Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Ramon O. Vidal"'
Autor:
Eugenio F. Fornasiero, Sunit Mandad, Hanna Wildhagen, Mihai Alevra, Burkhard Rammner, Sarva Keihani, Felipe Opazo, Inga Urban, Till Ischebeck, M. Sadman Sakib, Maryam K. Fard, Koray Kirli, Tonatiuh Pena Centeno, Ramon O. Vidal, Raza-Ur Rahman, Eva Benito, André Fischer, Sven Dennerlein, Peter Rehling, Ivo Feussner, Stefan Bonn, Mikael Simons, Henning Urlaub, Silvio O. Rizzoli
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Measuring precise protein turnover rates in animals is technically challenging at the proteomic level. Here, Fornasiero and colleagues use isotopic labeling with mass spectrometry and mathematical modeling to accurately determine protein lifetimes in
Externí odkaz:
https://doaj.org/article/37f09442e22e41daa48bdc27c646c649
Autor:
Ahmed A.H. Ali, Fatma Abdallah, Ramon O. Vidal, Robert Geffers, Mohamed Samir, Stefan Bonn, Vincenzo Capece, Ashraf Hussein, Frank Pessler, Frauke Seehusen
Publikováno v:
RNA biology 17(1), 112-124 (2019). doi:10.1080/15476286.2019.1669879
RNA Biol
RNA Biol
The duck represents an important reservoir of influenza viruses for transmission to other avian and mammalian hosts, including humans. The increased pathogenicity of the recently emerging clades of highly pathogenic avian influenza (HPAI) viruses of
Autor:
Jean-Marc Lacape, Michel Claverie, Ramon O Vidal, Marcelo F Carazzolle, Gonçalo A Guimarães Pereira, Manuel Ruiz, Martial Pré, Danny Llewellyn, Yves Al-Ghazi, John Jacobs, Alexis Dereeper, Stéphanie Huguet, Marc Giband, Claire Lanaud
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48855 (2012)
Cotton (Gossypium) fiber is the most prevalent natural product used in the textile industry. The two major cultivated species, G. hirsutum (Gh) and G. barbadense (Gb), are allotetraploids with contrasting fiber quality properties. To better understan
Externí odkaz:
https://doaj.org/article/915bb0fb377f481bbe4170cfdaafbe81
Autor:
Alison Simmons, Christine Harnack, Michael Sigal, Hilmar Berger, Sascha Sauer, Agne Antanaviciute, Thomas F. Meyer, Ramon O. Vidal
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications
The colonic epithelial turnover is driven by crypt-base stem cells that express the R-spondin receptor Lgr5. Signals that regulate epithelial regeneration upon stem cell injury are largely unknown. Here, we explore the dynamics of Wnt signaling in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c5ee3b06e6523dfe756d650f125ba6
http://edoc.mdc-berlin.de/18455/7/18455suppl.zip
http://edoc.mdc-berlin.de/18455/7/18455suppl.zip
Autor:
Frederike Weber, Stefan Bonn, Karl Toischer, Katrin Streckfuss-Bömeke, Sara Khadjeh, Setare Torkieh, Belal A. Mohamed, Ramon O. Vidal, Lukas Cyganek, Malte Tiburcy, Dawid Lbik, Vanessa Hindmarsh, Gerd Hasenfuss
Publikováno v:
Basic Research in Cardiology
Basic research in cardiology 115(3), 27 (2020). doi:10.1007/s00395-020-0784-4
Basic research in cardiology 115(3), 27 (2020). doi:10.1007/s00395-020-0784-4
Heart failure is a major health problem worldwide with a significant morbidity and mortality rate. Although studied extensively in animal models, data from patients at the compensated disease stage are lacking. We sampled myocardium biopsies from aor
Autor:
Tonatiuh Pena Centeno, Koray Kirli, Sunit Mandad, Inga Urban, Hanna Wildhagen, Ramon O. Vidal, Eva Benito, Burkhard Rammner, Eugenio F. Fornasiero, Andre Fischer, Peter Rehling, Ivo Feussner, Sven Dennerlein, Roya Yousefi, Till Ischebeck, Stefan Bonn, Sarva Keihani, Raza-Ur Rahman, Felipe Opazo, Henning Urlaub, Silvio O. Rizzoli
Publikováno v:
Scientific reports 8(1), 16913 (2018). doi:10.1038/s41598-018-35277-8
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-19 (2018)
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-19 (2018)
The homeostasis of the proteome depends on the tight regulation of the mRNA and protein abundances, of the translation rates, and of the protein lifetimes. Results from several studies on prokaryotes or eukaryotic cell cultures have suggested that pr
Autor:
