https://doaj.org/article/d9b0eca4497a40c1b2e964a28298864d
Autor:
Balpreet Bhogal, Barbara A. Weir, Ramona Crescenzo, Ann Marien, Min Chul Kwon, Ulrike Philippar, Glenn S. Cowley
Publikováno v:
Communications biology. 5(1)
Aberrant DNA methylation patterns are a prominent feature of cancer. Methylation of DNA is mediated by the DNA methyltransferase (DNMT) protein family, which regulates de novo (DNMT3A and DNMT3B) and maintenance (DNMT1) methylation. Mutations in DNMT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75688cd0955d1f690bbb87f7d68fdebc
https://pubmed.ncbi.nlm.nih.gov/36329185
https://pubmed.ncbi.nlm.nih.gov/36329185
Autor:
Florencia Cayrol, Pannee Praditsuktavorn, Tharu M. Fernando, Nicholas Kwiatkowski, Rossella Marullo, M. Nieves Calvo-Vidal, Jude Phillip, Benet Pera, Shao Ning Yang, Kaipol Takpradit, Lidia Roman, Marcello Gaudiano, Ramona Crescenzo, Jia Ruan, Giorgio Inghirami, Tinghu Zhang, Graciela Cremaschi, Nathanael S Gray, Leandro Cerchietti
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 8: Article number: 14290 (2017); Published: 30 January 2017; Updated: 20 February 2017 The original version of this Article contained an error in the spelling of the author Rossella Marullo, which was incorrectly given as Rosell
Externí odkaz:
https://doaj.org/article/4f6d287b1b314c20bd2687a9811a5e95
Autor:
Maria E. Riveiro, Heng Pan, Leandro Cerchietti, Ramona Crescenzo, Valentina Vurchio, Giorgio Inghirami, Francesco Bertoni, Mangeng Cheng, Olivier Elemento, Maria Todaro, Andrea Rinaldi, Ivo Kwee, Michela Boi, Shao Ning Yang, John Moon, Esteban Cvitkovic
Publikováno v:
Oncotarget
// Michela Boi 1, 2, * , Maria Todaro 1, 2, * , Valentina Vurchio 1 , Shao Ning Yang 3 , John Moon 3 , Ivo Kwee 4, 5, 6 , Andrea Rinaldi 4 , Heng Pan 7, 8 , Ramona Crescenzo 1, 2 , Mangeng Cheng 9 , Leandro Cerchietti 3 , Olivier Elemento 7, 8 , Mari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7911b4c2e9a1e2f01a62ddbb11a502c4
https://doi.org/10.18632/oncotarget.12876
https://doi.org/10.18632/oncotarget.12876
Autor:
Min Chul Kwon, Glenn S. Cowley, Ramona Crescenzo, Ricardo Attar, Balpreet Bhogal, Barbara A. Weir, David Pocalyko, Ulrike Philippar
Publikováno v:
Cancer Research. 78:1383-1383
DNA methylation is an epigenetic mechanism that regulates gene expression during many stages of development, including genomic imprinting, stem cell regulation, and X-chromosome inactivation. Moreover, aberrant DNA methylation patterns, characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14d1a961844cc529ec9c9a32e937e7cf
https://doi.org/10.1158/1538-7445.am2018-1383
https://doi.org/10.1158/1538-7445.am2018-1383
Autor:
Leandro Cerchietti, Florencia Cayrol, Kaipol Takpradit, Tinghu Zhang, Pannee Praditsuktavorn, Graciela Cremaschi, Rossella Marullo, Tharu M. Fernando, Marcello Gaudiano, Nicholas Kwiatkowski, Nathanael S. Gray, Jude M. Phillip, Giorgio Inghirami, M. Nieves Calvo-Vidal, Lidia Roman, Benet Pera, Jia Ruan, Shao Ning Yang, Ramona Crescenzo
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 8: Article number: 14290 (2017); Published: 30 January 2017; Updated: 20 February 2017 The original version of this Article contained an error in the spelling of the author Rossella Marullo, which was incorrectly given as Rosell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09a55bb4aba47dc45d5be1a4eb128cb
https://doi.org/10.1038/ncomms14747
https://doi.org/10.1038/ncomms14747
Autor:
Pannee Praditsuktavorn, Leandro Cerchietti, Tinghu Zhang, Ramona Crescenzo, Rossella Marullo, Nicholas Kwiatkowski, Tharu M. Fernando, Kaipol Takpradit, Nathanael S. Gray, Giorgio Inghirami, Benet Pera, Marcello Gaudiano, Shao Ning Yang, Florencia Cayrol, Jia Ruan, M. Nieves Calvo-Vidal, Graciela Cremaschi, Lidia Roman, Jude M. Phillip
Publikováno v:
Nature Communications
Nature Communications. 2017;8:14290
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications. 2017;8:14290
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Peripheral T-cell lymphomas (PTCL) are aggressive diseases with poor response to chemotherapy and dismal survival. Identification of effective strategies to target PTCL biology represents an urgent need. Here we report that PTCL are sensitive to tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8163cfcb4091b44cbed66dfff4fe549d
http://europepmc.org/articles/PMC5290269
http://europepmc.org/articles/PMC5290269
Autor:
Lorenzo Cerroni, Laurence Mevellec, Andreas Rosenwald, Giorgio Inghirami, Luigi Barbarossa, Elena Lasorsa, Enrico Tiacci, Miguel A. Piris, Francesco Bertoni, Davide Rossi, Elisabetta Ercole, Nicoletta Chiesa, Filomena Di Giacomo, Domenico Novero, Maria Todaro, Alberto Zamò, Jorge Vialard, Ramona Crescenzo, Alexander Tzankov, Andrea Rinaldi, Lukas Kenner, Leonard D. Shultz, Francesco Abate, Thomas Tousseyn, Raul Rabadan, Javeed Iqbal, Dennis D. Weisenburger, Brunangelo Falini, Carmela Ciardullo, Elisa Ficarra, Wing C. Chan, Gianluca Gaidano, Elisa Spaccarotella, Andrea Acquaviva, Roberto Piva, Stefano Pileri, Fabrizio Tabbò, Marcello Gaudiano, Michela Boi, Marco Paulli, Maurilio Ponzoni
JAK/STAT3 signaling pathway is often deregulated in hematopoietic disorders including peripheral T-cell lymphoma. We describe two novel mechanisms leading to the constitutive activation of STAT3 in ALK- ALCL. Oncogenic JAK1 or STAT3 mutations are ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a9d987f67c88511b8a93dfda4325af
http://hdl.handle.net/11583/2598380
http://hdl.handle.net/11583/2598380
Autor:
Ramona Crescenzo, Giorgio Inghirami
Publikováno v:
Current opinion in pharmacology. 23
The anaplastic lymphoma kinase (ALK) gene is a member of the insulin receptor superfamily and it has been associated with more than twenty distinct chimera, including established drivers of several human cancers. Multiple clinical trials have proven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6597bc865c4197a3516cd844231d84
https://pubmed.ncbi.nlm.nih.gov/26051994
https://pubmed.ncbi.nlm.nih.gov/26051994