Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ramona, Bella"'
Autor:
Prasanta K. Dash, Rafal Kaminski, Ramona Bella, Hang Su, Saumi Mathews, Taha M. Ahooyi, Chen Chen, Pietro Mancuso, Rahsan Sariyer, Pasquale Ferrante, Martina Donadoni, Jake A. Robinson, Brady Sillman, Zhiyi Lin, James R. Hilaire, Mary Banoub, Monalisha Elango, Nagsen Gautam, R. Lee Mosley, Larisa Y. Poluektova, JoEllyn McMillan, Aditya N. Bade, Santhi Gorantla, Ilker K. Sariyer, Tricia H. Burdo, Won-Bin Young, Shohreh Amini, Jennifer Gordon, Jeffrey M. Jacobson, Benson Edagwa, Kamel Khalili, Howard E. Gendelman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-20 (2019)
Here, the authors show that sequential treatment with long-acting slow-effective release ART and AAV9- based delivery of CRISPR-Cas9 results in undetectable levels of virus and integrated DNA in a subset of humanized HIV-1 infected mice. This proof-o
Externí odkaz:
https://doaj.org/article/ad4b010214414d8c84777d8ae90f684b
Autor:
Ramona Bella, Rafal Kaminski, Pietro Mancuso, Won-Bin Young, Chen Chen, Rahsan Sariyer, Tracy Fischer, Shohreh Amini, Pasquale Ferrante, Jeffrey M. Jacobson, Fatah Kashanchi, Kamel Khalili
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 12, Iss , Pp 275-282 (2018)
We used NOD/SCID mice, also known as NRG, to assess the ability of lentivirus-mediated intravenous delivery of CRISPR in editing the HIV-1 genome from the circulating PBMC engrafts, some of which homed within several animal solid tissues. Lentivirus-
Externí odkaz:
https://doaj.org/article/c3b71237f904449d850998e4e755e66e
Autor:
Santhi Gorantla, James R. Hilaire, Won Bin Young, Shohreh Amini, JoEllyn M McMillan, Brady Sillman, Chen Chen, Hang Su, Mary G. Banoub, Kamel Khalili, Howard E. Gendelman, Prasanta K. Dash, Jennifer Gordon, Larisa Y. Poluektova, Nagsen Gautam, Martina Donadoni, Rahsan Sariyer, Pietro Mancuso, Saumi Mathews, Rafal Kaminski, Monalisha Elango, R. Lee Mosley, Tricia H. Burdo, Jeffrey M. Jacobson, Benson J Edagwa, Taha Mohseni Ahooyi, Pasquale Ferrante, Jake A. Robinson, Zhiyi Lin, Ramona Bella, Ilker Kudret Sariyer, Aditya N. Bade
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-20 (2019)
Nature Communications
Nature Communications
Elimination of HIV-1 requires clearance and removal of integrated proviral DNA from infected cells and tissues. Here, sequential long-acting slow-effective release antiviral therapy (LASER ART) and CRISPR-Cas9 demonstrate viral clearance in latent in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b27b73c3e4c0b82ed8decf5430a2d869
https://doaj.org/article/ad4b010214414d8c84777d8ae90f684b
https://doaj.org/article/ad4b010214414d8c84777d8ae90f684b
Autor:
Fatah Kashanchi, Tracy Fischer, Pasquale Ferrante, Jeffrey M. Jacobson, Rahsan Sariyer, Shohreh Amini, Chen Chen, Won-Bin Young, Rafal Kaminski, Kamel Khalili, Pietro Mancuso, Ramona Bella
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 275-282 (2018)
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 275-282 (2018)
We used NOD/SCID mice, also known as NRG, to assess the ability of lentivirus-mediated intravenous delivery of CRISPR in editing the HIV-1 genome from the circulating PBMC engrafts, some of which homed within several animal solid tissues. Lentivirus-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef016592c4a0cc81e6e09e3a084c9034
http://europepmc.org/articles/PMC6011019
http://europepmc.org/articles/PMC6011019
Autor:
Ramona Bella, Luc Bertrand, Andrea J. Yool, Alessandra Ghigo, Lauriane Y. M. Michel, Christophe Beauloye, Simonetta Geninatti-Crich, Virginie Montiel, Patrick Gilon, Dimitri Gilis, Pak Hin Chow, Malte Tiburcy, Charlotte Farah, Sandrine Horman, Olivier Devuyst, Hrag Esfahani, Huguette Debaix, Caroline Bouzin, Wolfram H. Zimmermann, Thomas Michel, Flavia Dei Zotti, Marianne Rooman, Jean-Louis Vanoverschelde, H. Llewelyn Roderick, Davide Brusa, Olaf Bergmann, Jean-Philippe Deglasse, Emma L. Robinson, Jean-Luc Balligand, Delphine De Mulder, Benjamin Steinhorn, Jean-Christophe Jonas
Publikováno v:
Science translational medicine, Vol. 12, no. 564, p. eaay2176 [1-16] (2020)
Science Translational Medicine, 12 (564
Science Translational Medicine, 12 (564
Pathological remodeling of the myocardium has long been known to involve oxidant signaling, but strategies using systemic antioxidants have generally failed to prevent it. We sought to identify key regulators of oxidant-mediated cardiac hypertrophy a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7058dd2d19557399679fc1154476cfe
https://hdl.handle.net/2078.1/236233
https://hdl.handle.net/2078.1/236233
Autor:
Rafal Kaminski, Yilan Chen, Julian Salkind, Ramona Bella, Won-bin Young, Pasquale Ferrante, Jonathan Karn, Thomas Malcolm, Wenhui Hu, Kamel Khalili
Publikováno v:
Scientific Reports
The CRISPR/Cas9 gene editing method is comprised of the guide RNA (gRNA) to target a specific DNA sequence for cleavage and the Cas9 endonuclease for introducing breaks in the double-stranded DNA identified by the gRNA. Co-expression of both a multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bab5f69857c99b3181d56b53b85654a
http://europepmc.org/articles/PMC4985742
http://europepmc.org/articles/PMC4985742
Autor:
Lucia, Signorini, Mattia, Croci, Renzo, Boldorini, Rafael Brandao, Varella, Francesca, Elia, Silvia, Carluccio, Sonia, Villani, Ramona, Bella, Pasquale, Ferrante, Serena, Delbue
BK polyomavirus (BKV) has a worldwide seroprevalence of approximately 90%. After primary infection, BKV establishes a life-long latency within the urogenital tract. The severe immunological impairment occurring in renal transplant recipients leads to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0a51c8685e2a681c2095c2b801670019
http://hdl.handle.net/10281/154975
http://hdl.handle.net/10281/154975