Eckhard Wolf, Ramon O. Vidal, Anna Matynia, Frauke Neff, Birgit Rathkolb, Valerie Gailus-Durner, Anna-Lena Schütz, Helmut Fuchs, Gerhard Ehninger, Dan Ehninger, Devon Ryan, Dirk H. Busch, Jan Rozman, Cornelia Prehn, Martin Hrabě de Angelis, Stefan Bonn, Melvin Schleif, Isabelle Lehmann, Walker S. Jackson, Michel E. Mickael, Jerzy Adamski, Magali Hennion, Thure Adler, Kristin S. Henzel, Brandon L. Pearson, Susanne Schröder, Kan Xie, Marco Weiergräber
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America 115(10), E2348-E2357 (2018). doi:10.1073/pnas.1707337115
Proc. Natl. Acad. Sci. U.S.A. 115, E2348-E2357 (2018)
Proceedings of the National Academy of Sciences of the United States of America 115(10), E2348-E2357 (2018). doi:10.1073/pnas.1707337115
Proc. Natl. Acad. Sci. U.S.A. 115, E2348-E2357 (2018)
Significance Aging-associated diseases are increasingly common in an aging global population. However, the contributors and origins of differential risk for unhealthy aging remain poorly understood. Using a mouse model, we found that offspring of age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbd4bb7ab35140f3d778069ba8158ae
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-192395
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-192395
Autor:
Silvio O. Rizzoli, Ramon O. Vidal, Sven Dennerlein, Eugenio F. Fornasiero, Till Ischebeck, M. Sadman Sakib, Andre Fischer, Peter Rehling, Ivo Feussner, Mikael Simons, Maryam K. Fard, Burkhard Rammner, Sarva Keihani, Stefan Bonn, Raza-Ur Rahman, Henning Urlaub, Tonatiuh Pena Centeno, Felipe Opazo, Inga Urban, Mihai Alevra, Koray Kirli, Eva Benito, Sunit Mandad, Hanna Wildhagen
Publikováno v:
Nature Communications 9(1), 4230 (2018). doi:10.1038/s41467-018-06519-0
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
The turnover of brain proteins is critical for organism survival, and its perturbations are linked to pathology. Nevertheless, protein lifetimes have been difficult to obtain in vivo. They are readily measured in vitro by feeding cells with isotopica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d18c06f4a83bed8d688f03832f3121c6
Autor:
Klas Hatje, Ashish Rajput, Raza-Ur Rahman, Björn Hammesfahr, Dominic Simm, Vikas Bansal, Ramon O. Vidal, Martin Kollmar, Michel E. Mickael, Ting Sun, Stefan Bonn
Publikováno v:
Molecular Systems Biology
Molecular systems biology 13(12), 959 (2017). doi:10.15252/msb.20177728
Molecular systems biology 13(12), 959 (2017). doi:10.15252/msb.20177728
Mutually exclusive splicing of exons is a mechanism of functional gene and protein diversification with pivotal roles in organismal development and diseases such as Timothy syndrome, cardiomyopathy and cancer in humans. In order to obtain a first gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5da64baeddf4ca1a4f6b1cc15794252
https://hdl.handle.net/11858/00-001M-0000-002E-8F7C-011858/00-001M-0000-002E-8F82-F11858/00-001M-0000-002E-8F83-D11858/00-001M-0000-002E-8F84-B11858/00-001M-0000-002E-8F86-711858/00-001M-0000-002E-8F87-511858/00-001M-0000-002E-8F88-311858/00-001M-0000-002E-8F89-111858/00-001M-0000-002E-8F85-911858/00-001M-0000-002E-8F80-411858/00-001M-0000-002E-8F81-211858/00-001M-0000-002E-8F7E-C11858/00-001M-0000-002E-8F7F-A
https://hdl.handle.net/11858/00-001M-0000-002E-8F7C-011858/00-001M-0000-002E-8F82-F11858/00-001M-0000-002E-8F83-D11858/00-001M-0000-002E-8F84-B11858/00-001M-0000-002E-8F86-711858/00-001M-0000-002E-8F87-511858/00-001M-0000-002E-8F88-311858/00-001M-0000-002E-8F89-111858/00-001M-0000-002E-8F85-911858/00-001M-0000-002E-8F80-411858/00-001M-0000-002E-8F81-211858/00-001M-0000-002E-8F7E-C11858/00-001M-0000-002E-8F7F-A
Autor:
Andreas Perrot, Sara Khadjeh, Jan Haas, Cemil Özcelik, Malte Tiburcy, Samuel Sossalla, Kaomei Guan, Wolfram-Hubertus Zimmermann, Sabine Rebs, Wener Li, Claudia Fischer, Xiaojing Luo, Benjamin Meder, Ramon O. Vidal, Wolfgang A. Linke, Stefan Bonn, Gerd Hasenfuss, Andrey Fomin, Katrin Streckfuss-Bömeke
Publikováno v:
Journal of molecular and cellular cardiology 113, 9-21 (2017). doi:10.1016/j.yjmcc.2017.09.008
The ability to generate patient-specific induced pluripotent stem cells (iPSCs) provides a unique opportunity for modeling heart disease in vitro. In this study, we generated iPSCs from a patient with dilated cardiomyopathy (DCM) caused by a missense