Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ramon Portillo"'
Autor:
Rona Karahoda, Veronika Vachalova, Ramon Portillo, Filip Mahrla, Mireia Viñas-Noguera, Cilia Abad, Frantisek Staud
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Catecholamines norepinephrine and dopamine have been implicated in numerous physiological processes within the central nervous system. Emerging evidence has highlighted the importance of tightly regulated monoamine levels for placental funct
Externí odkaz:
https://doaj.org/article/3c1b805814194126a5b7b073f122f215
Autor:
Abraham Marquez Alcaide, Hao Yan, Xuchen Wang, Jose I. Leon, Ramon Portillo, Giampaolo Buticchi, Sergio Vazquez, Vito Giuseppe Monopoli, Marco Liserre, Leopoldo G. Franquelo
Publikováno v:
IEEE Access, Vol 9, Pp 56115-56126 (2021)
Common-mode voltage (CMV) in electric drives causes leakage current causing consequently EMI problems, loss and reduction of their components’ lifetime. Several solutions have been proposed which usually lead to higher cost because additional compo
Externí odkaz:
https://doaj.org/article/7faf4c8730a04be28d30bf19b396d22e
Autor:
Abraham Marquez Alcaide, Jose I. Leon, Marta Laguna, Francisco Gonzalez-Rodriguez, Ramon Portillo, Eduardo Zafra-Ratia, Sergio Vazquez, Leopoldo G. Franquelo, Sertac Bayhan, Haitham Abu-Rub
Publikováno v:
Energies, Vol 13, Iss 7, p 1659 (2020)
Hand-in-hand with the smart-grid paradigm development, power converters used in high-power applications are facing important challenges related to efficiency and power quality. To overcome these issues, the pre-programmed Pulse-Width Modulation (PWM)
Externí odkaz:
https://doaj.org/article/2d34631c5c294902bf155e682362fa29
Autor:
Anselm Morell, Youssif Budagaga, Dimitrios Vagiannis, Yu Zhang, Lenka Laštovičková, Eva Novotná, Andrew Haddad, Melodie Haddad, Ramon Portillo, Jakub Hofman, Vladimír Wsól
Publikováno v:
SSRN Electronic Journal.
Targeting mutations that trigger acute myeloid leukaemia (AML) has emerged as a refined therapeutic approach in recent years. Enasidenib (Idhifa) is the first selective inhibitor of mutated forms of isocitrate dehydrogenase 2 (IDH2) approved against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ffe4d9fda321d86ee2ad9aef7349d38
https://doi.org/10.2139/ssrn.4050268
https://doi.org/10.2139/ssrn.4050268
Autor:
Wsól, Anselm Morell, Lucie Čermáková, Eva Novotná, Lenka Laštovičková, Melodie Haddad, Andrew Haddad, Ramon Portillo, Vladimír
Publikováno v:
Cancers; Volume 12; Issue 12; Pages: 3731
Over the last few years, aldo-keto reductase family 1 member C3 (AKR1C3) has been associated with the emergence of multidrug resistance (MDR), thereby hindering chemotherapy against cancer. In particular, impaired efficacy of the gold standards of in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::1fc94d63382b394b67bd973d5f101169
Autor:
Anselm Morell, Lucie Čermáková, Eva Novotná, Lenka Laštovičková, Melodie Haddad, Andrew Haddad, Ramon Portillo, Vladimír Wsól
Publikováno v:
Cancers
Cancers, Vol 12, Iss 3731, p 3731 (2020)
Cancers, Vol 12, Iss 3731, p 3731 (2020)
Simple Summary The enzyme aldo-keto reductase 1C3 (AKR1C3) is present in several cancers, in which it is capable of actively metabolising different chemotherapy drugs and decreasing their cytotoxic effects. Therefore, the combination with specific in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::85edee2de57732e7efb84240b6effd22
http://europepmc.org/articles/PMC7764606
http://europepmc.org/articles/PMC7764606
Autor:
Cilia Abad, Rona Karahoda, Petr Kastner, Ramon Portillo, Hana Horackova, Radim Kucera, Petr Nachtigal, Frantisek Staud
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7578, p 7578 (2020)
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7578, p 7578 (2020)
Placental homeostasis of tryptophan is essential for fetal development and programming. The two main metabolic pathways (serotonin and kynurenine) produce bioactive metabolites with immunosuppressive, neurotoxic, or neuroprotective properties and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8235e320634deea9d1d5b7b5e9111f6f
Autor:
Nieves Atienza, Natalia de Castro, Carmen Cortés, M. Ángeles Garrido, Clara I. Grima, Gregorio Hernández, Alberto Márquez, Auxiliadora Moreno-González, Martin Nöllenburg, José Ramon Portillo, Pedro Reyes, Jesús Valenzuela, Maria Trinidad Villar, Alexander Wolff
Publikováno v:
Journal of Computational Geometry, Vol 3, Iss 1 (2012)
We study problems that arise in the context of covering certain geometric objects called seeds (e.g., points or disks) by a set of other geometric objects called cover (e.g., a set of disks or homothetic triangles). We insist that the interiors of th
Externí odkaz:
https://doaj.org/article/cb7a8158ae1d47b0a1d5fdac35fad3c1
Autor:
Petr Solich, Anselm Morell, Neslihan Büküm, Eva Novotná, Ramon Portillo, Vladimír Wsól, Lucie Čermáková, Jana Želazková, Lenka Laštovičková
Publikováno v:
Biochemical Pharmacology. 192:114710
Bcr-Abl tyrosine kinase inhibitors significantly improved Philadelphia chromosome-positive leukaemia therapy. Apart from Bcr-Abl kinase, imatinib, dasatinib, nilotinib, bosutinib and ponatinib are known to have additional off-target effects that migh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74366657cd0eab8e29f92e1700e05cef
https://doi.org/10.1016/j.bcp.2021.114710
https://doi.org/10.1016/j.bcp.2021.114710
Publikováno v:
Experimental Parasitology. 125:100-105
The role of calcium and its relevance have been deeply revised with respect to trypanosomatids, as the mechanism by which calcium enters trypanosomes was, until now, not well understood. There is evidence supporting the presence of a nAChR in another
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ea2ddf1053dbea6238ec5872daf7fc
https://doi.org/10.1016/j.exppara.2010.01.006
https://doi.org/10.1016/j.exppara.2010.01.006